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The map label for this gene is glcK [H]

Identifier: 13476027

GI number: 13476027

Start: 5974045

End: 5975064

Strand: Direct

Name: glcK [H]

Synonym: mlr7234

Alternate gene names: 13476027

Gene position: 5974045-5975064 (Clockwise)

Preceding gene: 13476026

Following gene: 13476028

Centisome position: 84.91

GC content: 70.69

Gene sequence:

>1020_bases
ATGAGCATCGAAGCCGCCCTCGCGATCGATCTTGGCGGCACCGAGCTTCGTGCCGCGCTGGTCGACCGTGACGGCAAGAT
CCTGGCCTTCGCCGCCGTGCCGACGCAGGCACAGGCCGGGCCCGACGTGGTGATCGGCCAGATCGAGGCGCTGGCCGCGA
CCGTGCATGCCGAGGCGCCGGGCCTCGCCATTGTCGGCGTCGGCGTCGGCGCGCCGGGGCCGCTCGACCCGCTGGCCGGC
ATCGCCGTCGGACCGCCGACACTCGCCGGCTGGCAGGATGTACCGCTGGCCGACATCCTCGAGCGCCGCCTCGGCCTGCC
GGTGCGGCTGGAGAACGATGCCAATGCGGCCGCCCTCGGCGAATGGCGCTTCGGTGCCGGCCACGGCGCCCGCTCGCTGG
TCTTCGTCACGGTTTCCACCGGCATCGGCGGCGGTGTCGTTGCCGACGGGCGCATCCTGCATGGCCGCCGTGGGCTGGCC
GCCGAGATCGGCCATATGACCATCACCAACGAGGGCGAGCGCTGCGTGTGCGGCGTCGTCGGCTGCTTCGAGGCCATCGC
CTCGGGCACCGCACTTGGCCGTCGCGCCAACGCCGCGACATCGGCCTTTGACGGCTCGACGTTGCGCCGCCTCTCGGCAA
ATGCCGAGGTCACCGGCCGCCACGTGGTCGAGGCGGCGCGGCTGCAGGACGACCTCGCTTTGGCCCTGCTCGAGGAAGAA
GCACGATGGCTTGGCGTCGGTTTCACCAATTTGCTGCACCTCTATTCGCCCGACGTGCTGGTCGTCGGCGGCGGCATCGC
CAATGGGCTCGACCTGATGCATCCGGTCATCGAGGCGACCATCCGGCAACGCGCCATGCGCGCCTATCGCGACGTGCCGG
TGGTTCAGGCCCAGCTCGGCCGCCACGCCGGGCTGGTCGGCGCCGCCAGCCTTGTCCTGTTCGACGATGGCAGCCTGGCA
GCCCGTATGCCTGTCGGTCCAAGCACGTTTCCTGAAGCGAGGAGGGACTTCAACGGCTGA

Upstream 100 bases:

>100_bases
GTGCCGCCGGTGCGGAGACCGTCGTTCTCGGTTCGCTCGCCTTCGGCGACAAGGATCTCGCCGGCCGCATCGGCTGGCTG
CATGGGCTGAAGGTCGCGGC

Downstream 100 bases:

>100_bases
GCTCATGCTCGACGGCCCGCGCATCAACCAGGTCGATCCGTCCGAGCGCGGCCTTGCCTTGGTGTTCCAGTCCTATGCGC
TCTATCCGCATATGACGGTG

Product: glucose kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSIEAALAIDLGGTELRAALVDRDGKILAFAAVPTQAQAGPDVVIGQIEALAATVHAEAPGLAIVGVGVGAPGPLDPLAG
IAVGPPTLAGWQDVPLADILERRLGLPVRLENDANAAALGEWRFGAGHGARSLVFVTVSTGIGGGVVADGRILHGRRGLA
AEIGHMTITNEGERCVCGVVGCFEAIASGTALGRRANAATSAFDGSTLRRLSANAEVTGRHVVEAARLQDDLALALLEEE
ARWLGVGFTNLLHLYSPDVLVVGGGIANGLDLMHPVIEATIRQRAMRAYRDVPVVQAQLGRHAGLVGAASLVLFDDGSLA
ARMPVGPSTFPEARRDFNG

Sequences:

>Translated_339_residues
MSIEAALAIDLGGTELRAALVDRDGKILAFAAVPTQAQAGPDVVIGQIEALAATVHAEAPGLAIVGVGVGAPGPLDPLAG
IAVGPPTLAGWQDVPLADILERRLGLPVRLENDANAAALGEWRFGAGHGARSLVFVTVSTGIGGGVVADGRILHGRRGLA
AEIGHMTITNEGERCVCGVVGCFEAIASGTALGRRANAATSAFDGSTLRRLSANAEVTGRHVVEAARLQDDLALALLEEE
ARWLGVGFTNLLHLYSPDVLVVGGGIANGLDLMHPVIEATIRQRAMRAYRDVPVVQAQLGRHAGLVGAASLVLFDDGSLA
ARMPVGPSTFPEARRDFNG
>Mature_338_residues
SIEAALAIDLGGTELRAALVDRDGKILAFAAVPTQAQAGPDVVIGQIEALAATVHAEAPGLAIVGVGVGAPGPLDPLAGI
AVGPPTLAGWQDVPLADILERRLGLPVRLENDANAAALGEWRFGAGHGARSLVFVTVSTGIGGGVVADGRILHGRRGLAA
EIGHMTITNEGERCVCGVVGCFEAIASGTALGRRANAATSAFDGSTLRRLSANAEVTGRHVVEAARLQDDLALALLEEEA
RWLGVGFTNLLHLYSPDVLVVGGGIANGLDLMHPVIEATIRQRAMRAYRDVPVVQAQLGRHAGLVGAASLVLFDDGSLAA
RMPVGPSTFPEARRDFNG

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI4885285, Length=319, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI190014632, Length=319, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI298566325, Length=319, Percent_Identity=36.3636363636364, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI298566315, Length=319, Percent_Identity=36.3636363636364, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI298566312, Length=166, Percent_Identity=34.9397590361446, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=310, Percent_Identity=29.3548387096774, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787878, Length=265, Percent_Identity=29.4339622641509, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87081733, Length=317, Percent_Identity=32.1766561514196, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082230, Length=260, Percent_Identity=34.6153846153846, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082127, Length=241, Percent_Identity=24.0663900414938, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787363, Length=324, Percent_Identity=26.8518518518519, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790522, Length=272, Percent_Identity=27.2058823529412, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34813; Mature: 34682

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEAALAIDLGGTELRAALVDRDGKILAFAAVPTQAQAGPDVVIGQIEALAATVHAEAP
CCCCEEEEEECCCHHEEEEEECCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHCCCCC
GLAIVGVGVGAPGPLDPLAGIAVGPPTLAGWQDVPLADILERRLGLPVRLENDANAAALG
CEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCEEEC
EWRFGAGHGARSLVFVTVSTGIGGGVVADGRILHGRRGLAAEIGHMTITNEGERCVCGVV
CCCCCCCCCCCEEEEEEEECCCCCCEEECCEEEECCCCCCEECCEEEEECCCCEEEHHHH
GCFEAIASGTALGRRANAATSAFDGSTLRRLSANAEVTGRHVVEAARLQDDLALALLEEE
HHHHHHHCCCHHCCCCCCHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ARWLGVGFTNLLHLYSPDVLVVGGGIANGLDLMHPVIEATIRQRAMRAYRDVPVVQAQLG
CCEEECCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
RHAGLVGAASLVLFDDGSLAARMPVGPSTFPEARRDFNG
CCCCCEEEEEEEEEECCCEEEECCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
SIEAALAIDLGGTELRAALVDRDGKILAFAAVPTQAQAGPDVVIGQIEALAATVHAEAP
CCCEEEEEECCCHHEEEEEECCCCCEEEEEECCCCCCCCCCEEEHHHHHHHHHHCCCCC
GLAIVGVGVGAPGPLDPLAGIAVGPPTLAGWQDVPLADILERRLGLPVRLENDANAAALG
CEEEEEECCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCEEEC
EWRFGAGHGARSLVFVTVSTGIGGGVVADGRILHGRRGLAAEIGHMTITNEGERCVCGVV
CCCCCCCCCCCEEEEEEEECCCCCCEEECCEEEECCCCCCEECCEEEEECCCCEEEHHHH
GCFEAIASGTALGRRANAATSAFDGSTLRRLSANAEVTGRHVVEAARLQDDLALALLEEE
HHHHHHHCCCHHCCCCCCHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
ARWLGVGFTNLLHLYSPDVLVVGGGIANGLDLMHPVIEATIRQRAMRAYRDVPVVQAQLG
CCEEECCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHC
RHAGLVGAASLVLFDDGSLAARMPVGPSTFPEARRDFNG
CCCCCEEEEEEEEEECCCEEEECCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]