Click here to switch to the map view.

The map label for this gene is hbpA [H]

Identifier: 13476120

GI number: 13476120

Start: 6081447

End: 6083111

Strand: Reverse

Name: hbpA [H]

Synonym: mll7351

Alternate gene names: 13476120

Gene position: 6083111-6081447 (Counterclockwise)

Preceding gene: 13476121

Following gene: 13476119

Centisome position: 86.46

GC content: 64.2

Gene sequence:

>1665_bases
ATGAGCAAGAATTACCGCATTCTCGACCTGATCCGGCGCAATCGCTCGCCGCTCGAAAACCATCTCATCGACGGTCTCGT
CGACGGCCGTATCAGCCGCCGCGACTTCATTCGCCACGGCAGCCTGCTCGGCCTGTCGCTGCCGCTTCTGGGCGGCATCA
CCACGGCCGCCGGCCTCGGTGGCATGCCGTCGCTCGCCCGCGCCCAGGGCGCGCCCGGCGCGACCATCCGTGTCGGCAGC
AGCGTGCCGGCGGCAACCATCGACCCGGTCACCATCGCCGATGCCGGCGGCCTGCTGATCCTGCAGCAGGTTGCCGAATT
CCTCTGCGTCGACGGCCCCGACCTGGTGCTCAAGCCGGCGCTGGCCGAAAGCTGGAAGCCGAACGACAACGGCACGGTGT
GGACCTTCAAGCTGCGCAAGGGCGTGAAATTCCACTCCGGCGGCGAGATGAAGGCCGACGATGTCGTGGCCAGCATCGAC
CGCCTCGCCGACCCGGCAAACTCGTCCAACGCGCTGTCGGTGTTCACCGGCATCCTGCAGAAGGGCGCCACCAAGAAGGT
CGACGACTACACGGTGGAGTTCCACCTCGACGCGCCGAACGGCAACTTCCCCTACATGGTGTCGTCGGACAACTACAACG
CCGTCATCATCCCGGCGAGCTACAAGGGCGACTACGAGAAAAGCTTCGACGGCACCGGCCCGTTCAAGATCGAAAAATAC
ACGGCCAAGGTCGGCGCCTCCTTCGTCCGCAACGAGGACTATTGGGGCGAAAAGGCACTGCCGGAGCGCACCGAATTCAC
CTTCTTCGCCGACATGCAGCCGCAGATCCTGGCGCTGCAGGGCGGACAGATCGATATCATCAACCAGATGCCGGTGCTCG
CGGGCGTCGCCTTGCTCAATGATCCGAGCGTCGACATCATCAGCCTGAAGTCGGTTGCGCACCAGCAATTGCATCTGCGC
TGCGATTCCGATCCGTTCAAGGACCCGCGCGTGCGCCGCGCCATCGCGCTCAGCATCGATCGCGACAAGCTGGTCGCCGG
CCTGATGAAGGGCCGCGCTTCGGCCGGCAATGACAGCCCGTTCGCGCCTGCCTATCCTTCGACCGATACCAGCGTGCCGC
AGCGCAAGCAGGACATCGCGCAGGCCAAGCAGTTGATGGAAGCGGCCGGCGCCGGCAAGGGTTTCAAGGTGACGCTGACC
ACCGAGCGCTACCTGGAAATTCCCGAATACGCCCAGCTCATCCAGAACTGGGTCAAGGAGATCGGCATCGAGCTCGAGCT
CAACATCCTCGACCAGGGCGCGTATTACGGCGACGCCGTGTTCGGCAAGTCGAACTGGCTGGACTCGGTGATGGGCATCA
CCGACTACGGCCACCGCGGCGTGCCGAATGTCTATCTCGCCGCCCCGCTGAAGAGCGACGGCACCTGGAACGCGGCGCAC
TTCAAGAACAAGGACTACGACACGCTGGCCAACAGCTACATCGCCGCGCTCGACCTCGAGGCGCAGAAGGCCGACGCCGG
CAAGATCCAGAAGCTGCTGCTCGAGGAAACGCCTGTCATTTTCGGCTACTTTTACGACTACCTGACGGCGACGGCGAAGG
GCGTGGCCGGCGTGCAGCCGACCGCCATGTCGCAGCTGTTCCTCGAAAAGGCATCGAAGGCCTAA

Upstream 100 bases:

>100_bases
ACCGACTTCGTTGATGACCGGGACAGGAGAACTCCACGGAATTTCGTCAACCGGAAGTGCATTCTTCAGCCATAAGAAAC
AAGGGGAAAGGGTTAAACCC

Downstream 100 bases:

>100_bases
AACGAAAGGGAAAGCCAATCCTCTAACAGCCAGCTCCCGCGTGGGGGCTGGCTCCACAAGGAGTCTTAGCCATTCTCTCC
TTCTTTGCACGGCGTGTGTC

Product: ABC transporter binding protein

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSKNYRILDLIRRNRSPLENHLIDGLVDGRISRRDFIRHGSLLGLSLPLLGGITTAAGLGGMPSLARAQGAPGATIRVGS
SVPAATIDPVTIADAGGLLILQQVAEFLCVDGPDLVLKPALAESWKPNDNGTVWTFKLRKGVKFHSGGEMKADDVVASID
RLADPANSSNALSVFTGILQKGATKKVDDYTVEFHLDAPNGNFPYMVSSDNYNAVIIPASYKGDYEKSFDGTGPFKIEKY
TAKVGASFVRNEDYWGEKALPERTEFTFFADMQPQILALQGGQIDIINQMPVLAGVALLNDPSVDIISLKSVAHQQLHLR
CDSDPFKDPRVRRAIALSIDRDKLVAGLMKGRASAGNDSPFAPAYPSTDTSVPQRKQDIAQAKQLMEAAGAGKGFKVTLT
TERYLEIPEYAQLIQNWVKEIGIELELNILDQGAYYGDAVFGKSNWLDSVMGITDYGHRGVPNVYLAAPLKSDGTWNAAH
FKNKDYDTLANSYIAALDLEAQKADAGKIQKLLLEETPVIFGYFYDYLTATAKGVAGVQPTAMSQLFLEKASKA

Sequences:

>Translated_554_residues
MSKNYRILDLIRRNRSPLENHLIDGLVDGRISRRDFIRHGSLLGLSLPLLGGITTAAGLGGMPSLARAQGAPGATIRVGS
SVPAATIDPVTIADAGGLLILQQVAEFLCVDGPDLVLKPALAESWKPNDNGTVWTFKLRKGVKFHSGGEMKADDVVASID
RLADPANSSNALSVFTGILQKGATKKVDDYTVEFHLDAPNGNFPYMVSSDNYNAVIIPASYKGDYEKSFDGTGPFKIEKY
TAKVGASFVRNEDYWGEKALPERTEFTFFADMQPQILALQGGQIDIINQMPVLAGVALLNDPSVDIISLKSVAHQQLHLR
CDSDPFKDPRVRRAIALSIDRDKLVAGLMKGRASAGNDSPFAPAYPSTDTSVPQRKQDIAQAKQLMEAAGAGKGFKVTLT
TERYLEIPEYAQLIQNWVKEIGIELELNILDQGAYYGDAVFGKSNWLDSVMGITDYGHRGVPNVYLAAPLKSDGTWNAAH
FKNKDYDTLANSYIAALDLEAQKADAGKIQKLLLEETPVIFGYFYDYLTATAKGVAGVQPTAMSQLFLEKASKA
>Mature_553_residues
SKNYRILDLIRRNRSPLENHLIDGLVDGRISRRDFIRHGSLLGLSLPLLGGITTAAGLGGMPSLARAQGAPGATIRVGSS
VPAATIDPVTIADAGGLLILQQVAEFLCVDGPDLVLKPALAESWKPNDNGTVWTFKLRKGVKFHSGGEMKADDVVASIDR
LADPANSSNALSVFTGILQKGATKKVDDYTVEFHLDAPNGNFPYMVSSDNYNAVIIPASYKGDYEKSFDGTGPFKIEKYT
AKVGASFVRNEDYWGEKALPERTEFTFFADMQPQILALQGGQIDIINQMPVLAGVALLNDPSVDIISLKSVAHQQLHLRC
DSDPFKDPRVRRAIALSIDRDKLVAGLMKGRASAGNDSPFAPAYPSTDTSVPQRKQDIAQAKQLMEAAGAGKGFKVTLTT
ERYLEIPEYAQLIQNWVKEIGIELELNILDQGAYYGDAVFGKSNWLDSVMGITDYGHRGVPNVYLAAPLKSDGTWNAAHF
KNKDYDTLANSYIAALDLEAQKADAGKIQKLLLEETPVIFGYFYDYLTATAKGVAGVQPTAMSQLFLEKASKA

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787052, Length=500, Percent_Identity=25.4, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789966, Length=465, Percent_Identity=26.6666666666667, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081878, Length=517, Percent_Identity=25.3384912959381, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787551, Length=341, Percent_Identity=26.6862170087977, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787762, Length=493, Percent_Identity=23.1237322515213, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789397, Length=510, Percent_Identity=21.9607843137255, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789887, Length=350, Percent_Identity=24, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787495, Length=547, Percent_Identity=23.5831809872029, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60109; Mature: 59978

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNYRILDLIRRNRSPLENHLIDGLVDGRISRRDFIRHGSLLGLSLPLLGGITTAAGLG
CCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHCCC
GMPSLARAQGAPGATIRVGSSVPAATIDPVTIADAGGLLILQQVAEFLCVDGPDLVLKPA
CCCHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEECH
LAESWKPNDNGTVWTFKLRKGVKFHSGGEMKADDVVASIDRLADPANSSNALSVFTGILQ
HHHCCCCCCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KGATKKVDDYTVEFHLDAPNGNFPYMVSSDNYNAVIIPASYKGDYEKSFDGTGPFKIEKY
CCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEHH
TAKVGASFVRNEDYWGEKALPERTEFTFFADMQPQILALQGGQIDIINQMPVLAGVALLN
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEECCCHHHHCEEEEC
DPSVDIISLKSVAHQQLHLRCDSDPFKDPRVRRAIALSIDRDKLVAGLMKGRASAGNDSP
CCCCEEEEHHHHHCCEEEEEECCCCCCCCHHEEEEEEECCHHHHHHHHHHCCCCCCCCCC
FAPAYPSTDTSVPQRKQDIAQAKQLMEAAGAGKGFKVTLTTERYLEIPEYAQLIQNWVKE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHH
IGIELELNILDQGAYYGDAVFGKSNWLDSVMGITDYGHRGVPNVYLAAPLKSDGTWNAAH
CCCEEEEEEEECCCCCCCEECCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHH
FKNKDYDTLANSYIAALDLEAQKADAGKIQKLLLEETPVIFGYFYDYLTATAKGVAGVQP
CCCCCHHHHHHCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
TAMSQLFLEKASKA
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SKNYRILDLIRRNRSPLENHLIDGLVDGRISRRDFIRHGSLLGLSLPLLGGITTAAGLG
CCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHCCC
GMPSLARAQGAPGATIRVGSSVPAATIDPVTIADAGGLLILQQVAEFLCVDGPDLVLKPA
CCCHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCEEECH
LAESWKPNDNGTVWTFKLRKGVKFHSGGEMKADDVVASIDRLADPANSSNALSVFTGILQ
HHHCCCCCCCCCEEEEEECCCCEECCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
KGATKKVDDYTVEFHLDAPNGNFPYMVSSDNYNAVIIPASYKGDYEKSFDGTGPFKIEKY
CCCCCCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCEEEEHH
TAKVGASFVRNEDYWGEKALPERTEFTFFADMQPQILALQGGQIDIINQMPVLAGVALLN
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEEECCCHHHHCEEEEC
DPSVDIISLKSVAHQQLHLRCDSDPFKDPRVRRAIALSIDRDKLVAGLMKGRASAGNDSP
CCCCEEEEHHHHHCCEEEEEECCCCCCCCHHEEEEEEECCHHHHHHHHHHCCCCCCCCCC
FAPAYPSTDTSVPQRKQDIAQAKQLMEAAGAGKGFKVTLTTERYLEIPEYAQLIQNWVKE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHCCHHHHHHHHHHHHH
IGIELELNILDQGAYYGDAVFGKSNWLDSVMGITDYGHRGVPNVYLAAPLKSDGTWNAAH
CCCEEEEEEEECCCCCCCEECCCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCHHH
FKNKDYDTLANSYIAALDLEAQKADAGKIQKLLLEETPVIFGYFYDYLTATAKGVAGVQP
CCCCCHHHHHHCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
TAMSQLFLEKASKA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]