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The map label for this gene is yrhP [H]

Identifier: 13476348

GI number: 13476348

Start: 6328085

End: 6328711

Strand: Reverse

Name: yrhP [H]

Synonym: mll7642

Alternate gene names: 13476348

Gene position: 6328711-6328085 (Counterclockwise)

Preceding gene: 13476349

Following gene: 13476347

Centisome position: 89.95

GC content: 60.77

Gene sequence:

>627_bases
ATGATCGATTTGTCGACATCGATCGCCTATACCGCCGTCGTGCTCGGCTTTGTCTTTATTCCAGGTCCGGCCACGCTGCT
GACGATCGCTCGGGCAACGAGTTCGGGAACGAAGGTCGGGATCGCGACCGGCGCCGGGATCGCGGCCGGCGACATTTTTC
ACACTGTCATGGCGATACTCGGCATCTCGGCGATCATCGCCACCTCGGCGACGCTGTTCAGCATCGTAAAATATATCGGT
GCGGCCTACCTCGTTTACCTCGGCATTCGCGCCATCATCGAGAAAACGCCGGCCGATCCCTCTGCCGGCGCGCTTGCGAT
CTCCGCCGGCAAGGCGTTTCGGCAGGCCGTCCTGACCGAAGTGCTCAACCCCAAGACCGCACTGTTTTTCCTAGCATTCC
TGCCTCAGTTCGTACGGCCCGAAAACGGAACGGTGATGCTTCAATTGGCCGTGCTGGGAATTGTCTTCGTCGTGCTCGGC
CTTTTCAGCACGGTCGTCTTTGCCGTGAGCGCCGGTCGCCTCGGCTCTTTCCTGCGCCGAAATCCGACCGTGCTGAAATG
GCAGGGCAAGGTTGTCGGCGGCATCTACTGTGCCTTGGGCGTGCGCCTGGCCTTGCAGCAACGCTGA

Upstream 100 bases:

>100_bases
GGGCCTCCGGCCGGTTTTCAAGGCTGGAGGAGATCGCCTATACCTATTCCTTCGCGCTGAAGGTTACAGGCAAGGCGCAG
CTTATCGAGGAGACCCTCCG

Downstream 100 bases:

>100_bases
GGCTCCGGACAGCACGTTCACTTTTGGGTTCAGCGATCATGACTTTTTGAATTCCGCATTGCTTATTTCCCCTCGCAATT
GCGATGGTCGCGCGTTACCC

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MIDLSTSIAYTAVVLGFVFIPGPATLLTIARATSSGTKVGIATGAGIAAGDIFHTVMAILGISAIIATSATLFSIVKYIG
AAYLVYLGIRAIIEKTPADPSAGALAISAGKAFRQAVLTEVLNPKTALFFLAFLPQFVRPENGTVMLQLAVLGIVFVVLG
LFSTVVFAVSAGRLGSFLRRNPTVLKWQGKVVGGIYCALGVRLALQQR

Sequences:

>Translated_208_residues
MIDLSTSIAYTAVVLGFVFIPGPATLLTIARATSSGTKVGIATGAGIAAGDIFHTVMAILGISAIIATSATLFSIVKYIG
AAYLVYLGIRAIIEKTPADPSAGALAISAGKAFRQAVLTEVLNPKTALFFLAFLPQFVRPENGTVMLQLAVLGIVFVVLG
LFSTVVFAVSAGRLGSFLRRNPTVLKWQGKVVGGIYCALGVRLALQQR
>Mature_208_residues
MIDLSTSIAYTAVVLGFVFIPGPATLLTIARATSSGTKVGIATGAGIAAGDIFHTVMAILGISAIIATSATLFSIVKYIG
AAYLVYLGIRAIIEKTPADPSAGALAISAGKAFRQAVLTEVLNPKTALFFLAFLPQFVRPENGTVMLQLAVLGIVFVVLG
LFSTVVFAVSAGRLGSFLRRNPTVLKWQGKVVGGIYCALGVRLALQQR

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=184, Percent_Identity=28.804347826087, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788099, Length=201, Percent_Identity=28.8557213930348, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786522, Length=159, Percent_Identity=27.6729559748428, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21644; Mature: 21644

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLSTSIAYTAVVLGFVFIPGPATLLTIARATSSGTKVGIATGAGIAAGDIFHTVMAIL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
GISAIIATSATLFSIVKYIGAAYLVYLGIRAIIEKTPADPSAGALAISAGKAFRQAVLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHH
VLNPKTALFFLAFLPQFVRPENGTVMLQLAVLGIVFVVLGLFSTVVFAVSAGRLGSFLRR
HHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPTVLKWQGKVVGGIYCALGVRLALQQR
CCCEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDLSTSIAYTAVVLGFVFIPGPATLLTIARATSSGTKVGIATGAGIAAGDIFHTVMAIL
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
GISAIIATSATLFSIVKYIGAAYLVYLGIRAIIEKTPADPSAGALAISAGKAFRQAVLTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHH
VLNPKTALFFLAFLPQFVRPENGTVMLQLAVLGIVFVVLGLFSTVVFAVSAGRLGSFLRR
HHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NPTVLKWQGKVVGGIYCALGVRLALQQR
CCCEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]