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The map label for this gene is mmgC [H]

Identifier: 13474683

GI number: 13474683

Start: 4519012

End: 4520238

Strand: Direct

Name: mmgC [H]

Synonym: mlr5626

Alternate gene names: 13474683

Gene position: 4519012-4520238 (Clockwise)

Preceding gene: 13474682

Following gene: 13474684

Centisome position: 64.23

GC content: 61.86

Gene sequence:

>1227_bases
GTGAAATGCGCCCACCTCAATTCTGACGATGCGCTCTGGGAGGAGTACCATACCCACATGACCAACCCCGCCGAAATACT
TGGCCTTCCCAAGCCCGCCTGGGCCGCGGACGAGGTCGGCATGCTCTACGACATGGCAACCCGCTTCATGTCGGAGGAGA
TCGCGCCGCGCTACGACGAGTTCGAGAAGAACGAGATGGTCGACCGCGAAAGCTGGCGCAAGGCCGGTGCCGCCGGCCTG
CTCTGCGCCTCGATGCCGGAGGAATATGGCGGCTCCGGCGGCACCTTCGCGCATGAGAGCGCCATCATCGAGGCGATCGG
CCATGTCGGCGTCGACGGTTTCGGCATCGGCCTGCACAATTCGATCGTCGCGCCTTACATCCTTCACTACGGTTCGGAAG
AGCAGAAGAAGAAATGGCTGCCGAAGCTCGCCACCGGCGAGCTGATCGGCGCCATCGCCATGACCGAGCCGGGCGCCGGC
TCCGATCTGCAGGGCGTCAAGACGCGGGCCGAGAAGGACGGTAACCAGTACAGGATCAATGGTTCCAAGACCTTCATCAC
CAACGGCCAGCTGGCCAACTTCATCATCGTCGTCACCAAGACCGATCCGGAAAAGGGCGCCAAGGGCACCTCGCTGATCG
TCGTCGAGACCGACGAGGTCGAAGGTTTCGAGCGTGGCCGCAACCTCGACAAGATCGGCCTGAAGGCCAACGACACGTCG
GAACTGTTCTTCAACGACGTGCGTGTGCCGACCTCCAATCTGCTCGGCCACGAGGAAGGGCAGGGCTTTATCCAGCTGAT
GCAGCAGCTGCCGCAGGAGCGCTTGCAGATCGGCACCGGCGCCATCGCCATGATCGAGCGCGCGCTGGCGCTGACCATCG
AGTACGTCAAGGAGCGCAAGGCCTTCGGCAAGGCGATCATCGATTTCCAGAACACCCAGTTCAAGCTGGCCGAGCTCAAG
ACCGAGGCGACCATCGGCCGCGTCTTCTACAATGATTGCGTCACACGCCACATCAATGGCGGGCTCGATCCGGTGACGGC
CTCGATGGCCAAGTACTGGCTGAGCGACCTGCAGGGCAAAGTCGTCGACGAATGCCTTCAATTGCATGGCGGCTATGGCT
ACATGAATGAATACCCGATCGCCCGCATGTTCCGCGACGCTCGCGTCCAGCGCATCTACGGCGGCACCAACGAGATCATG
AAATTGCTGATCGGCCGCTCGCTCTGA

Upstream 100 bases:

>100_bases
CCCGTATTTCGAGTGGTGCGGACACGCTGATGGCCCTGCCCGCGGAAGCGTTCTAAAGATGGTTGCCCTCTCCCTCGAGG
GGAGGGTCGGTTGAGGCAGC

Downstream 100 bases:

>100_bases
AAGCGCCGTCGGCAAACCCAAGGAGCACGAAAATGGCCGAAGCTTATGTCTATGACGCCGTGCGCACGCCGCGCGGCAAG
GGCAAGAAGGACGGATCGCT

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKCAHLNSDDALWEEYHTHMTNPAEILGLPKPAWAADEVGMLYDMATRFMSEEIAPRYDEFEKNEMVDRESWRKAGAAGL
LCASMPEEYGGSGGTFAHESAIIEAIGHVGVDGFGIGLHNSIVAPYILHYGSEEQKKKWLPKLATGELIGAIAMTEPGAG
SDLQGVKTRAEKDGNQYRINGSKTFITNGQLANFIIVVTKTDPEKGAKGTSLIVVETDEVEGFERGRNLDKIGLKANDTS
ELFFNDVRVPTSNLLGHEEGQGFIQLMQQLPQERLQIGTGAIAMIERALALTIEYVKERKAFGKAIIDFQNTQFKLAELK
TEATIGRVFYNDCVTRHINGGLDPVTASMAKYWLSDLQGKVVDECLQLHGGYGYMNEYPIARMFRDARVQRIYGGTNEIM
KLLIGRSL

Sequences:

>Translated_408_residues
MKCAHLNSDDALWEEYHTHMTNPAEILGLPKPAWAADEVGMLYDMATRFMSEEIAPRYDEFEKNEMVDRESWRKAGAAGL
LCASMPEEYGGSGGTFAHESAIIEAIGHVGVDGFGIGLHNSIVAPYILHYGSEEQKKKWLPKLATGELIGAIAMTEPGAG
SDLQGVKTRAEKDGNQYRINGSKTFITNGQLANFIIVVTKTDPEKGAKGTSLIVVETDEVEGFERGRNLDKIGLKANDTS
ELFFNDVRVPTSNLLGHEEGQGFIQLMQQLPQERLQIGTGAIAMIERALALTIEYVKERKAFGKAIIDFQNTQFKLAELK
TEATIGRVFYNDCVTRHINGGLDPVTASMAKYWLSDLQGKVVDECLQLHGGYGYMNEYPIARMFRDARVQRIYGGTNEIM
KLLIGRSL
>Mature_408_residues
MKCAHLNSDDALWEEYHTHMTNPAEILGLPKPAWAADEVGMLYDMATRFMSEEIAPRYDEFEKNEMVDRESWRKAGAAGL
LCASMPEEYGGSGGTFAHESAIIEAIGHVGVDGFGIGLHNSIVAPYILHYGSEEQKKKWLPKLATGELIGAIAMTEPGAG
SDLQGVKTRAEKDGNQYRINGSKTFITNGQLANFIIVVTKTDPEKGAKGTSLIVVETDEVEGFERGRNLDKIGLKANDTS
ELFFNDVRVPTSNLLGHEEGQGFIQLMQQLPQERLQIGTGAIAMIERALALTIEYVKERKAFGKAIIDFQNTQFKLAELK
TEATIGRVFYNDCVTRHINGGLDPVTASMAKYWLSDLQGKVVDECLQLHGGYGYMNEYPIARMFRDARVQRIYGGTNEIM
KLLIGRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=363, Percent_Identity=51.5151515151515, Blast_Score=360, Evalue=1e-99,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=35.4497354497354, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=36.1516034985423, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4501859, Length=366, Percent_Identity=33.6065573770492, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI4557231, Length=366, Percent_Identity=34.6994535519126, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI187960098, Length=366, Percent_Identity=34.6994535519126, Blast_Score=208, Evalue=8e-54,
Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=32.7868852459016, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI7656849, Length=367, Percent_Identity=33.7874659400545, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI21361497, Length=393, Percent_Identity=33.587786259542, Blast_Score=198, Evalue=9e-51,
Organism=Homo sapiens, GI4557235, Length=426, Percent_Identity=32.3943661971831, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI76496475, Length=406, Percent_Identity=33.2512315270936, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI4503943, Length=387, Percent_Identity=28.4237726098191, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI7669494, Length=361, Percent_Identity=28.5318559556787, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI38505218, Length=290, Percent_Identity=30.6896551724138, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI48976061, Length=415, Percent_Identity=25.5421686746988, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI211971008, Length=415, Percent_Identity=25.5421686746988, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI87081958, Length=348, Percent_Identity=29.8850574712644, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1786223, Length=330, Percent_Identity=28.1818181818182, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI87081702, Length=421, Percent_Identity=23.7529691211401, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=375, Percent_Identity=36.5333333333333, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17569725, Length=372, Percent_Identity=34.6774193548387, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17533517, Length=367, Percent_Identity=36.2397820163488, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=35.149863760218, Blast_Score=217, Evalue=8e-57,
Organism=Caenorhabditis elegans, GI17551932, Length=364, Percent_Identity=35.7142857142857, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17508101, Length=387, Percent_Identity=33.3333333333333, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17570075, Length=366, Percent_Identity=34.6994535519126, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17505929, Length=365, Percent_Identity=35.0684931506849, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=32.3684210526316, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=38.2142857142857, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71985184, Length=393, Percent_Identity=31.5521628498728, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71982178, Length=269, Percent_Identity=32.3420074349442, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=36.4035087719298, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=350, Percent_Identity=30.5714285714286, Blast_Score=141, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=381, Percent_Identity=29.6587926509186, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI17531909, Length=235, Percent_Identity=29.7872340425532, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17562446, Length=348, Percent_Identity=28.448275862069, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355753, Length=374, Percent_Identity=36.3636363636364, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24666513, Length=384, Percent_Identity=31.7708333333333, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24660351, Length=372, Percent_Identity=34.6774193548387, Blast_Score=204, Evalue=9e-53,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=32.0754716981132, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=32.7956989247312, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281363737, Length=380, Percent_Identity=33.9473684210526, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19920834, Length=368, Percent_Identity=29.0760869565217, Blast_Score=131, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 45136; Mature: 45136

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCAHLNSDDALWEEYHTHMTNPAEILGLPKPAWAADEVGMLYDMATRFMSEEIAPRYDE
CCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
FEKNEMVDRESWRKAGAAGLLCASMPEEYGGSGGTFAHESAIIEAIGHVGVDGFGIGLHN
HHHHHCCCHHHHHHCCCCHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCEECCHHH
SIVAPYILHYGSEEQKKKWLPKLATGELIGAIAMTEPGAGSDLQGVKTRAEKDGNQYRIN
HHHHHHHHHCCCHHHHHHHCCCHHCCHHHEEEEECCCCCCCCCHHHHHHHHCCCCEEEEC
GSKTFITNGQLANFIIVVTKTDPEKGAKGTSLIVVETDEVEGFERGRNLDKIGLKANDTS
CCEEEEECCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCH
ELFFNDVRVPTSNLLGHEEGQGFIQLMQQLPQERLQIGTGAIAMIERALALTIEYVKERK
HHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AFGKAIIDFQNTQFKLAELKTEATIGRVFYNDCVTRHINGGLDPVTASMAKYWLSDLQGK
HHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHH
VVDECLQLHGGYGYMNEYPIARMFRDARVQRIYGGTNEIMKLLIGRSL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKCAHLNSDDALWEEYHTHMTNPAEILGLPKPAWAADEVGMLYDMATRFMSEEIAPRYDE
CCCCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
FEKNEMVDRESWRKAGAAGLLCASMPEEYGGSGGTFAHESAIIEAIGHVGVDGFGIGLHN
HHHHHCCCHHHHHHCCCCHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHCCCCCEECCHHH
SIVAPYILHYGSEEQKKKWLPKLATGELIGAIAMTEPGAGSDLQGVKTRAEKDGNQYRIN
HHHHHHHHHCCCHHHHHHHCCCHHCCHHHEEEEECCCCCCCCCHHHHHHHHCCCCEEEEC
GSKTFITNGQLANFIIVVTKTDPEKGAKGTSLIVVETDEVEGFERGRNLDKIGLKANDTS
CCEEEEECCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCH
ELFFNDVRVPTSNLLGHEEGQGFIQLMQQLPQERLQIGTGAIAMIERALALTIEYVKERK
HHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AFGKAIIDFQNTQFKLAELKTEATIGRVFYNDCVTRHINGGLDPVTASMAKYWLSDLQGK
HHHHHHEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHH
VVDECLQLHGGYGYMNEYPIARMFRDARVQRIYGGTNEIMKLLIGRSL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]