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The map label for this gene is yieH [H]

Identifier: 13476247

GI number: 13476247

Start: 6205535

End: 6206224

Strand: Reverse

Name: yieH [H]

Synonym: mll7519

Alternate gene names: 13476247

Gene position: 6206224-6205535 (Counterclockwise)

Preceding gene: 13476249

Following gene: 13476245

Centisome position: 88.21

GC content: 63.19

Gene sequence:

>690_bases
ATGCCCCAGCCAGACCTTGTCATCTTCGATTGCGACGGCGTGCTCGTCGATTCCGAAATCATCGCCGCGCGGGTCGAGGC
CGAGCTGATAACGCTCGCCGGATATGAAATCTCGGCCGAGGAGATTGCCGAAAGCTATGCGGGCCTGACGTTCAAGGACA
TCCTGATGCGGATCGAGGAGAAGTCCAAGATTCCGTTCCAGGCGTCGCTGATCGACCGCGCCGAAGAGCTCGTCGACCGG
AAACTGCGCAGCGATGTGCGTGCCATCGAGGGCGTGCGCGAAGCGGTCGCCTCGGTCACGGCGCAACGCTGTATCTGCTC
CAATTCACGCTCGGAGCGGATAGAATTCATGCTGGAGAAAGTGCATCTGCTGCCGTTTTTCGCCGGCCGCATCTTCTCGG
CGCTGGAAATACCGAGCAAAAAGACCAAACCCGCGCCGGACGTGTTCCTGTTCGCGGCGGAAAGACTCGGCGCGAACCCA
GCCAACACTTTCGTCATCGAGGATTCCGTGCACGGCGTCGCCGGCGCCCGGGCAGCCGGCATGCGTGTGATCGGCTTCAC
CGGCGCAAGCCACAGCTATCCCGGCCATGCCGACGCGCTGACCGAGGCCGGCGCCGAAACGGTGATCCGCCGCTGGGCAG
AGCTGAAAAGCGTGATCGCGGCGCTGTCGGAATGGTCGGCCGACGCCTGA

Upstream 100 bases:

>100_bases
GCGCGATCGCCTGCCAGGTTTGCGAAGGCCGGGCCATTGGTGTATGCCGCGCCGCCTGAGGCCTTCCTGGCCGCTTCATC
CTTTCTTTGTCCGGATCACC

Downstream 100 bases:

>100_bases
GCACCGTGTGCCCGGCTGGGCACACGCTACGTCCATGGACGCTTAGTTCGTCGTGGCGGCCTTCTTCCTATGAGTCTTCT
TCGGCTTGTCGGTCGTCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPQPDLVIFDCDGVLVDSEIIAARVEAELITLAGYEISAEEIAESYAGLTFKDILMRIEEKSKIPFQASLIDRAEELVDR
KLRSDVRAIEGVREAVASVTAQRCICSNSRSERIEFMLEKVHLLPFFAGRIFSALEIPSKKTKPAPDVFLFAAERLGANP
ANTFVIEDSVHGVAGARAAGMRVIGFTGASHSYPGHADALTEAGAETVIRRWAELKSVIAALSEWSADA

Sequences:

>Translated_229_residues
MPQPDLVIFDCDGVLVDSEIIAARVEAELITLAGYEISAEEIAESYAGLTFKDILMRIEEKSKIPFQASLIDRAEELVDR
KLRSDVRAIEGVREAVASVTAQRCICSNSRSERIEFMLEKVHLLPFFAGRIFSALEIPSKKTKPAPDVFLFAAERLGANP
ANTFVIEDSVHGVAGARAAGMRVIGFTGASHSYPGHADALTEAGAETVIRRWAELKSVIAALSEWSADA
>Mature_228_residues
PQPDLVIFDCDGVLVDSEIIAARVEAELITLAGYEISAEEIAESYAGLTFKDILMRIEEKSKIPFQASLIDRAEELVDRK
LRSDVRAIEGVREAVASVTAQRCICSNSRSERIEFMLEKVHLLPFFAGRIFSALEIPSKKTKPAPDVFLFAAERLGANPA
NTFVIEDSVHGVAGARAAGMRVIGFTGASHSYPGHADALTEAGAETVIRRWAELKSVIAALSEWSADA

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=197, Percent_Identity=29.9492385786802, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1788021, Length=189, Percent_Identity=31.7460317460317, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137324, Length=183, Percent_Identity=26.775956284153, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24893; Mature: 24761

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPDLVIFDCDGVLVDSEIIAARVEAELITLAGYEISAEEIAESYAGLTFKDILMRIEE
CCCCCEEEEECCCEEECHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHH
KSKIPFQASLIDRAEELVDRKLRSDVRAIEGVREAVASVTAQRCICSNSRSERIEFMLEK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VHLLPFFAGRIFSALEIPSKKTKPAPDVFLFAAERLGANPANTFVIEDSVHGVAGARAAG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCC
MRVIGFTGASHSYPGHADALTEAGAETVIRRWAELKSVIAALSEWSADA
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PQPDLVIFDCDGVLVDSEIIAARVEAELITLAGYEISAEEIAESYAGLTFKDILMRIEE
CCCCEEEEECCCEEECHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHH
KSKIPFQASLIDRAEELVDRKLRSDVRAIEGVREAVASVTAQRCICSNSRSERIEFMLEK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VHLLPFFAGRIFSALEIPSKKTKPAPDVFLFAAERLGANPANTFVIEDSVHGVAGARAAG
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCC
MRVIGFTGASHSYPGHADALTEAGAETVIRRWAELKSVIAALSEWSADA
EEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]