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The map label for this gene is soxB [H]

Identifier: 13475214

GI number: 13475214

Start: 5057856

End: 5059106

Strand: Reverse

Name: soxB [H]

Synonym: mll6240

Alternate gene names: 13475214

Gene position: 5059106-5057856 (Counterclockwise)

Preceding gene: 13475216

Following gene: 13475213

Centisome position: 71.9

GC content: 62.91

Gene sequence:

>1251_bases
ATGCGATACTCGGCTCTCTCGATCTTGCTCAACGGCCTTCGCGGCAACACCGGCTGGGGCCCCGCCTGGCGCGCGCCGGA
ACCGAAGTCCCATTACGATGTCATCATCGTCGGCGGCGGGGGCCACGGCCTTGCGACCGCCTATTATCTCGGCAAGGAAT
TCGGCATCACCAACGTCGCAGTACTGGAAAAAGGCTATATCGGCGGCGGAAACGTCGGCCGCAACACGACGATCATCCGT
TCGAATTACTTGCTGCCGGGCAATAATCCCTTCTACGAACTGTCTTTGAAGCTCTGGGAAGGCCTGGAGCAGGACTTCAA
TTTCAACGCCATGATTTCCCAGCGCGGCGTGCTCAATCTCTACCATTCCGATGCGCAGCGCGACGCCTATACGCGGCGCG
GAAATGCCATGCTGCTGCACGGCGTCGATGCCGAACTGCTCAACCGCGAGGAGGTGCGCGCCAAACTGCCCTTCCTTGAT
TTCGACAATGCCCGCTTTCCCATCCAGGGCGGCCTTCTGCAGCGGCGTGGCGGCACGGTGCGGCATGATGCTGTGGCCTG
GGGCTATGCGCGGGGCGCCGACAGCCGCGGCGTCGACATCATCCAACATTGCGAGGTGACCGGCATCCGCCGGGAAAACG
GCAAGGTCGTTGGCGTCGAGACCACGCGCGGCTTCATCGGCTGCGGCAAGCTGGCACTCGCGGCTGCCGGCAATTCCTCC
CGTGTTGCCGAAATGGCCGATATCAAGCTGCCGCTTGAAAGCCATGTGCTGCAGGCCTTCGTCTCCGAGGGCCTAAAACC
CTTCATCGATTGCGTCGTCACCTTCGGCGCGGGGCATTTCTATGTCTCGCAGTCGGACAAGGGAGGGCTGGTCTTCGGCG
GCGACATCGACGGCTATAATTCCTATGCCCAGCGCGGCAATCTCGCCACCGTCGAGCATGTCGCCGAGGCGGGCAAGGCG
ATGATCCCAGGCATTTCCCGTGTACGTGTGCTGCGTTCCTGGGGCGGCGTCATGGACATGTCGATGGACGGCTCGCCGAT
CATCGACCGCACCCACATCGACAATCTCTACCTCAATGCCGGCTGGTGCTATGGCGGCTTCAAGGCCACGCCCGCATCCG
GCCTCTGCTTTGCGCACCTGATCGCACGGGGCACGCCGCACGAAACCGCTCGCGCCTTCCGGCTCGACCGCTTCGCGCGT
GGCCATATCCTCGACGAAAAGGGCCAGGGCGCCCAGCCCAACCTTCACTGA

Upstream 100 bases:

>100_bases
CGTCATGTCCGATCTATATAATAAACCGTCCCATAGGTGGAACTGAAATCTGGTCGACGGGCATAGGTTGACCCAAGTCC
CAGCTTGGATATGGCCAGCT

Downstream 100 bases:

>100_bases
TTTCCAGGATACCTGAACATGGCAAGCCTTATCCCATGCCCTCATTGCGGCTCTCGACCCAAAGAGGAATTCACCGTGAA
GGGCGCGGCAGTTGCCCGAC

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MRYSALSILLNGLRGNTGWGPAWRAPEPKSHYDVIIVGGGGHGLATAYYLGKEFGITNVAVLEKGYIGGGNVGRNTTIIR
SNYLLPGNNPFYELSLKLWEGLEQDFNFNAMISQRGVLNLYHSDAQRDAYTRRGNAMLLHGVDAELLNREEVRAKLPFLD
FDNARFPIQGGLLQRRGGTVRHDAVAWGYARGADSRGVDIIQHCEVTGIRRENGKVVGVETTRGFIGCGKLALAAAGNSS
RVAEMADIKLPLESHVLQAFVSEGLKPFIDCVVTFGAGHFYVSQSDKGGLVFGGDIDGYNSYAQRGNLATVEHVAEAGKA
MIPGISRVRVLRSWGGVMDMSMDGSPIIDRTHIDNLYLNAGWCYGGFKATPASGLCFAHLIARGTPHETARAFRLDRFAR
GHILDEKGQGAQPNLH

Sequences:

>Translated_416_residues
MRYSALSILLNGLRGNTGWGPAWRAPEPKSHYDVIIVGGGGHGLATAYYLGKEFGITNVAVLEKGYIGGGNVGRNTTIIR
SNYLLPGNNPFYELSLKLWEGLEQDFNFNAMISQRGVLNLYHSDAQRDAYTRRGNAMLLHGVDAELLNREEVRAKLPFLD
FDNARFPIQGGLLQRRGGTVRHDAVAWGYARGADSRGVDIIQHCEVTGIRRENGKVVGVETTRGFIGCGKLALAAAGNSS
RVAEMADIKLPLESHVLQAFVSEGLKPFIDCVVTFGAGHFYVSQSDKGGLVFGGDIDGYNSYAQRGNLATVEHVAEAGKA
MIPGISRVRVLRSWGGVMDMSMDGSPIIDRTHIDNLYLNAGWCYGGFKATPASGLCFAHLIARGTPHETARAFRLDRFAR
GHILDEKGQGAQPNLH
>Mature_416_residues
MRYSALSILLNGLRGNTGWGPAWRAPEPKSHYDVIIVGGGGHGLATAYYLGKEFGITNVAVLEKGYIGGGNVGRNTTIIR
SNYLLPGNNPFYELSLKLWEGLEQDFNFNAMISQRGVLNLYHSDAQRDAYTRRGNAMLLHGVDAELLNREEVRAKLPFLD
FDNARFPIQGGLLQRRGGTVRHDAVAWGYARGADSRGVDIIQHCEVTGIRRENGKVVGVETTRGFIGCGKLALAAAGNSS
RVAEMADIKLPLESHVLQAFVSEGLKPFIDCVVTFGAGHFYVSQSDKGGLVFGGDIDGYNSYAQRGNLATVEHVAEAGKA
MIPGISRVRVLRSWGGVMDMSMDGSPIIDRTHIDNLYLNAGWCYGGFKATPASGLCFAHLIARGTPHETARAFRLDRFAR
GHILDEKGQGAQPNLH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=400, Percent_Identity=24.25, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21361378, Length=400, Percent_Identity=24.25, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI24797151, Length=363, Percent_Identity=22.038567493113, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571104, Length=391, Percent_Identity=25.8312020460358, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45190; Mature: 45190

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYSALSILLNGLRGNTGWGPAWRAPEPKSHYDVIIVGGGGHGLATAYYLGKEFGITNVA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEE
VLEKGYIGGGNVGRNTTIIRSNYLLPGNNPFYELSLKLWEGLEQDFNFNAMISQRGVLNL
EEECCCCCCCCCCCCEEEEEECEECCCCCCEEEEEEHHHHCHHHCCCCEEEECCCCEEEE
YHSDAQRDAYTRRGNAMLLHGVDAELLNREEVRAKLPFLDFDNARFPIQGGLLQRRGGTV
ECCCHHHHHHHCCCCEEEEECCCHHHHCHHHHHHHCCEEECCCCCCCCCCCCHHCCCCCE
RHDAVAWGYARGADSRGVDIIQHCEVTGIRRENGKVVGVETTRGFIGCGKLALAAAGNSS
EECCEEEECCCCCCCCCCHHHHHCCEEEEEECCCEEEEEECCCCEEECCCEEEEECCCCC
RVAEMADIKLPLESHVLQAFVSEGLKPFIDCVVTFGAGHFYVSQSDKGGLVFGGDIDGYN
CEEEHHHEECCHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCH
SYAQRGNLATVEHVAEAGKAMIPGISRVRVLRSWGGVMDMSMDGSPIIDRTHIDNLYLNA
HHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCEEEEECCEEEEEC
GWCYGGFKATPASGLCFAHLIARGTPHETARAFRLDRFARGHILDEKGQGAQPNLH
EEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MRYSALSILLNGLRGNTGWGPAWRAPEPKSHYDVIIVGGGGHGLATAYYLGKEFGITNVA
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEE
VLEKGYIGGGNVGRNTTIIRSNYLLPGNNPFYELSLKLWEGLEQDFNFNAMISQRGVLNL
EEECCCCCCCCCCCCEEEEEECEECCCCCCEEEEEEHHHHCHHHCCCCEEEECCCCEEEE
YHSDAQRDAYTRRGNAMLLHGVDAELLNREEVRAKLPFLDFDNARFPIQGGLLQRRGGTV
ECCCHHHHHHHCCCCEEEEECCCHHHHCHHHHHHHCCEEECCCCCCCCCCCCHHCCCCCE
RHDAVAWGYARGADSRGVDIIQHCEVTGIRRENGKVVGVETTRGFIGCGKLALAAAGNSS
EECCEEEECCCCCCCCCCHHHHHCCEEEEEECCCEEEEEECCCCEEECCCEEEEECCCCC
RVAEMADIKLPLESHVLQAFVSEGLKPFIDCVVTFGAGHFYVSQSDKGGLVFGGDIDGYN
CEEEHHHEECCHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCCH
SYAQRGNLATVEHVAEAGKAMIPGISRVRVLRSWGGVMDMSMDGSPIIDRTHIDNLYLNA
HHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCCCCCEEEEECCEEEEEC
GWCYGGFKATPASGLCFAHLIARGTPHETARAFRLDRFARGHILDEKGQGAQPNLH
EEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]