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The map label for this gene is 13474059

Identifier: 13474059

GI number: 13474059

Start: 3853290

End: 3854348

Strand: Reverse

Name: 13474059

Synonym: mll4847

Alternate gene names: NA

Gene position: 3854348-3853290 (Counterclockwise)

Preceding gene: 13474062

Following gene: 13474055

Centisome position: 54.78

GC content: 69.22

Gene sequence:

>1059_bases
ATGGCAGACGGGGAAAAACGGATCGTCATCGCCGGTGCCGGCAGCATCGGCTGTTATGTCGGCGGTTGCCTGGCACTCGC
CGGGCGGCAGGTTGTCCTGCTGGCGCGGCCACGCATCGAGGCGGCGCTGCGGCAGGACGGATTGCGCGTCAGCGACCTTG
ACGGCCGCGATCGCCTGGTCAAGCCCGACGCACTCGGGATCACCGCCGATCCCGCCGTCGCGCTGCCTGAGGCGGATGTG
ATCCTGGTGACCGTCAAGAGCGGCGCCACGCAGGAGATGGCAGCGCTGATCGAGGCCCATGCCCGCCCCGATGCGGTGGT
GGTCAGCCTGCAGAACGGCGTCGACAATGCCGACAGACTGCGCGCCGGGTCTGGCCAGCGAACCGTGCTGGCCGGCATGG
TGCCGTTCAATGTGGTGCAATCGCCTGACGGCGAGCTGCCGCTGCCCGTCCACCGCGCCAGCGAGGGCAAGGTTATGATC
GAGGACGGCGGCGCCGGACTTGCCGGTCTTCTTGATGTCGCCCGTCTTCTTGATGTCGAGGGGCTGGCGGTCGAGACACA
TGGCGACATGAAAGCCGTGCTGTGGGGCAAGCTTTTGATGAACCTCAACAACGCGCTGGTGGCGCTGTCGGACCTGCCGC
TGGCGCGCGAACTCGCCGATCGCCGCTGGCGGCTGATCCTGGCCGGCCAGATCGACGAGGCGCTGCGGGCGATGAAAGCC
TCCGGCATCGTGCCAGCGCGGATCGCCGGACTGCGGCCGGCGCTGCTGCCGAAAGTGCTGCGGCTGCCGGACTGGCTGTT
CAAACTGCTGGCGCGGCGCATGCTGGCGATCGACCCCGAGGCGCGCTCGTCGATGTGGGACGATCTGCAGCGCGGCCGGC
CGACGGAGATCGGCGAACTGCAAGGCGCGGTGCTCGGCCTCGCCCAGAGAACGGGGACGCCGGCGCCGCTCTTGAAAAAC
GTTAACGCTTTGGTGCGCGCGGCGGAAGCGGCGCGGCTTGGCGCGCCCGGGCTGGCGCCGGAACAGGTTGCTCCGCCGGG
TGCCTCTCGATCAGCGTGA

Upstream 100 bases:

>100_bases
GGGCCTGTCACGGGCAGACATGGGGGCCAGCCCAATGGCAGACGATGCCGCCGACATTATGGTTTTCATGTCGTATAGTC
GGGCCGGTGCGGAGTAAGAC

Downstream 100 bases:

>100_bases
TCTTCTGCCAGATCTTGCGCGACAGGTTCGAGCTCAAATTCTCGATATCATTGACGCCGTCGATGACGACGTCATCATTG
ACCGACTGGGCGAAGAGCGC

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MADGEKRIVIAGAGSIGCYVGGCLALAGRQVVLLARPRIEAALRQDGLRVSDLDGRDRLVKPDALGITADPAVALPEADV
ILVTVKSGATQEMAALIEAHARPDAVVVSLQNGVDNADRLRAGSGQRTVLAGMVPFNVVQSPDGELPLPVHRASEGKVMI
EDGGAGLAGLLDVARLLDVEGLAVETHGDMKAVLWGKLLMNLNNALVALSDLPLARELADRRWRLILAGQIDEALRAMKA
SGIVPARIAGLRPALLPKVLRLPDWLFKLLARRMLAIDPEARSSMWDDLQRGRPTEIGELQGAVLGLAQRTGTPAPLLKN
VNALVRAAEAARLGAPGLAPEQVAPPGASRSA

Sequences:

>Translated_352_residues
MADGEKRIVIAGAGSIGCYVGGCLALAGRQVVLLARPRIEAALRQDGLRVSDLDGRDRLVKPDALGITADPAVALPEADV
ILVTVKSGATQEMAALIEAHARPDAVVVSLQNGVDNADRLRAGSGQRTVLAGMVPFNVVQSPDGELPLPVHRASEGKVMI
EDGGAGLAGLLDVARLLDVEGLAVETHGDMKAVLWGKLLMNLNNALVALSDLPLARELADRRWRLILAGQIDEALRAMKA
SGIVPARIAGLRPALLPKVLRLPDWLFKLLARRMLAIDPEARSSMWDDLQRGRPTEIGELQGAVLGLAQRTGTPAPLLKN
VNALVRAAEAARLGAPGLAPEQVAPPGASRSA
>Mature_351_residues
ADGEKRIVIAGAGSIGCYVGGCLALAGRQVVLLARPRIEAALRQDGLRVSDLDGRDRLVKPDALGITADPAVALPEADVI
LVTVKSGATQEMAALIEAHARPDAVVVSLQNGVDNADRLRAGSGQRTVLAGMVPFNVVQSPDGELPLPVHRASEGKVMIE
DGGAGLAGLLDVARLLDVEGLAVETHGDMKAVLWGKLLMNLNNALVALSDLPLARELADRRWRLILAGQIDEALRAMKAS
GIVPARIAGLRPALLPKVLRLPDWLFKLLARRMLAIDPEARSSMWDDLQRGRPTEIGELQGAVLGLAQRTGTPAPLLKNV
NALVRAAEAARLGAPGLAPEQVAPPGASRSA

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 36946; Mature: 36814

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADGEKRIVIAGAGSIGCYVGGCLALAGRQVVLLARPRIEAALRQDGLRVSDLDGRDRLV
CCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEECCCCCCCEE
KPDALGITADPAVALPEADVILVTVKSGATQEMAALIEAHARPDAVVVSLQNGVDNADRL
CCCCCCCCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
RAGSGQRTVLAGMVPFNVVQSPDGELPLPVHRASEGKVMIEDGGAGLAGLLDVARLLDVE
CCCCCCCEEEEECCCHHHCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHCCC
GLAVETHGDMKAVLWGKLLMNLNNALVALSDLPLARELADRRWRLILAGQIDEALRAMKA
CEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCEEEEEECCHHHHHHHHHH
SGIVPARIAGLRPALLPKVLRLPDWLFKLLARRMLAIDPEARSSMWDDLQRGRPTEIGEL
CCCCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHH
QGAVLGLAQRTGTPAPLLKNVNALVRAAEAARLGAPGLAPEQVAPPGASRSA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADGEKRIVIAGAGSIGCYVGGCLALAGRQVVLLARPRIEAALRQDGLRVSDLDGRDRLV
CCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEECCCCCCCEE
KPDALGITADPAVALPEADVILVTVKSGATQEMAALIEAHARPDAVVVSLQNGVDNADRL
CCCCCCCCCCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
RAGSGQRTVLAGMVPFNVVQSPDGELPLPVHRASEGKVMIEDGGAGLAGLLDVARLLDVE
CCCCCCCEEEEECCCHHHCCCCCCCCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHCCC
GLAVETHGDMKAVLWGKLLMNLNNALVALSDLPLARELADRRWRLILAGQIDEALRAMKA
CEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCEEEEEECCHHHHHHHHHH
SGIVPARIAGLRPALLPKVLRLPDWLFKLLARRMLAIDPEARSSMWDDLQRGRPTEIGEL
CCCCHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHH
QGAVLGLAQRTGTPAPLLKNVNALVRAAEAARLGAPGLAPEQVAPPGASRSA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]