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The map label for this gene is intA [H]

Identifier: 13474795

GI number: 13474795

Start: 4643427

End: 4644614

Strand: Reverse

Name: intA [H]

Synonym: mll5763

Alternate gene names: 13474795

Gene position: 4644614-4643427 (Counterclockwise)

Preceding gene: 13474796

Following gene: 13474794

Centisome position: 66.01

GC content: 58.92

Gene sequence:

>1188_bases
ATGTCTCTCTCCGACTTCACGTGCAAGAACGCTAAGCCCAAGGACAAGCCGTATCGTCTTGCTGATGGCGACGGGCTTTA
TCTCCTCGTCCGGAACAACGGCTCCAAACTCTGGCAACTGCGGTACCGCTACCTGGAGAAGGAAAATATCCTCTCCTTTG
GAAAATACCCGCTGGTGTCACTTCTCGACGCGAGAGGAAAGCGCGACGACGCTAAGAGGCTGTTGATCGCCGGCATCAGC
CCCTCCACTAAACGCAAAGAGGAGAAGACCGCCGCCATCACGGAAGCACGCACCACCTTCGCCTTGGTCGCGGAGGAGTA
TGTCACGCGGATGGAGGAACGGGACGCTGCGGCGGCTACCATCAGCAAAACAAAATGGCTCCTGGAAGATCTGGCCGGCC
CACTCGCCAAGCGCCCCATTAACGAGATCACTCCAGCAGAAATTTTCCAACTCCTCCAGAAGATCGAAAAGAGTGGTCGA
AGAGAGACAGCGCGGCGTTTACGCAGCGTGATAGGCAGCGTCTTCCGCTTGGCCATTGTCACCTTACGGGCAGAGGCCGA
CCCAACCCTTCACCTCCGGGGCGCTCTCCAGCCGCCGAAAGTCAACGGTCGCGCCGCTATCACCGATGAAAATAAGTTCG
GCAAGCTCCTGATGACGGTTGACGAATACGACGGCTGGCCAACCATCAAGGCCGCCCTTCAGTTTCTTGCCCTCACCTGT
GTCCGTCCCGGCGAAGTACGGGGCGCCACGCGCGACGAGTTCGACCGAAAGAAGGCCGTCTGGCATATTCCGGCCGAGCG
CATGAAGATGCGTGCTCCGCACGACGTGCCACTGTCCAAACAGGCGCTTTCGGTCTTGGAAGAGGTCTGGCAGCTCTCAG
AGGACGGCGGCCTGGTCTTTCCTTCGATCCGCTCCACAAAACGGCCGCTTTCCGAGAACGCCATGAACGCTGCGCTACGA
CGTATGGGCTACGGAAAGGACGAAGTGACCGCACATGGTTTCCGGGTGACCGCCAGCACCATCCTCAACGCCCGCGACTA
CGATCCAGACGTCATTGAAGCTGTGCTGGCGCACCAGGACAAGAACGCCATCCGGCGGACCTACAACCGCGCGACCTATT
GGAACCAGCGGGTGACGCTAATGCAGGAGTGGGGAGATCTGTTAGACGCGTTAAAGGCGAACCATTAG

Upstream 100 bases:

>100_bases
CTAGTTTGGCGGTTCATGGTGACCTACCGCGTGCCGTTGCAACGCGTCGGTTTGTGGGTAACGATTTAGGCCTTACCCAC
AACCCGGGAGGTCCGTACCC

Downstream 100 bases:

>100_bases
TCTTACACACATTCCACGATCGGATCGCTGTTTTCCGTGTTGGAGTTGACGCTGCCGATATAGGTACTTGAGCCGTTAAC
CCGTGCGCCTCCAAGGCCGC

Product: symbiosis island integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSLSDFTCKNAKPKDKPYRLADGDGLYLLVRNNGSKLWQLRYRYLEKENILSFGKYPLVSLLDARGKRDDAKRLLIAGIS
PSTKRKEEKTAAITEARTTFALVAEEYVTRMEERDAAAATISKTKWLLEDLAGPLAKRPINEITPAEIFQLLQKIEKSGR
RETARRLRSVIGSVFRLAIVTLRAEADPTLHLRGALQPPKVNGRAAITDENKFGKLLMTVDEYDGWPTIKAALQFLALTC
VRPGEVRGATRDEFDRKKAVWHIPAERMKMRAPHDVPLSKQALSVLEEVWQLSEDGGLVFPSIRSTKRPLSENAMNAALR
RMGYGKDEVTAHGFRVTASTILNARDYDPDVIEAVLAHQDKNAIRRTYNRATYWNQRVTLMQEWGDLLDALKANH

Sequences:

>Translated_395_residues
MSLSDFTCKNAKPKDKPYRLADGDGLYLLVRNNGSKLWQLRYRYLEKENILSFGKYPLVSLLDARGKRDDAKRLLIAGIS
PSTKRKEEKTAAITEARTTFALVAEEYVTRMEERDAAAATISKTKWLLEDLAGPLAKRPINEITPAEIFQLLQKIEKSGR
RETARRLRSVIGSVFRLAIVTLRAEADPTLHLRGALQPPKVNGRAAITDENKFGKLLMTVDEYDGWPTIKAALQFLALTC
VRPGEVRGATRDEFDRKKAVWHIPAERMKMRAPHDVPLSKQALSVLEEVWQLSEDGGLVFPSIRSTKRPLSENAMNAALR
RMGYGKDEVTAHGFRVTASTILNARDYDPDVIEAVLAHQDKNAIRRTYNRATYWNQRVTLMQEWGDLLDALKANH
>Mature_394_residues
SLSDFTCKNAKPKDKPYRLADGDGLYLLVRNNGSKLWQLRYRYLEKENILSFGKYPLVSLLDARGKRDDAKRLLIAGISP
STKRKEEKTAAITEARTTFALVAEEYVTRMEERDAAAATISKTKWLLEDLAGPLAKRPINEITPAEIFQLLQKIEKSGRR
ETARRLRSVIGSVFRLAIVTLRAEADPTLHLRGALQPPKVNGRAAITDENKFGKLLMTVDEYDGWPTIKAALQFLALTCV
RPGEVRGATRDEFDRKKAVWHIPAERMKMRAPHDVPLSKQALSVLEEVWQLSEDGGLVFPSIRSTKRPLSENAMNAALRR
MGYGKDEVTAHGFRVTASTILNARDYDPDVIEAVLAHQDKNAIRRTYNRATYWNQRVTLMQEWGDLLDALKANH

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=392, Percent_Identity=38.7755102040816, Blast_Score=230, Evalue=9e-62,
Organism=Escherichia coli, GI145693166, Length=404, Percent_Identity=37.1287128712871, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1788690, Length=382, Percent_Identity=32.7225130890052, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44670; Mature: 44539

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSDFTCKNAKPKDKPYRLADGDGLYLLVRNNGSKLWQLRYRYLEKENILSFGKYPLVS
CCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHH
LLDARGKRDDAKRLLIAGISPSTKRKEEKTAAITEARTTFALVAEEYVTRMEERDAAAAT
HHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISKTKWLLEDLAGPLAKRPINEITPAEIFQLLQKIEKSGRRETARRLRSVIGSVFRLAIV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TLRAEADPTLHLRGALQPPKVNGRAAITDENKFGKLLMTVDEYDGWPTIKAALQFLALTC
HHCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
VRPGEVRGATRDEFDRKKAVWHIPAERMKMRAPHDVPLSKQALSVLEEVWQLSEDGGLVF
CCCCCCCCCCHHHHHHHHCEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEC
PSIRSTKRPLSENAMNAALRRMGYGKDEVTAHGFRVTASTILNARDYDPDVIEAVLAHQD
CCHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEEHHHHHCCCCCCHHHHHHHHHHCC
KNAIRRTYNRATYWNQRVTLMQEWGDLLDALKANH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLSDFTCKNAKPKDKPYRLADGDGLYLLVRNNGSKLWQLRYRYLEKENILSFGKYPLVS
CCCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHH
LLDARGKRDDAKRLLIAGISPSTKRKEEKTAAITEARTTFALVAEEYVTRMEERDAAAAT
HHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISKTKWLLEDLAGPLAKRPINEITPAEIFQLLQKIEKSGRRETARRLRSVIGSVFRLAIV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TLRAEADPTLHLRGALQPPKVNGRAAITDENKFGKLLMTVDEYDGWPTIKAALQFLALTC
HHCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
VRPGEVRGATRDEFDRKKAVWHIPAERMKMRAPHDVPLSKQALSVLEEVWQLSEDGGLVF
CCCCCCCCCCHHHHHHHHCEEECCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEC
PSIRSTKRPLSENAMNAALRRMGYGKDEVTAHGFRVTASTILNARDYDPDVIEAVLAHQD
CCHHHHCCCHHHHHHHHHHHHHCCCCCHHHHCCEEEEHHHHHCCCCCCHHHHHHHHHHCC
KNAIRRTYNRATYWNQRVTLMQEWGDLLDALKANH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]