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The map label for this gene is actR [H]

Identifier: 13475712

GI number: 13475712

Start: 5642066

End: 5642614

Strand: Direct

Name: actR [H]

Synonym: mlr6853

Alternate gene names: 13475712

Gene position: 5642066-5642614 (Clockwise)

Preceding gene: 13475711

Following gene: 13475713

Centisome position: 80.19

GC content: 63.39

Gene sequence:

>549_bases
ATGGAGATGATCATGAGGCCTGATCGATCCCTGTTTATCGTCGAGGACGACGCCACTTTCGCGAAGACGCTGAAGCGCTC
CTTCGAAAAGCGCGACTACGACGTCGTGGTCTGCCACGGCAGGGAAGATCTGCTCGGCGCCCTCGAAACGGCGGTTCCGG
CCTACGCCGTCGTCGATCTCAAGCTTGGCGCCCGCGGCTCCGGGCTGGAATGCGTCAAGCTGCTCAGCGCCCGCGACACG
TCGATGAGGATCGTCGTGCTGACCGGCTTTGCCAGCATCGCCACGGCGGTCGAGGCGATCAAGCTTGGCGCATGTCATTA
CCTGGCCAAGCCCGCCAACACCGATGACATCGAAGCCGCCTTCGGCCGGGCCGAGGGCGATGTTTCGGTCTCGCTGAGCA
GCCGTCCCACCTCGATCAAGAACCTCGAATGGGAGCGTATCCACGAGACGCTCGTCGAGACCGGCTTCAACATCTCCGAA
ACGGCGCGCCGGCTCGGCCTGCATCGGCGCACTTTGGCTCGCAAGCTCGAGAAACGCGTGGTGAGGTAG

Upstream 100 bases:

>100_bases
GTCGTCAACGTGGTCCGAAAGCTGGGAGGCGACTTTTCGGCGCGCAACATGGAGCAGGGGGCCTGTGTTACGCTTTCGCT
GCCGCTCGCGGCGCTGACTG

Downstream 100 bases:

>100_bases
GCTCAACCGTCGTTCTTCAGTGTCGTGGTGCGGCAGGTCTATTCCGCAGCAAACCCAGATAAGCCGCTGGCTTGATCCAT
AATTGTAGTGGGGCTGTAAC

Product: two-component, response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MEMIMRPDRSLFIVEDDATFAKTLKRSFEKRDYDVVVCHGREDLLGALETAVPAYAVVDLKLGARGSGLECVKLLSARDT
SMRIVVLTGFASIATAVEAIKLGACHYLAKPANTDDIEAAFGRAEGDVSVSLSSRPTSIKNLEWERIHETLVETGFNISE
TARRLGLHRRTLARKLEKRVVR

Sequences:

>Translated_182_residues
MEMIMRPDRSLFIVEDDATFAKTLKRSFEKRDYDVVVCHGREDLLGALETAVPAYAVVDLKLGARGSGLECVKLLSARDT
SMRIVVLTGFASIATAVEAIKLGACHYLAKPANTDDIEAAFGRAEGDVSVSLSSRPTSIKNLEWERIHETLVETGFNISE
TARRLGLHRRTLARKLEKRVVR
>Mature_182_residues
MEMIMRPDRSLFIVEDDATFAKTLKRSFEKRDYDVVVCHGREDLLGALETAVPAYAVVDLKLGARGSGLECVKLLSARDT
SMRIVVLTGFASIATAVEAIKLGACHYLAKPANTDDIEAAFGRAEGDVSVSLSSRPTSIKNLEWERIHETLVETGFNISE
TARRLGLHRRTLARKLEKRVVR

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20162; Mature: 20162

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMIMRPDRSLFIVEDDATFAKTLKRSFEKRDYDVVVCHGREDLLGALETAVPAYAVVDL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEEEE
KLGARGSGLECVKLLSARDTSMRIVVLTGFASIATAVEAIKLGACHYLAKPANTDDIEAA
EECCCCCCHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FGRAEGDVSVSLSSRPTSIKNLEWERIHETLVETGFNISETARRLGLHRRTLARKLEKRV
HCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VR
CC
>Mature Secondary Structure
MEMIMRPDRSLFIVEDDATFAKTLKRSFEKRDYDVVVCHGREDLLGALETAVPAYAVVDL
CCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCEEEEEE
KLGARGSGLECVKLLSARDTSMRIVVLTGFASIATAVEAIKLGACHYLAKPANTDDIEAA
EECCCCCCHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FGRAEGDVSVSLSSRPTSIKNLEWERIHETLVETGFNISETARRLGLHRRTLARKLEKRV
HCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]