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The map label for this gene is araB1 [H]

Identifier: 13474109

GI number: 13474109

Start: 3903158

End: 3904744

Strand: Reverse

Name: araB1 [H]

Synonym: mll4918

Alternate gene names: 13474109

Gene position: 3904744-3903158 (Counterclockwise)

Preceding gene: 13474110

Following gene: 13474102

Centisome position: 55.5

GC content: 66.67

Gene sequence:

>1587_bases
TTGACGAAACAGTTTGTTTGCGCGGTCGATGTCGGCACCGGGAGCGCTCGCGCTGGCATTCTCGACGCCAGTGGCACCTT
GCTTGGCCGTGCCGATCGGCCGATCGCCATGAACCAGCCGAAGCCCGATCATGCCGAGCATGATTCGCGCGATATCTGGT
CGGCGGTCTGCGCCGCCGTGCGTGCCGCCCGCGAAAAAGCCGGCGTCGCGGCGCAGGATATTGTTGGCATCTCGTTTGAT
GCGACCTGCTCGCTGGTGGTGCGCGACCGGCAAGGCGATCAGCTCAGCGTTTCGACCACGGGCGACAAGCGCTGGGACAC
CATCGTCTGGCTCGACCACCGCGCCATTTCCGAAGCAGACGAATGCACGGCGAGCAGCCACGAGGTGCTCAACTATATAG
GCGGCGTCATGTCGCCGGAAATGGCGACGCCGAAGCTGATGTGGCTGAAGCGCAACCTGCCGCAGACCTGGAATGAAGCC
GGCTATCTATTCGACCTGGCCGATTTCCTGACCTGGCAGGCGAGCGGCTCGCTGGCCCGCTCGCAATGCACACTGACGGC
GAAGTGGACTTATCTCGCACATGAGGAGAGCGCGTGGCAGCGCGATTTCTTCGAGATCGTCGGCCTCGACGATCTCTTTG
AGCACGGCAATCTGCCGGAGCGGGCTAGTCCGGTCGGCGCCGACATCGGCCCTCTGACGGCGCAAGCGGCGGCGGAACTT
GGTTTGACGGAAAGCTGCCGGGTCGGCGCCGGGGTCATCGATGCCTATGCCGGCGCGCTTGGCGTGCTTGGCGGCTTTGC
CGGTGATGAGCAGGATATTGGCCGGCATCTGGCGTTGATTGCCGGCACGTCGAGCTGCGTCATGGCGATGTCGCCCGACC
CGCAGCCTTTCGCCGGCGTCTGGGGCCCTTACTATGGCGCGGCGTTGCCAAAGCTGTGGCTGTCGGAAGGCGGCCAGTCG
GCTACCGGCGCGCTGCTCGACCACATCATCCGCTGGCACGGCGCCGGCGGCGAGCCGGATGCCGCCATGCATGCCAAAAT
CGCCAGGCGGGTCGCCGAACTGCGCGCCGCCGAGGGCGACAACCTCGCCGCGCGCCTGCATGTGCTGCCGGATTTTCACG
GTAACCGGTCGCCGCTCGCCGACCCGCATGCTGTCGGCGTCGTCAGCGGGCTGACGCTGGATTCCTCCTTCGACAGCCTG
TGCAAGCTCTACTGGCGCACCGCCGTCGGCATCGCGCTCGGCGTGCGCCATGTGCTGGAAGCGCTGAACGAGAACGGCTA
CCTGATCGACACGCTGCATGTCACCGGCGGCCACACCAAGAACCCACTGCTGATGGAGCTCTACGCCGACGCCACCGGCT
GCACGGTGGTCGAACCGCTGGCCGACGAGGCGGTGCTGCTCGGCACCGGCATGGTCGCCGCCACCGCCGCCGGGCTTTTC
CCCGACCTCAATGCCGCCTGCCTTGCCATGCAGCAGGGCGGCAAGAGGCGTGCCGCCAACCCGGCCGCCGGCGCCCGCTT
CGACCGCGACTACCGGATTTTCCTGGAAATGCACCGCCAGCGCCAGGCGCTTGACGACATCCGGTAG

Upstream 100 bases:

>100_bases
TGAAAGCGCGGCTTGCGTCGAGTGAACCGGACTTTATATTCGCTGACATGCTGCAATTGCCCGATCTGATTGCAGGCCTG
GGAGCGAGAGTTAGAGCATC

Downstream 100 bases:

>100_bases
GCCTTGCTTACTGCTTGCGCAGCGACGCGCCTGACGTCGCGTCGAACAAATGGATGCTTTCTTCCTCGAATGCGTAACGG
ACAGGAGCATTCAGCGCCGG

Product: ribitol kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MTKQFVCAVDVGTGSARAGILDASGTLLGRADRPIAMNQPKPDHAEHDSRDIWSAVCAAVRAAREKAGVAAQDIVGISFD
ATCSLVVRDRQGDQLSVSTTGDKRWDTIVWLDHRAISEADECTASSHEVLNYIGGVMSPEMATPKLMWLKRNLPQTWNEA
GYLFDLADFLTWQASGSLARSQCTLTAKWTYLAHEESAWQRDFFEIVGLDDLFEHGNLPERASPVGADIGPLTAQAAAEL
GLTESCRVGAGVIDAYAGALGVLGGFAGDEQDIGRHLALIAGTSSCVMAMSPDPQPFAGVWGPYYGAALPKLWLSEGGQS
ATGALLDHIIRWHGAGGEPDAAMHAKIARRVAELRAAEGDNLAARLHVLPDFHGNRSPLADPHAVGVVSGLTLDSSFDSL
CKLYWRTAVGIALGVRHVLEALNENGYLIDTLHVTGGHTKNPLLMELYADATGCTVVEPLADEAVLLGTGMVAATAAGLF
PDLNAACLAMQQGGKRRAANPAAGARFDRDYRIFLEMHRQRQALDDIR

Sequences:

>Translated_528_residues
MTKQFVCAVDVGTGSARAGILDASGTLLGRADRPIAMNQPKPDHAEHDSRDIWSAVCAAVRAAREKAGVAAQDIVGISFD
ATCSLVVRDRQGDQLSVSTTGDKRWDTIVWLDHRAISEADECTASSHEVLNYIGGVMSPEMATPKLMWLKRNLPQTWNEA
GYLFDLADFLTWQASGSLARSQCTLTAKWTYLAHEESAWQRDFFEIVGLDDLFEHGNLPERASPVGADIGPLTAQAAAEL
GLTESCRVGAGVIDAYAGALGVLGGFAGDEQDIGRHLALIAGTSSCVMAMSPDPQPFAGVWGPYYGAALPKLWLSEGGQS
ATGALLDHIIRWHGAGGEPDAAMHAKIARRVAELRAAEGDNLAARLHVLPDFHGNRSPLADPHAVGVVSGLTLDSSFDSL
CKLYWRTAVGIALGVRHVLEALNENGYLIDTLHVTGGHTKNPLLMELYADATGCTVVEPLADEAVLLGTGMVAATAAGLF
PDLNAACLAMQQGGKRRAANPAAGARFDRDYRIFLEMHRQRQALDDIR
>Mature_527_residues
TKQFVCAVDVGTGSARAGILDASGTLLGRADRPIAMNQPKPDHAEHDSRDIWSAVCAAVRAAREKAGVAAQDIVGISFDA
TCSLVVRDRQGDQLSVSTTGDKRWDTIVWLDHRAISEADECTASSHEVLNYIGGVMSPEMATPKLMWLKRNLPQTWNEAG
YLFDLADFLTWQASGSLARSQCTLTAKWTYLAHEESAWQRDFFEIVGLDDLFEHGNLPERASPVGADIGPLTAQAAAELG
LTESCRVGAGVIDAYAGALGVLGGFAGDEQDIGRHLALIAGTSSCVMAMSPDPQPFAGVWGPYYGAALPKLWLSEGGQSA
TGALLDHIIRWHGAGGEPDAAMHAKIARRVAELRAAEGDNLAARLHVLPDFHGNRSPLADPHAVGVVSGLTLDSSFDSLC
KLYWRTAVGIALGVRHVLEALNENGYLIDTLHVTGGHTKNPLLMELYADATGCTVVEPLADEAVLLGTGMVAATAAGLFP
DLNAACLAMQQGGKRRAANPAAGARFDRDYRIFLEMHRQRQALDDIR

Specific function: Key Enzyme In The Regulation Of Glycerol Uptake And Metabolism. [C]

COG id: COG1069

COG function: function code C; Ribulose kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulokinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=541, Percent_Identity=42.5138632162662, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI164663830, Length=565, Percent_Identity=40.7079646017699, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI42794763, Length=477, Percent_Identity=24.9475890985325, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4504007, Length=476, Percent_Identity=25.6302521008403, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI189409120, Length=476, Percent_Identity=25.6302521008403, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786249, Length=515, Percent_Identity=25.4368932038835, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790005, Length=529, Percent_Identity=22.8733459357278, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=24.0556660039761, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320314, Length=520, Percent_Identity=37.8846153846154, Blast_Score=322, Evalue=7e-89,
Organism=Saccharomyces cerevisiae, GI6324080, Length=481, Percent_Identity=25.3638253638254, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24657106, Length=536, Percent_Identity=39.1791044776119, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24657102, Length=536, Percent_Identity=39.1791044776119, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI21356323, Length=430, Percent_Identity=38.6046511627907, Blast_Score=266, Evalue=2e-71,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018484
- InterPro:   IPR005929 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.16 [H]

Molecular weight: Translated: 56369; Mature: 56238

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQFVCAVDVGTGSARAGILDASGTLLGRADRPIAMNQPKPDHAEHDSRDIWSAVCAAV
CCCEEEEEEECCCCCCCCCEEECCCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHH
RAAREKAGVAAQDIVGISFDATCSLVVRDRQGDQLSVSTTGDKRWDTIVWLDHRAISEAD
HHHHHHCCCCHHHEEEEEECCEEEEEEEECCCCEEEEEECCCCCCCEEEEECCHHHCCHH
ECTASSHEVLNYIGGVMSPEMATPKLMWLKRNLPQTWNEAGYLFDLADFLTWQASGSLAR
HHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEHHHHHHCCCCCCCCC
SQCTLTAKWTYLAHEESAWQRDFFEIVGLDDLFEHGNLPERASPVGADIGPLTAQAAAEL
CEEEEEEEEEEEECCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHC
GLTESCRVGAGVIDAYAGALGVLGGFAGDEQDIGRHLALIAGTSSCVMAMSPDPQPFAGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCEEEEECCCCCCCCCC
WGPYYGAALPKLWLSEGGQSATGALLDHIIRWHGAGGEPDAAMHAKIARRVAELRAAEGD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
NLAARLHVLPDFHGNRSPLADPHAVGVVSGLTLDSSFDSLCKLYWRTAVGIALGVRHVLE
CEEEEEEECCCCCCCCCCCCCCCHHHEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALNENGYLIDTLHVTGGHTKNPLLMELYADATGCTVVEPLADEAVLLGTGMVAATAAGLF
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCEEECCCCCCEEEEECCHHHHHHHHCC
PDLNAACLAMQQGGKRRAANPAAGARFDRDYRIFLEMHRQRQALDDIR
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKQFVCAVDVGTGSARAGILDASGTLLGRADRPIAMNQPKPDHAEHDSRDIWSAVCAAV
CCEEEEEEECCCCCCCCCEEECCCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHH
RAAREKAGVAAQDIVGISFDATCSLVVRDRQGDQLSVSTTGDKRWDTIVWLDHRAISEAD
HHHHHHCCCCHHHEEEEEECCEEEEEEEECCCCEEEEEECCCCCCCEEEEECCHHHCCHH
ECTASSHEVLNYIGGVMSPEMATPKLMWLKRNLPQTWNEAGYLFDLADFLTWQASGSLAR
HHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEHHHHHHCCCCCCCCC
SQCTLTAKWTYLAHEESAWQRDFFEIVGLDDLFEHGNLPERASPVGADIGPLTAQAAAEL
CEEEEEEEEEEEECCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHC
GLTESCRVGAGVIDAYAGALGVLGGFAGDEQDIGRHLALIAGTSSCVMAMSPDPQPFAGV
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCEEEEECCCCCCCCCC
WGPYYGAALPKLWLSEGGQSATGALLDHIIRWHGAGGEPDAAMHAKIARRVAELRAAEGD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCC
NLAARLHVLPDFHGNRSPLADPHAVGVVSGLTLDSSFDSLCKLYWRTAVGIALGVRHVLE
CEEEEEEECCCCCCCCCCCCCCCHHHEEECCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ALNENGYLIDTLHVTGGHTKNPLLMELYADATGCTVVEPLADEAVLLGTGMVAATAAGLF
HHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCCEEECCCCCCEEEEECCHHHHHHHHCC
PDLNAACLAMQQGGKRRAANPAAGARFDRDYRIFLEMHRQRQALDDIR
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA