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The map label for this gene is agaR [H]

Identifier: 13476015

GI number: 13476015

Start: 5962542

End: 5963303

Strand: Reverse

Name: agaR [H]

Synonym: mll7220

Alternate gene names: 13476015

Gene position: 5963303-5962542 (Counterclockwise)

Preceding gene: 13476029

Following gene: 13476014

Centisome position: 84.75

GC content: 59.84

Gene sequence:

>762_bases
ATGTTGTCAGAGCAGAGACGCCAATCGATCCTGGGTGAAGTGCAACGAAGCGGACAGGTTCGCATCAAGGACCTGTCAGA
CAATTTTGGCGTGTCGGAAGTCACGGTGCGATCCGACCTCGAGATACTGGACCGCAAGGGACTGCTGACCAAGACGCGTG
GAGGGGCGGTGACCCGGACCACGGATTCGACCACGGCCGCTTTCGCCCGGCGGATGCAAACGAACCTCGATGCAAAGAAA
CGCATCGCCCGGGCAGCGGTGGAACTGTTCGAGGACAACCAATCGGTCATCTTCGACGGCGGCTCGACATTGATGCAGGT
TGCCATGCTGTTACCGCCGCTCAGCAATGTCGTGGTAGCGGCCACGGCGATGAATATCGTTCAGCATCTGATGCATCGGC
CCGGGCTCGACGTTCACATGATCGGCGGCCGGGTCTATCCGGACACGGTGAGCACGCTGATCACCGATGCCGACACGGCT
CTCGGCGGCTTGGTAGCGCATCAGGTCTTTGTTGGAGCGCATGCGATTGACTCGTCACTGGATGTGGTCGACGTGAACGA
AGACATGGCGCGAACGAAACGAAACCTCGTGCGCATGGCCCGCCGCGTTGTCCTTCTTGCGGATTCGAGCAAATGGGGCG
TCAGCGGGACCTCCAAGGCATTTTCGCTGTCGAGCGTCGATGTTGTGATCACCGACGATGGCCTATCCGGCCCGATACGC
AGCCAACTCGATAGGACCGGGGCCAAGGTGATCTATGCCTGA

Upstream 100 bases:

>100_bases
GTTAAATGCAATCTTTCGAAACCTTTCGAATTCGCATATTTTTGGTAGAGTGACCCGAGGCCAGGGCGATCGCCTGGCGC
ATGGAGGCAAGGACAGGGCA

Downstream 100 bases:

>100_bases
CCCTGTCGCGGTTCCTGGCCGCGACGGAAATATCCAATGCGCGCATGACCCACGGGATTCGCATCGGCGGTCGGCCGTTG
ATGTCTGTCATTTTCTCCTC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLSEQRRQSILGEVQRSGQVRIKDLSDNFGVSEVTVRSDLEILDRKGLLTKTRGGAVTRTTDSTTAAFARRMQTNLDAKK
RIARAAVELFEDNQSVIFDGGSTLMQVAMLLPPLSNVVVAATAMNIVQHLMHRPGLDVHMIGGRVYPDTVSTLITDADTA
LGGLVAHQVFVGAHAIDSSLDVVDVNEDMARTKRNLVRMARRVVLLADSSKWGVSGTSKAFSLSSVDVVITDDGLSGPIR
SQLDRTGAKVIYA

Sequences:

>Translated_253_residues
MLSEQRRQSILGEVQRSGQVRIKDLSDNFGVSEVTVRSDLEILDRKGLLTKTRGGAVTRTTDSTTAAFARRMQTNLDAKK
RIARAAVELFEDNQSVIFDGGSTLMQVAMLLPPLSNVVVAATAMNIVQHLMHRPGLDVHMIGGRVYPDTVSTLITDADTA
LGGLVAHQVFVGAHAIDSSLDVVDVNEDMARTKRNLVRMARRVVLLADSSKWGVSGTSKAFSLSSVDVVITDDGLSGPIR
SQLDRTGAKVIYA
>Mature_253_residues
MLSEQRRQSILGEVQRSGQVRIKDLSDNFGVSEVTVRSDLEILDRKGLLTKTRGGAVTRTTDSTTAAFARRMQTNLDAKK
RIARAAVELFEDNQSVIFDGGSTLMQVAMLLPPLSNVVVAATAMNIVQHLMHRPGLDVHMIGGRVYPDTVSTLITDADTA
LGGLVAHQVFVGAHAIDSSLDVVDVNEDMARTKRNLVRMARRVVLLADSSKWGVSGTSKAFSLSSVDVVITDDGLSGPIR
SQLDRTGAKVIYA

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=249, Percent_Identity=31.3253012048193, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1789059, Length=255, Percent_Identity=32.156862745098, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI226510968, Length=238, Percent_Identity=28.9915966386555, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788069, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789829, Length=239, Percent_Identity=27.6150627615063, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082344, Length=248, Percent_Identity=25.8064516129032, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787540, Length=236, Percent_Identity=25.8474576271186, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787063, Length=230, Percent_Identity=24.3478260869565, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790753, Length=225, Percent_Identity=24, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790635, Length=256, Percent_Identity=26.5625, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27317; Mature: 27317

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSEQRRQSILGEVQRSGQVRIKDLSDNFGVSEVTVRSDLEILDRKGLLTKTRGGAVTRT
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHCCCCEEECCCCEEEEC
TDSTTAAFARRMQTNLDAKKRIARAAVELFEDNQSVIFDGGSTLMQVAMLLPPLSNVVVA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHH
ATAMNIVQHLMHRPGLDVHMIGGRVYPDTVSTLITDADTALGGLVAHQVFVGAHAIDSSL
HHHHHHHHHHHHCCCCCEEEECCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVVDVNEDMARTKRNLVRMARRVVLLADSSKWGVSGTSKAFSLSSVDVVITDDGLSGPIR
CEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEECCEEEEEECCCCCCHHH
SQLDRTGAKVIYA
HHHHHCCCEEEEC
>Mature Secondary Structure
MLSEQRRQSILGEVQRSGQVRIKDLSDNFGVSEVTVRSDLEILDRKGLLTKTRGGAVTRT
CCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHHHHCCCCEEECCCCEEEEC
TDSTTAAFARRMQTNLDAKKRIARAAVELFEDNQSVIFDGGSTLMQVAMLLPPLSNVVVA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCHHHHHHH
ATAMNIVQHLMHRPGLDVHMIGGRVYPDTVSTLITDADTALGGLVAHQVFVGAHAIDSSL
HHHHHHHHHHHHCCCCCEEEECCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVVDVNEDMARTKRNLVRMARRVVLLADSSKWGVSGTSKAFSLSSVDVVITDDGLSGPIR
CEEECCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEECCEEEEEECCCCCCHHH
SQLDRTGAKVIYA
HHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]