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The map label for this gene is yieH [H]

Identifier: 13474110

GI number: 13474110

Start: 3904741

End: 3905424

Strand: Reverse

Name: yieH [H]

Synonym: mll4919

Alternate gene names: 13474110

Gene position: 3905424-3904741 (Counterclockwise)

Preceding gene: 13474111

Following gene: 13474109

Centisome position: 55.51

GC content: 65.2

Gene sequence:

>684_bases
ATGACGCCTGAACTGGTCATCTTCGACTGCGATGGCGTGCTGGTCGACAGCGAGGCGCTCTCCGTCTCGGCGCTGCTCGG
CATGATCGAACGTGCCGGCGGCACTGTCAGCGAGGACGCCGCCTACGAGCATTTCCTCGGCAAGAGCATGAAGAGCGTGC
GCGAGATCCTTGGCCGCGACTTCGGCCTGGAGATCAGCGACCAGCATCTGACCGCCATGCGCGTCGACCTCATGCGCAAA
TTCCGTGAGGAGCTCAAGCCGATCCCCGGCGTCAAGGAAATGTTGCCGAAGCTCGGCCTGCCGTTCTGCGTCGCCTCTTC
GGGCACGCTGGAGCGCATCCGCTACGCGCTCGATGTCACCGGCCTGCTCGGGCTGATGGAACCGCATCTGTTCAGTGCCG
CCATGGTCGCCAAGGGAAAGCCGGCGCCCGACCTCTTCCTGCACGCCGCCGCCAGCATGCGGGCGCATCCGCGCAAATGC
CTCGTCATCGAGGACAGTCCGGCCGGGGTCGCGGCGGCGCGCGCGGCGGGCATGCGCGTCCTTGCCTTCACCGGCGGCGC
GCATGCCGGCAACCCTGCCTTGAAAGCGCGGCTTGCGTCGAGTGAACCGGACTTTATATTCGCTGACATGCTGCAATTGC
CCGATCTGATTGCAGGCCTGGGAGCGAGAGTTAGAGCATCTTGA

Upstream 100 bases:

>100_bases
CGAGGCCTTCGGCCACGCGCTCAACGTGCTGTGGGCCAATGGCGCCCGCGCCACGTTGACACGCTACATCGCCGGCAAGC
TCTGAAAGCTATCAGCCATC

Downstream 100 bases:

>100_bases
CGAAACAGTTTGTTTGCGCGGTCGATGTCGGCACCGGGAGCGCTCGCGCTGGCATTCTCGACGCCAGTGGCACCTTGCTT
GGCCGTGCCGATCGGCCGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTPELVIFDCDGVLVDSEALSVSALLGMIERAGGTVSEDAAYEHFLGKSMKSVREILGRDFGLEISDQHLTAMRVDLMRK
FREELKPIPGVKEMLPKLGLPFCVASSGTLERIRYALDVTGLLGLMEPHLFSAAMVAKGKPAPDLFLHAAASMRAHPRKC
LVIEDSPAGVAAARAAGMRVLAFTGGAHAGNPALKARLASSEPDFIFADMLQLPDLIAGLGARVRAS

Sequences:

>Translated_227_residues
MTPELVIFDCDGVLVDSEALSVSALLGMIERAGGTVSEDAAYEHFLGKSMKSVREILGRDFGLEISDQHLTAMRVDLMRK
FREELKPIPGVKEMLPKLGLPFCVASSGTLERIRYALDVTGLLGLMEPHLFSAAMVAKGKPAPDLFLHAAASMRAHPRKC
LVIEDSPAGVAAARAAGMRVLAFTGGAHAGNPALKARLASSEPDFIFADMLQLPDLIAGLGARVRAS
>Mature_226_residues
TPELVIFDCDGVLVDSEALSVSALLGMIERAGGTVSEDAAYEHFLGKSMKSVREILGRDFGLEISDQHLTAMRVDLMRKF
REELKPIPGVKEMLPKLGLPFCVASSGTLERIRYALDVTGLLGLMEPHLFSAAMVAKGKPAPDLFLHAAASMRAHPRKCL
VIEDSPAGVAAARAAGMRVLAFTGGAHAGNPALKARLASSEPDFIFADMLQLPDLIAGLGARVRAS

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=226, Percent_Identity=28.7610619469027, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082080, Length=212, Percent_Identity=29.7169811320755, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788021, Length=209, Percent_Identity=29.1866028708134, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20129151, Length=185, Percent_Identity=28.1081081081081, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17137324, Length=187, Percent_Identity=31.5508021390374, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24182; Mature: 24050

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPELVIFDCDGVLVDSEALSVSALLGMIERAGGTVSEDAAYEHFLGKSMKSVREILGRD
CCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
FGLEISDQHLTAMRVDLMRKFREELKPIPGVKEMLPKLGLPFCVASSGTLERIRYALDVT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHH
GLLGLMEPHLFSAAMVAKGKPAPDLFLHAAASMRAHPRKCLVIEDSPAGVAAARAAGMRV
HHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCEEE
LAFTGGAHAGNPALKARLASSEPDFIFADMLQLPDLIAGLGARVRAS
EEEECCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPELVIFDCDGVLVDSEALSVSALLGMIERAGGTVSEDAAYEHFLGKSMKSVREILGRD
CCCEEEEECCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
FGLEISDQHLTAMRVDLMRKFREELKPIPGVKEMLPKLGLPFCVASSGTLERIRYALDVT
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCCHHHHHHHHHHHH
GLLGLMEPHLFSAAMVAKGKPAPDLFLHAAASMRAHPRKCLVIEDSPAGVAAARAAGMRV
HHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCEEE
LAFTGGAHAGNPALKARLASSEPDFIFADMLQLPDLIAGLGARVRAS
EEEECCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]