Click here to switch to the map view.

The map label for this gene is fppS [H]

Identifier: 13475328

GI number: 13475328

Start: 5193096

End: 5194061

Strand: Direct

Name: fppS [H]

Synonym: mlr6368

Alternate gene names: 13475328

Gene position: 5193096-5194061 (Clockwise)

Preceding gene: 13475327

Following gene: 13475329

Centisome position: 73.81

GC content: 68.01

Gene sequence:

>966_bases
ATGCAGACCGATTCCACGCTACACGACGACGCGCAGGCGCGCGGCGCATCCGGCAGGCTGCCGTCGGAGATCTGGATGCA
GGACGGCGTAAGGCGGGTCGAACAGGCGCTGGCGCGTCTTCTCTGCGCCGAAGACGACGGTGAGACCGAGCTGATGGCGG
CGATGCGCTACGCCACCTTGCATGGCGGAAAGCGCACCCGCGCCTTGCTCTGTCTGGCTACCGGCGCACTGGCCGACACG
CCGGCGCCCATGCTCGACGATGTCGGCGCCGCCATCGAGATGATGCACGCCTGTACCCTGGTCCACGACGACCTGCCCGC
AATGGACGATGACGTGCTTCGCCGCGGCCTTCCGACCGTGCACGTCAAGTTCGGCGAAGCCACTGCGATCCTGGTCGGCG
ATGCGCTGCAGGCGCACGCCTTCCTGACCCTGGCGAGCCTGGATGCGCCGAGCGACAACCGTATCGCGCTCGTGCGCGAA
CTGGCGCAGGCGGTGTCCGCCGAGGGTGCCGCAGGCGGGCAGGCCATGGATCTGTCGCTGGTAGGAAAGCACGTCGAGCT
GGACAGGATCGTGGCGATGCACCGGATGAAGAGCGGAGCACTAGTGCGCGCGTCCGTTCGCATGGGCGCGCTATGCGCCA
TCGCGGAGGATGCCGCCCACGCTGCGCTGTACTGTGCGCTCGATCGCTACTCCGCCTGTTTCGGCCTGGCGTTGCAGGTG
GTCGACGACATTCTCGACGCGACAGCGGATACCGCGACGTTGGGCAAGACCCCCGGCAAGGACGCGGCGGCGCAGAAGCC
GACCTGTGCGTCGATCATGGGGCTGCAGGCAGCGCGCCAGTTGGCGCTGGATCTGTTGCGCGACGCCGGGGAGGCCATCC
CCCCGCTGGGAACGCGTGCGGAACGGTTGGCGCAGATGCTGCAACGGGCCAACGCGTATCTGTTCAAGCACGCGCCATGC
GCATGA

Upstream 100 bases:

>100_bases
CGAGGCAGCTACTCGGCGCGCGCGCTCGGTGCGACCCCGCCAACACCGCGGCGGCTCGGACGCTCGCCGTGGCCGTGCCA
GATACAAGGACATGAACGAC

Downstream 100 bases:

>100_bases
GCGCGCCCGTCCGCATGGAGTCGCCCCTGTGCCGCTGCGATCGATCGGCCGGCGTGAGCGGTGCATGCTGCACTGTGTCC
AAGTCGGCGGCGGCGATCGC

Product: geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MQTDSTLHDDAQARGASGRLPSEIWMQDGVRRVEQALARLLCAEDDGETELMAAMRYATLHGGKRTRALLCLATGALADT
PAPMLDDVGAAIEMMHACTLVHDDLPAMDDDVLRRGLPTVHVKFGEATAILVGDALQAHAFLTLASLDAPSDNRIALVRE
LAQAVSAEGAAGGQAMDLSLVGKHVELDRIVAMHRMKSGALVRASVRMGALCAIAEDAAHAALYCALDRYSACFGLALQV
VDDILDATADTATLGKTPGKDAAAQKPTCASIMGLQAARQLALDLLRDAGEAIPPLGTRAERLAQMLQRANAYLFKHAPC
A

Sequences:

>Translated_321_residues
MQTDSTLHDDAQARGASGRLPSEIWMQDGVRRVEQALARLLCAEDDGETELMAAMRYATLHGGKRTRALLCLATGALADT
PAPMLDDVGAAIEMMHACTLVHDDLPAMDDDVLRRGLPTVHVKFGEATAILVGDALQAHAFLTLASLDAPSDNRIALVRE
LAQAVSAEGAAGGQAMDLSLVGKHVELDRIVAMHRMKSGALVRASVRMGALCAIAEDAAHAALYCALDRYSACFGLALQV
VDDILDATADTATLGKTPGKDAAAQKPTCASIMGLQAARQLALDLLRDAGEAIPPLGTRAERLAQMLQRANAYLFKHAPC
A
>Mature_321_residues
MQTDSTLHDDAQARGASGRLPSEIWMQDGVRRVEQALARLLCAEDDGETELMAAMRYATLHGGKRTRALLCLATGALADT
PAPMLDDVGAAIEMMHACTLVHDDLPAMDDDVLRRGLPTVHVKFGEATAILVGDALQAHAFLTLASLDAPSDNRIALVRE
LAQAVSAEGAAGGQAMDLSLVGKHVELDRIVAMHRMKSGALVRASVRMGALCAIAEDAAHAALYCALDRYSACFGLALQV
VDDILDATADTATLGKTPGKDAAAQKPTCASIMGLQAARQLALDLLRDAGEAIPPLGTRAERLAQMLQRANAYLFKHAPC
A

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=274, Percent_Identity=49.2700729927007, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789578, Length=216, Percent_Identity=28.2407407407407, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 33840; Mature: 33840

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDSTLHDDAQARGASGRLPSEIWMQDGVRRVEQALARLLCAEDDGETELMAAMRYATL
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
HGGKRTRALLCLATGALADTPAPMLDDVGAAIEMMHACTLVHDDLPAMDDDVLRRGLPTV
CCCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEE
HVKFGEATAILVGDALQAHAFLTLASLDAPSDNRIALVRELAQAVSAEGAAGGQAMDLSL
EEEECCEEEEEECCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEHHH
VGKHVELDRIVAMHRMKSGALVRASVRMGALCAIAEDAAHAALYCALDRYSACFGLALQV
HCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDDILDATADTATLGKTPGKDAAAQKPTCASIMGLQAARQLALDLLRDAGEAIPPLGTRA
HHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ERLAQMLQRANAYLFKHAPCA
HHHHHHHHHHCHHEECCCCCC
>Mature Secondary Structure
MQTDSTLHDDAQARGASGRLPSEIWMQDGVRRVEQALARLLCAEDDGETELMAAMRYATL
CCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
HGGKRTRALLCLATGALADTPAPMLDDVGAAIEMMHACTLVHDDLPAMDDDVLRRGLPTV
CCCCHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEE
HVKFGEATAILVGDALQAHAFLTLASLDAPSDNRIALVRELAQAVSAEGAAGGQAMDLSL
EEEECCEEEEEECCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEHHH
VGKHVELDRIVAMHRMKSGALVRASVRMGALCAIAEDAAHAALYCALDRYSACFGLALQV
HCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDDILDATADTATLGKTPGKDAAAQKPTCASIMGLQAARQLALDLLRDAGEAIPPLGTRA
HHHHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ERLAQMLQRANAYLFKHAPCA
HHHHHHHHHHCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9655913; 12597275 [H]