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The map label for this gene is dinF [H]

Identifier: 13475186

GI number: 13475186

Start: 5025176

End: 5026516

Strand: Reverse

Name: dinF [H]

Synonym: mll6207

Alternate gene names: 13475186

Gene position: 5026516-5025176 (Counterclockwise)

Preceding gene: 13475189

Following gene: 13475185

Centisome position: 71.44

GC content: 57.57

Gene sequence:

>1341_bases
GTGGCAAAGAAGACGTCGATTCAAGGCTCCGCGCCATTCAGGGTAACCCATCGGCAGGTACTGGAAATTGCCATTCCGAT
GACGCTCGCATATCTCACGACGCCGCTGCTTGGCCTCGTTGGTACGGCCGTAGTTGGCCGGTTCGGTGATGCAGCTTTAG
TTGGGGGTCTTGCTGCCGGAGCGGCGGTCTTCGACATCGTTTTCGCAGCCTTCAATTTCTTGCGCTCCGGTACGACAGCA
CTAGTCGCCCAGGCTTTCGGGAGAAACGACGCTCTGGAAGAGAAGGCGGTCTTCTGGCGGGCGCTTGTCATCGCTGCAAT
TTCTGGCCTGGGCCTGGTCTTGTTTTCGCCGTTGATTGCCGTGGTAGGCGAATGGTTCATGAACACGGAACCGCGGGTGA
CCGCCGCGATGGATTTGTACATTCGCGTCCGCCTTATCGCAGCACCTGCTGCCTTCATTAACTATACAATTCTCGGCTAC
CTCCTAGGCAGCGGCAATTCGGTCCTCGGCCTTCTGATGCAACTTCTCCTGAACGGGATGAATGTCGCCCTCTCGATCCT
TCTATGTCTTTATCTCGGTTGGGGTATTTCAGGCGTCGCCTGGGGGACTGTCTTCAGTGAAGGCGTCGCCATGGTCGCCG
GAATGACAATTCTCTTGGTCCGCTTCCGCGCGATGCCGAAAATGTCGCGACAGCTTACGTTCAACATGGTGGCAATAGGG
CGAATGCTTTACGTCAGCGGCGACATAGTGACCCCTTCTTGCATGCTCCTGGGTGCCTATATGCTGTTCACGAGACAGAG
CGCCCAGCTTGGCGCGCTGACCCTCGCCACTAATGCGGTCCTGATGCATATCTTCCTGGTCGCGGCCTATTTTCTTGATG
GGTTTGGAGCCGCGGCCGAGCAACTCGTCGGGCGAGCTCTTGGTGCCCGTTATCAGCCGGCATTTTCGCAAGCCATTAAG
CTGACCGCAGGCTGGGGACTTGCGGTTGCGGTTCTTGCGAGCGTTGTGATCTTCGCGTTTGGTGAACACCTCATTGGCGC
CATAACAAAGGCTGCTGATGTGCGAGCCGAGGCGGCTCTCTATCTTCCTTGGGCGGCCTTCGCGGCACCGAGCGGCGCGC
TCGCGCTTCAGATGACCGGCGTCTTCGTGGGGGCAACTTGGTGGCTCGACGTGCGCAATATGATGCTCCTATCCTTCGTG
GCCTTTATCACAACTTTGTTTGCATTCGGCCAGTTGTTCGGCAATCACGGACTTTGGGCCGCTTTTCACATTTTTCAACT
GCTGCGAGGGCTAAGCTTGTTGCTGGTACTGCGCCGCCGCGCCAGCACCGTCTTTGCGTAG

Upstream 100 bases:

>100_bases
TCGAAATGGCCTCCCAAGAATCGCAAGTTGCGGAAACTGTCCAGGGGCCGCTCAGCACACCGATTGTAATCAAAATGCAT
CAATCCAGCAGGAGCCGAAC

Downstream 100 bases:

>100_bases
ACCAGTCGATATGACGTCCGTCGCTAAGGGAGATGTGGGCTGTGTTGCAAAGAGTTTAATAATGGGTTTGCAGTGGAAGA
TCGACGCGGTGGACCAAGTT

Product: DNA-damage-inducible protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MAKKTSIQGSAPFRVTHRQVLEIAIPMTLAYLTTPLLGLVGTAVVGRFGDAALVGGLAAGAAVFDIVFAAFNFLRSGTTA
LVAQAFGRNDALEEKAVFWRALVIAAISGLGLVLFSPLIAVVGEWFMNTEPRVTAAMDLYIRVRLIAAPAAFINYTILGY
LLGSGNSVLGLLMQLLLNGMNVALSILLCLYLGWGISGVAWGTVFSEGVAMVAGMTILLVRFRAMPKMSRQLTFNMVAIG
RMLYVSGDIVTPSCMLLGAYMLFTRQSAQLGALTLATNAVLMHIFLVAAYFLDGFGAAAEQLVGRALGARYQPAFSQAIK
LTAGWGLAVAVLASVVIFAFGEHLIGAITKAADVRAEAALYLPWAAFAAPSGALALQMTGVFVGATWWLDVRNMMLLSFV
AFITTLFAFGQLFGNHGLWAAFHIFQLLRGLSLLLVLRRRASTVFA

Sequences:

>Translated_446_residues
MAKKTSIQGSAPFRVTHRQVLEIAIPMTLAYLTTPLLGLVGTAVVGRFGDAALVGGLAAGAAVFDIVFAAFNFLRSGTTA
LVAQAFGRNDALEEKAVFWRALVIAAISGLGLVLFSPLIAVVGEWFMNTEPRVTAAMDLYIRVRLIAAPAAFINYTILGY
LLGSGNSVLGLLMQLLLNGMNVALSILLCLYLGWGISGVAWGTVFSEGVAMVAGMTILLVRFRAMPKMSRQLTFNMVAIG
RMLYVSGDIVTPSCMLLGAYMLFTRQSAQLGALTLATNAVLMHIFLVAAYFLDGFGAAAEQLVGRALGARYQPAFSQAIK
LTAGWGLAVAVLASVVIFAFGEHLIGAITKAADVRAEAALYLPWAAFAAPSGALALQMTGVFVGATWWLDVRNMMLLSFV
AFITTLFAFGQLFGNHGLWAAFHIFQLLRGLSLLLVLRRRASTVFA
>Mature_445_residues
AKKTSIQGSAPFRVTHRQVLEIAIPMTLAYLTTPLLGLVGTAVVGRFGDAALVGGLAAGAAVFDIVFAAFNFLRSGTTAL
VAQAFGRNDALEEKAVFWRALVIAAISGLGLVLFSPLIAVVGEWFMNTEPRVTAAMDLYIRVRLIAAPAAFINYTILGYL
LGSGNSVLGLLMQLLLNGMNVALSILLCLYLGWGISGVAWGTVFSEGVAMVAGMTILLVRFRAMPKMSRQLTFNMVAIGR
MLYVSGDIVTPSCMLLGAYMLFTRQSAQLGALTLATNAVLMHIFLVAAYFLDGFGAAAEQLVGRALGARYQPAFSQAIKL
TAGWGLAVAVLASVVIFAFGEHLIGAITKAADVRAEAALYLPWAAFAAPSGALALQMTGVFVGATWWLDVRNMMLLSFVA
FITTLFAFGQLFGNHGLWAAFHIFQLLRGLSLLLVLRRRASTVFA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=440, Percent_Identity=31.8181818181818, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47522; Mature: 47391

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKKTSIQGSAPFRVTHRQVLEIAIPMTLAYLTTPLLGLVGTAVVGRFGDAALVGGLAAG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AAVFDIVFAAFNFLRSGTTALVAQAFGRNDALEEKAVFWRALVIAAISGLGLVLFSPLIA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVGEWFMNTEPRVTAAMDLYIRVRLIAAPAAFINYTILGYLLGSGNSVLGLLMQLLLNGM
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCH
NVALSILLCLYLGWGISGVAWGTVFSEGVAMVAGMTILLVRFRAMPKMSRQLTFNMVAIG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
RMLYVSGDIVTPSCMLLGAYMLFTRQSAQLGALTLATNAVLMHIFLVAAYFLDGFGAAAE
HHHEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QLVGRALGARYQPAFSQAIKLTAGWGLAVAVLASVVIFAFGEHLIGAITKAADVRAEAAL
HHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
YLPWAAFAAPSGALALQMTGVFVGATWWLDVRNMMLLSFVAFITTLFAFGQLFGNHGLWA
EECHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AFHIFQLLRGLSLLLVLRRRASTVFA
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]