BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is fabG [C]

Identifier: 13474798

GI number: 13474798

Start: 4646967

End: 4647719

Strand: Reverse

Name: fabG [C]

Synonym: mll5766

Alternate gene names: 13474798

Gene position: 4647719-4646967 (Counterclockwise)

Preceding gene: 13474799

Following gene: 13474797

Centisome position: 66.06

GC content: 63.21

Gene sequence:

>753_bases
ATGTTGCTGAAGGGCAAGGCCGTGGTGATTTCGGGTGCCGCGAGCCCCCGGGGAATTGGCCGCTCCACGGCAACGCTGAT
GGCGGAGCAAGGCGCGCGCATAGCTATTCTTGACCTTGATGAGGAACAAGCCCGTGACGCCGCCGCGTCGCTTGGACCCG
AGCACATCGGCCTCGCCTGCAATGTCGCCGACCTCGATTCCTGCAAGAGGGCTGCGGCAGAAGTGACCGAAGCGTTCGGA
AGGGTCGAGGTGTTATGCAACATTGCCGGGATCACGCAGCCCGTAAAGACACTGGACATCGGTCCGGCCGACTGGGACCG
CATCCTCGATGTCAATCTGCGCGGCGTGCTCTATCTCAGCCAGGCCTTCATCCCGCATATGCGTGAAAATGGCGGCGGCT
CGATCATCTGCATGTCGTCGGTTTCAGCGCAACGCGGCGGCGGCATCTTCGGTGGCCCGCATTACTCAGCCGCCAAGGCG
GGTGTGCTCGGCCTCGCCAAGGCCATGGCACGCGAATTCGGGCCTGACGGCATTCGCATCAACTGCGTCACGCCTGGCCT
GATCCAGACCGACATAACCGGCGGCAAACTGACCGATGCCATGCGCGCTGACATCATCAAGGGTATCCCGCTCAGTCGCC
TGGGCGATGCGCGTGACGTGGCGGGCGCCTACCTCTTCCTCGCCTCCGATCTGGCCAGCTACATCACCGGTGCCGTGATC
GACGTCAATGGGGGGATGCTGATCCATGGCTGA

Upstream 100 bases:

>100_bases
CCGCACGAGGAGCGGCTTGCGTTGTTCCATGACAACGCAGCCCGGCACTACCGGCTCTAGATCATCCGCCGAAACAATTG
AAACAGCAGGAGACTTTGAC

Downstream 100 bases:

>100_bases
CGGGACAACGGAATTCGAGATGCCACGCGCGGGCAGCAATGTCAGCCTTGCCGAACGCGCCTATCGCATCCGTCGACATG
CCGTGCGCATGGGCGAAGTC

Product: short-chain type dehydrogenase/reductase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLLKGKAVVISGAASPRGIGRSTATLMAEQGARIAILDLDEEQARDAAASLGPEHIGLACNVADLDSCKRAAAEVTEAFG
RVEVLCNIAGITQPVKTLDIGPADWDRILDVNLRGVLYLSQAFIPHMRENGGGSIICMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMAREFGPDGIRINCVTPGLIQTDITGGKLTDAMRADIIKGIPLSRLGDARDVAGAYLFLASDLASYITGAVI
DVNGGMLIHG

Sequences:

>Translated_250_residues
MLLKGKAVVISGAASPRGIGRSTATLMAEQGARIAILDLDEEQARDAAASLGPEHIGLACNVADLDSCKRAAAEVTEAFG
RVEVLCNIAGITQPVKTLDIGPADWDRILDVNLRGVLYLSQAFIPHMRENGGGSIICMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMAREFGPDGIRINCVTPGLIQTDITGGKLTDAMRADIIKGIPLSRLGDARDVAGAYLFLASDLASYITGAVI
DVNGGMLIHG
>Mature_250_residues
MLLKGKAVVISGAASPRGIGRSTATLMAEQGARIAILDLDEEQARDAAASLGPEHIGLACNVADLDSCKRAAAEVTEAFG
RVEVLCNIAGITQPVKTLDIGPADWDRILDVNLRGVLYLSQAFIPHMRENGGGSIICMSSVSAQRGGGIFGGPHYSAAKA
GVLGLAKAMAREFGPDGIRINCVTPGLIQTDITGGKLTDAMRADIIKGIPLSRLGDARDVAGAYLFLASDLASYITGAVI
DVNGGMLIHG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=231, Percent_Identity=35.9307359307359, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=36.046511627907, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI32483357, Length=238, Percent_Identity=32.3529411764706, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=30.6451612903226, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI126723750, Length=242, Percent_Identity=31.404958677686, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=30.1158301158301, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=32.258064516129, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=29.4354838709677, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI59889578, Length=221, Percent_Identity=33.0316742081448, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI4503301, Length=234, Percent_Identity=29.9145299145299, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=32.6530612244898, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=32.3076923076923, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=28.2352941176471, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4504505, Length=219, Percent_Identity=31.9634703196347, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI31542939, Length=207, Percent_Identity=29.4685990338164, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=174, Percent_Identity=28.735632183908, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=30.3664921465969, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40807363, Length=201, Percent_Identity=29.8507462686567, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI83715985, Length=260, Percent_Identity=31.1538461538462, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI224922801, Length=183, Percent_Identity=28.9617486338798, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI210032110, Length=203, Percent_Identity=24.6305418719212, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI302344755, Length=86, Percent_Identity=33.7209302325581, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI20149619, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=39.5161290322581, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=33.7349397590361, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=31.0483870967742, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=32.156862745098, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=31.7073170731707, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=30.8, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=33.75, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.9212598425197, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=33.203125, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=31.9672131147541, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=31.2741312741313, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=31.6872427983539, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=25.8964143426295, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788891, Length=240, Percent_Identity=25, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787545, Length=265, Percent_Identity=27.5471698113208, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=38.9558232931727, Blast_Score=170, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=35.0597609561753, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17560676, Length=238, Percent_Identity=29.8319327731092, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.3149606299213, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=31.0606060606061, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=30.8, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=29.718875502008, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=27.9527559055118, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=29.277566539924, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=28.5185185185185, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=28.957528957529, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=28.968253968254, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=239, Percent_Identity=29.2887029288703, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568967, Length=233, Percent_Identity=26.1802575107296, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=29.9242424242424, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=27.3076923076923, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=207, Percent_Identity=28.5024154589372, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=29.4776119402985, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=26.5873015873016, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=31.7829457364341, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=276, Percent_Identity=27.1739130434783, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=29.368029739777, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=26.7441860465116, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.8939393939394, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=202, Percent_Identity=27.2277227722772, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=25.9259259259259, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=27.9245283018868, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=26.9662921348315, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=26.2626262626263, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=25.8883248730964, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=26.2626262626263, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=26.5151515151515, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=27.9245283018868, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=30.0395256916996, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=34.136546184739, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.5301204819277, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=33.201581027668, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=32.046332046332, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=30.1587301587302, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=29.9595141700405, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=29.4573643410853, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18859837, Length=213, Percent_Identity=31.924882629108, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24644337, Length=233, Percent_Identity=31.3304721030043, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281364892, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649181, Length=207, Percent_Identity=26.0869565217391, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=30.8457711442786, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=30.8457711442786, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21358495, Length=209, Percent_Identity=29.1866028708134, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641232, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581726, Length=206, Percent_Identity=28.6407766990291, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640492, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25796; Mature: 25796

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKGKAVVISGAASPRGIGRSTATLMAEQGARIAILDLDEEQARDAAASLGPEHIGLAC
CCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCEEEE
NVADLDSCKRAAAEVTEAFGRVEVLCNIAGITQPVKTLDIGPADWDRILDVNLRGVLYLS
CHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCCCHHHEECCCCCCCCEEECCCCHHEEHH
QAFIPHMRENGGGSIICMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGPDGIRI
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
NCVTPGLIQTDITGGKLTDAMRADIIKGIPLSRLGDARDVAGAYLFLASDLASYITGAVI
EEECCCEEEECCCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEE
DVNGGMLIHG
EECCCEEEEC
>Mature Secondary Structure
MLLKGKAVVISGAASPRGIGRSTATLMAEQGARIAILDLDEEQARDAAASLGPEHIGLAC
CCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCEEEE
NVADLDSCKRAAAEVTEAFGRVEVLCNIAGITQPVKTLDIGPADWDRILDVNLRGVLYLS
CHHHHHHHHHHHHHHHHHHHHHHEEHHHHCCCCCHHHEECCCCCCCCEEECCCCHHEEHH
QAFIPHMRENGGGSIICMSSVSAQRGGGIFGGPHYSAAKAGVLGLAKAMAREFGPDGIRI
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
NCVTPGLIQTDITGGKLTDAMRADIIKGIPLSRLGDARDVAGAYLFLASDLASYITGAVI
EEECCCEEEECCCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCEEE
DVNGGMLIHG
EECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]