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The map label for this gene is aidB [C]

Identifier: 13476195

GI number: 13476195

Start: 6157192

End: 6158961

Strand: Direct

Name: aidB [C]

Synonym: mlr7452

Alternate gene names: 13476195

Gene position: 6157192-6158961 (Clockwise)

Preceding gene: 13476192

Following gene: 13476196

Centisome position: 87.51

GC content: 66.55

Gene sequence:

>1770_bases
ATGTATCGGGCACCGGTCGAGGATATCGCGTTCACGCTGAAGCATGTTGCGGGCATGAAATCCGCCCTTGATGCCGGTAG
GTTCGGCGATCTCGGCGAGGACCTGGTCGACGCCGTCCTTGGCGAGGCCGGCCGTTTCGCCACCGAGGAGGTGGCACCGC
TCTATAAGATCGGCGACGAACACGGTGCGGTGCTCAGGGATGCCGCCGTCACCATGCCGCCCGGCTGGAAGGAGCTTTAT
CGCCGCTGGATCGATGGCGGCTGGAACGCGCTGTCGGGGCCTGAAGACTATGGCGGCCAGGCGCTGCCGACCATGCTGGG
CGTCGCCGCGCTCGAAATGTGGAACTCGGCCGCCATGGCCTTCGGCATCGGCCCGACGCTGACCATGGGCGCGGTCGAAG
CGCTCGACAAGCATGCCTCCGAAGCGCTCAAGGCGAAGTATCTCGCCAAGCTGGTGTCCGGCGAATGGATGGGCACGATG
AATCTGACCGAGCCGCAGGCGGGCTCCGATCTCGCCGCCTTGCGCGCCCGCGCCGAGCCCGCTGGCGACGGCACCTACCG
CATCTTCGGCCAGAAGATCTTCATCACCTATGGCGAGCACGATTTCACCGACAACATCATCCATCTGGTGCTGGCGCGGC
TGCCCGACGCGCCGGCCGGCACGCGCGGCATCTCGCTGTTCCTGGTGCCGAAGTTTTTCGTCAACGACGATGGCTCGCTT
GGCGCCCGCAACGACGTCTTCTGTTCCGGCCTCGAGCACAAGCTCGGCATCCATGCTTCGCCGACCTGCACTATGATTTA
TGGCGACGGTTTCCGGGGCGCCACGCCCGGCGCCATCGGCTGGCTGATCGGCGAGGAAAACAAGGGCCTCGCCTGCATGT
TCACCATGATGAACAATGCCCGCCTCGCCGTCGGCATGCAGGGTGTCGCGGTCGCGGAAGCCGCCACCCAGAAGGCGATC
GCCTATGCCAATGAGCGCCGCCAGGGCAAGGCGGCTGATTACGCCGGCGCCGGCATGGCGCCGATCGTCCATCACCCTGA
CGTGCAGCGCAATCTCCTGACCATGAAGGCGCTGACGCAGACGGCGCGGGCGATCAGCTATTCCTGCGCCCACGCCATCG
ACATGGCACGCGTCTCGGATGGCGATCAGGCGGCGCATTGGCGCGACCGCGCGAACCTGCTCACGCCGCTGGCCAAGGCC
TTTTCGACCGATGTCGGCGTCGAAGTCGCTTCGCTCGGCGTGCAGGTGCATGGCGGCATGGGCTTCATCGAGGAAACGGG
TGCCGCAGCCTTCTACCGCGATGCGCGCATCGCGCCGATCTACGAGGGCACCAACGGCATCCAGGCGATCGATCTGGTCA
CCCGCAAGCTGCCGCTCGGCGGCGGCGAGCATGTGCATGGCTTCATCGGCGAACTCGCCGGGGCCGCCAATGCCGTGCGC
ACCTCGAACCTGCAAGGTTTCGGCCGCACCGCCGATGCGCTCGACGCAGCACTTGGCGACCTGACGCAAGCGACGCGCTT
CCTGCAGAAACTGTCGGCCGACGGCCGGATGGAAGAGGCGCTGGCGGGAGCGACGCCGTATCTCAGGCTGATCTCGCTTG
CCGCTGGCGGCGCCTACCTGGCGCGCGGCGCTCTTGCCGATCAGGATCGCATCGCGCTGTGCCGCTTCTTCGCCGAGAAC
TTGCTCGGCGAGGCACGCGCCTTGAGGGAACGCGTCATCGACGGCGCGGAGAGCCTCGCTGCCGCCGGCAAGACGTTGAT
ATCAGCTTGA

Upstream 100 bases:

>100_bases
TACGTAAAAAGACACTGGGAGACCGCCCAAAGGCGGATGGTTTTGCAGCAGCACCGGCTCTAGGGTCGGCGAGGCCGATG
CATCAGGAGGGTCGAGCGGC

Downstream 100 bases:

>100_bases
ATTCTCACAGCGCTCACCAGGGAAGATGACCGTGACAGACCATATCCTCGTCGAGCGCCAGGGCGCCATCCAGATCATCC
GCATGAACCGCCCGGACAAG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; BCAD; SCAD [H]

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MYRAPVEDIAFTLKHVAGMKSALDAGRFGDLGEDLVDAVLGEAGRFATEEVAPLYKIGDEHGAVLRDAAVTMPPGWKELY
RRWIDGGWNALSGPEDYGGQALPTMLGVAALEMWNSAAMAFGIGPTLTMGAVEALDKHASEALKAKYLAKLVSGEWMGTM
NLTEPQAGSDLAALRARAEPAGDGTYRIFGQKIFITYGEHDFTDNIIHLVLARLPDAPAGTRGISLFLVPKFFVNDDGSL
GARNDVFCSGLEHKLGIHASPTCTMIYGDGFRGATPGAIGWLIGEENKGLACMFTMMNNARLAVGMQGVAVAEAATQKAI
AYANERRQGKAADYAGAGMAPIVHHPDVQRNLLTMKALTQTARAISYSCAHAIDMARVSDGDQAAHWRDRANLLTPLAKA
FSTDVGVEVASLGVQVHGGMGFIEETGAAAFYRDARIAPIYEGTNGIQAIDLVTRKLPLGGGEHVHGFIGELAGAANAVR
TSNLQGFGRTADALDAALGDLTQATRFLQKLSADGRMEEALAGATPYLRLISLAAGGAYLARGALADQDRIALCRFFAEN
LLGEARALRERVIDGAESLAAAGKTLISA

Sequences:

>Translated_589_residues
MYRAPVEDIAFTLKHVAGMKSALDAGRFGDLGEDLVDAVLGEAGRFATEEVAPLYKIGDEHGAVLRDAAVTMPPGWKELY
RRWIDGGWNALSGPEDYGGQALPTMLGVAALEMWNSAAMAFGIGPTLTMGAVEALDKHASEALKAKYLAKLVSGEWMGTM
NLTEPQAGSDLAALRARAEPAGDGTYRIFGQKIFITYGEHDFTDNIIHLVLARLPDAPAGTRGISLFLVPKFFVNDDGSL
GARNDVFCSGLEHKLGIHASPTCTMIYGDGFRGATPGAIGWLIGEENKGLACMFTMMNNARLAVGMQGVAVAEAATQKAI
AYANERRQGKAADYAGAGMAPIVHHPDVQRNLLTMKALTQTARAISYSCAHAIDMARVSDGDQAAHWRDRANLLTPLAKA
FSTDVGVEVASLGVQVHGGMGFIEETGAAAFYRDARIAPIYEGTNGIQAIDLVTRKLPLGGGEHVHGFIGELAGAANAVR
TSNLQGFGRTADALDAALGDLTQATRFLQKLSADGRMEEALAGATPYLRLISLAAGGAYLARGALADQDRIALCRFFAEN
LLGEARALRERVIDGAESLAAAGKTLISA
>Mature_589_residues
MYRAPVEDIAFTLKHVAGMKSALDAGRFGDLGEDLVDAVLGEAGRFATEEVAPLYKIGDEHGAVLRDAAVTMPPGWKELY
RRWIDGGWNALSGPEDYGGQALPTMLGVAALEMWNSAAMAFGIGPTLTMGAVEALDKHASEALKAKYLAKLVSGEWMGTM
NLTEPQAGSDLAALRARAEPAGDGTYRIFGQKIFITYGEHDFTDNIIHLVLARLPDAPAGTRGISLFLVPKFFVNDDGSL
GARNDVFCSGLEHKLGIHASPTCTMIYGDGFRGATPGAIGWLIGEENKGLACMFTMMNNARLAVGMQGVAVAEAATQKAI
AYANERRQGKAADYAGAGMAPIVHHPDVQRNLLTMKALTQTARAISYSCAHAIDMARVSDGDQAAHWRDRANLLTPLAKA
FSTDVGVEVASLGVQVHGGMGFIEETGAAAFYRDARIAPIYEGTNGIQAIDLVTRKLPLGGGEHVHGFIGELAGAANAVR
TSNLQGFGRTADALDAALGDLTQATRFLQKLSADGRMEEALAGATPYLRLISLAAGGAYLARGALADQDRIALCRFFAEN
LLGEARALRERVIDGAESLAAAGKTLISA

Specific function: Has an optimum specificity for 4-carbon length fatty acyl-CoAs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=470, Percent_Identity=25.9574468085106, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=27.9683377308707, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI226958414, Length=379, Percent_Identity=27.9683377308707, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI4501859, Length=408, Percent_Identity=25.9803921568627, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=424, Percent_Identity=27.5943396226415, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI76496475, Length=424, Percent_Identity=27.5943396226415, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=26.5027322404372, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI21361497, Length=435, Percent_Identity=25.5172413793103, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=26.3440860215054, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI87082384, Length=441, Percent_Identity=27.437641723356, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081958, Length=376, Percent_Identity=27.6595744680851, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=422, Percent_Identity=27.9620853080569, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17538396, Length=412, Percent_Identity=27.6699029126214, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=411, Percent_Identity=27.2506082725061, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=364, Percent_Identity=27.4725274725275, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=423, Percent_Identity=25.531914893617, Blast_Score=95, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=404, Percent_Identity=25.4950495049505, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=404, Percent_Identity=25.4950495049505, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=371, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=358, Percent_Identity=28.4916201117318, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=421, Percent_Identity=26.1282660332542, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551932, Length=364, Percent_Identity=25.8241758241758, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=26.530612244898, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71985192, Length=265, Percent_Identity=26.7924528301887, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355753, Length=425, Percent_Identity=26.5882352941176, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21356377, Length=369, Percent_Identity=26.8292682926829, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24666513, Length=410, Percent_Identity=26.5853658536585, Blast_Score=90, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24660351, Length=425, Percent_Identity=27.5294117647059, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24646207, Length=381, Percent_Identity=25.9842519685039, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363737, Length=361, Percent_Identity=24.3767313019391, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 62223; Mature: 62223

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRAPVEDIAFTLKHVAGMKSALDAGRFGDLGEDLVDAVLGEAGRFATEEVAPLYKIGDE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
HGAVLRDAAVTMPPGWKELYRRWIDGGWNALSGPEDYGGQALPTMLGVAALEMWNSAAMA
CCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHE
FGIGPTLTMGAVEALDKHASEALKAKYLAKLVSGEWMGTMNLTEPQAGSDLAALRARAEP
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCC
AGDGTYRIFGQKIFITYGEHDFTDNIIHLVLARLPDAPAGTRGISLFLVPKFFVNDDGSL
CCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCC
GARNDVFCSGLEHKLGIHASPTCTMIYGDGFRGATPGAIGWLIGEENKGLACMFTMMNNA
CCCCCHHHCCCCHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCC
RLAVGMQGVAVAEAATQKAIAYANERRQGKAADYAGAGMAPIVHHPDVQRNLLTMKALTQ
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TARAISYSCAHAIDMARVSDGDQAAHWRDRANLLTPLAKAFSTDVGVEVASLGVQVHGGM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHCCEEEECCC
GFIEETGAAAFYRDARIAPIYEGTNGIQAIDLVTRKLPLGGGEHVHGFIGELAGAANAVR
CCHHHCCCHHEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TSNLQGFGRTADALDAALGDLTQATRFLQKLSADGRMEEALAGATPYLRLISLAAGGAYL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCHHH
ARGALADQDRIALCRFFAENLLGEARALRERVIDGAESLAAAGKTLISA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MYRAPVEDIAFTLKHVAGMKSALDAGRFGDLGEDLVDAVLGEAGRFATEEVAPLYKIGDE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCCC
HGAVLRDAAVTMPPGWKELYRRWIDGGWNALSGPEDYGGQALPTMLGVAALEMWNSAAMA
CCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHE
FGIGPTLTMGAVEALDKHASEALKAKYLAKLVSGEWMGTMNLTEPQAGSDLAALRARAEP
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHCCCC
AGDGTYRIFGQKIFITYGEHDFTDNIIHLVLARLPDAPAGTRGISLFLVPKFFVNDDGSL
CCCCEEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCC
GARNDVFCSGLEHKLGIHASPTCTMIYGDGFRGATPGAIGWLIGEENKGLACMFTMMNNA
CCCCCHHHCCCCHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEECCCC
RLAVGMQGVAVAEAATQKAIAYANERRQGKAADYAGAGMAPIVHHPDVQRNLLTMKALTQ
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TARAISYSCAHAIDMARVSDGDQAAHWRDRANLLTPLAKAFSTDVGVEVASLGVQVHGGM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHCCEEEECCC
GFIEETGAAAFYRDARIAPIYEGTNGIQAIDLVTRKLPLGGGEHVHGFIGELAGAANAVR
CCHHHCCCHHEECCCCEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
TSNLQGFGRTADALDAALGDLTQATRFLQKLSADGRMEEALAGATPYLRLISLAAGGAYL
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHCCCHHH
ARGALADQDRIALCRFFAENLLGEARALRERVIDGAESLAAAGKTLISA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8399220; 7857927 [H]