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The map label for this gene is gsiC [H]

Identifier: 13476119

GI number: 13476119

Start: 6080422

End: 6081351

Strand: Reverse

Name: gsiC [H]

Synonym: mll7348

Alternate gene names: 13476119

Gene position: 6081351-6080422 (Counterclockwise)

Preceding gene: 13476120

Following gene: 13476118

Centisome position: 86.43

GC content: 63.12

Gene sequence:

>930_bases
GTGTCGCTGTCGCTGGTTACATTGTTCCTGCTCAGCATCATGGTGTTCCTGGGCGGCCAGGTGCTGCCCGGCAATGTCGG
GCGCGCGATCCTGGGGCCGTTTGCCGACCAGCGCGCGGTCGACGCGCTCAATCATACGCTGGGCGTCGATCGCCCGCTGC
TCACCCAATATGCGACCTGGATCTGGAATTTCATCCGCGGCGACATGGGCACGTCCTACATCTTCCGCTCGCCAGTGGCG
CCGTTCGTCATCGACGCCTTGGGCAATTCGATGAAGCTGGCCGCGGTCGCCTTCGTGCTGGTGGTGCCGATCGGCATCCT
CGGCGGGGTCATCGCGGCGCTCAATCTCAACCGGCCGCTCGACCGCATCATCAGCCTTGGCGGCCTGTCGGTGACGGTGC
TGCCGGAGTTCGTCACCGGCATCATCCTGATCCTGATCTTCGGTGTGTGGCTGCGCTGGCTGCCGATCTCGGCGGCATGG
CCCAAGAACGCCGGCTTCTTTACCCAGCTGTATTATTTGATCCTGCCGTCGGTGCCGCTGTTCCTGGTGCTGTTCGGCTA
TATCGCCCGCATGGCGCGTTCCGGCATGATCGAGGCGCTCGATTCCGACTATACAAGAACGGCGGTACTCAAGGGCCTGC
CCTGGCGCACGGTGATCTGGCGCCATGTGCTGCGCAATGCGCTGCTGCCGACCATCACCGTCATCGCCACCCAGACCGGC
TATCTCATCGGCGGCCTGGTGGTGATCGAGACGCTGTTCCGCTACCAGGGTATCGGTTCGCTGATCTTCACCGCCGCGCG
CGGCAAGGATTTCCCGATGCTGGAATCGGGCATCCTCACCATCGGCATCGTCTATGCCGTGGCGACATTGATCGCCGACT
TCCTCTATTCCGTGCTCAATCCGCGCATCCGGCTGGGGTCAGACCAATGA

Upstream 100 bases:

>100_bases
CCTAAAACGAAAGGGAAAGCCAATCCTCTAACAGCCAGCTCCCGCGTGGGGGCTGGCTCCACAAGGAGTCTTAGCCATTC
TCTCCTTCTTTGCACGGCGT

Downstream 100 bases:

>100_bases
GCGCCGTCCAGACCACCTCTCCCCCGCAAGACGACACGCGCCGGCGCAGCCCCATGGCGGAAGTCTCTTCCTCGCTCATG
CGTTCGCGAACCTTCCTTGT

Product: ABC transporter binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSLSLVTLFLLSIMVFLGGQVLPGNVGRAILGPFADQRAVDALNHTLGVDRPLLTQYATWIWNFIRGDMGTSYIFRSPVA
PFVIDALGNSMKLAAVAFVLVVPIGILGGVIAALNLNRPLDRIISLGGLSVTVLPEFVTGIILILIFGVWLRWLPISAAW
PKNAGFFTQLYYLILPSVPLFLVLFGYIARMARSGMIEALDSDYTRTAVLKGLPWRTVIWRHVLRNALLPTITVIATQTG
YLIGGLVVIETLFRYQGIGSLIFTAARGKDFPMLESGILTIGIVYAVATLIADFLYSVLNPRIRLGSDQ

Sequences:

>Translated_309_residues
MSLSLVTLFLLSIMVFLGGQVLPGNVGRAILGPFADQRAVDALNHTLGVDRPLLTQYATWIWNFIRGDMGTSYIFRSPVA
PFVIDALGNSMKLAAVAFVLVVPIGILGGVIAALNLNRPLDRIISLGGLSVTVLPEFVTGIILILIFGVWLRWLPISAAW
PKNAGFFTQLYYLILPSVPLFLVLFGYIARMARSGMIEALDSDYTRTAVLKGLPWRTVIWRHVLRNALLPTITVIATQTG
YLIGGLVVIETLFRYQGIGSLIFTAARGKDFPMLESGILTIGIVYAVATLIADFLYSVLNPRIRLGSDQ
>Mature_308_residues
SLSLVTLFLLSIMVFLGGQVLPGNVGRAILGPFADQRAVDALNHTLGVDRPLLTQYATWIWNFIRGDMGTSYIFRSPVAP
FVIDALGNSMKLAAVAFVLVVPIGILGGVIAALNLNRPLDRIISLGGLSVTVLPEFVTGIILILIFGVWLRWLPISAAWP
KNAGFFTQLYYLILPSVPLFLVLFGYIARMARSGMIEALDSDYTRTAVLKGLPWRTVIWRHVLRNALLPTITVIATQTGY
LIGGLVVIETLFRYQGIGSLIFTAARGKDFPMLESGILTIGIVYAVATLIADFLYSVLNPRIRLGSDQ

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=298, Percent_Identity=34.8993288590604, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=34.8534201954397, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789965, Length=299, Percent_Identity=31.7725752508361, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789888, Length=261, Percent_Identity=33.3333333333333, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787761, Length=320, Percent_Identity=30.625, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=25.7352941176471, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788504, Length=282, Percent_Identity=23.4042553191489, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33765; Mature: 33634

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSLVTLFLLSIMVFLGGQVLPGNVGRAILGPFADQRAVDALNHTLGVDRPLLTQYATW
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
IWNFIRGDMGTSYIFRSPVAPFVIDALGNSMKLAAVAFVLVVPIGILGGVIAALNLNRPL
HHHHHHHCCCCHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DRIISLGGLSVTVLPEFVTGIILILIFGVWLRWLPISAAWPKNAGFFTQLYYLILPSVPL
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHH
FLVLFGYIARMARSGMIEALDSDYTRTAVLKGLPWRTVIWRHVLRNALLPTITVIATQTG
HHHHHHHHHHHHHCCHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCH
YLIGGLVVIETLFRYQGIGSLIFTAARGKDFPMLESGILTIGIVYAVATLIADFLYSVLN
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRIRLGSDQ
CCCCCCCCC
>Mature Secondary Structure 
SLSLVTLFLLSIMVFLGGQVLPGNVGRAILGPFADQRAVDALNHTLGVDRPLLTQYATW
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHH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CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]