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The map label for this gene is argB [H]

Identifier: 13474041

GI number: 13474041

Start: 3838421

End: 3839314

Strand: Direct

Name: argB [H]

Synonym: mlr4826

Alternate gene names: 13474041

Gene position: 3838421-3839314 (Clockwise)

Preceding gene: 13474040

Following gene: 13474045

Centisome position: 54.55

GC content: 64.09

Gene sequence:

>894_bases
ATGACGGATATCGCCGCCACCGCCGAAATGCAGGCCGCCCTGCTGTCGCGCGCTTTGCCCTACATGCAGCGTTACGAACA
CAAGACCGTCGTGGTGAAATATGGCGGCCACGCCATGGGCGACATCGAGCTCGGCAAGGCTTTTGCGCGCGACATCGCGC
TGCTGAAGCAATCCGGCGTCAACCCGATCGTCGTTCATGGCGGCGGGCCGCAGATCGGCGCCATGCTGACCAAGATGGGC
ATCGAATCCAAGTTCGAGGGTGGGCTGCGCGTCACCGACCAGAAGACGGTCGAGATCGTCGAGATGGTGCTGGCCGGCTC
GATCAACAAGGAGATCGTCGCGCTCATCAACGCCGAAGGCGAATGGGCGATTGGCCTCTGCGGCAAAGACGGCAACATGG
TGTTCGCCGAAAAGGCGCGCAAGACCATGATCGACCCCGATTCCAACATCGAGCGTGTGCTCGATCTCGGCTTCGTCGGC
GAACCGGTCGAGGTCGACCGCACGCTGCTCGACCTCCTGGCCCGCTCCGAAATGATCCCGGTGCTGGCGCCGGTGGCGCC
CGGCCGCGACGGCCACACCTACAACATCAATGCCGACACTTTCGCCGGTGCCATCGCCGGCGCCTGCAAGGCCTCGCGCC
TTTTGTTCCTGACCGACGTGCCCGGCGTACTCGACAAGAACAAGAAGCTGATCGACGAATTGACCGTCGCCGAGGCCAAG
GCGCTGATCAAGGACGGCACGGTCTCGGGCGGCATGATCCCCAAGGTCGAAACCTGCATCGAGGCGATCGAGCGCGGCGT
CGAGGGCGTCGTCATCCTCAACGGCAAGACGCCGCATGCGGTGCTGCTCGAGCTCTTCACCGAACACGGCGCCGGCACGC
TGATCGTGCCCTGA

Upstream 100 bases:

>100_bases
GCTAAGACGCCGCCGTCTTAATCTGATGCATGTCGCCCAAAAGTGCCCGGCGGTTTTGGGGCAACGACATGCACAAACCA
AAAAGCCAGGGAACCGCCCG

Downstream 100 bases:

>100_bases
GGCGACTCATGCGTCGCCCGCAGCCAACCGATCAGGCAGGCTGCGGAAGGCGCGCGATGACCTTTATCTCGAAGTCGAAG
CCCGCCAGCCAGTTCACGCC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTDIAATAEMQAALLSRALPYMQRYEHKTVVVKYGGHAMGDIELGKAFARDIALLKQSGVNPIVVHGGGPQIGAMLTKMG
IESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTMIDPDSNIERVLDLGFVG
EPVEVDRTLLDLLARSEMIPVLAPVAPGRDGHTYNINADTFAGAIAGACKASRLLFLTDVPGVLDKNKKLIDELTVAEAK
ALIKDGTVSGGMIPKVETCIEAIERGVEGVVILNGKTPHAVLLELFTEHGAGTLIVP

Sequences:

>Translated_297_residues
MTDIAATAEMQAALLSRALPYMQRYEHKTVVVKYGGHAMGDIELGKAFARDIALLKQSGVNPIVVHGGGPQIGAMLTKMG
IESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTMIDPDSNIERVLDLGFVG
EPVEVDRTLLDLLARSEMIPVLAPVAPGRDGHTYNINADTFAGAIAGACKASRLLFLTDVPGVLDKNKKLIDELTVAEAK
ALIKDGTVSGGMIPKVETCIEAIERGVEGVVILNGKTPHAVLLELFTEHGAGTLIVP
>Mature_296_residues
TDIAATAEMQAALLSRALPYMQRYEHKTVVVKYGGHAMGDIELGKAFARDIALLKQSGVNPIVVHGGGPQIGAMLTKMGI
ESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEGEWAIGLCGKDGNMVFAEKARKTMIDPDSNIERVLDLGFVGE
PVEVDRTLLDLLARSEMIPVLAPVAPGRDGHTYNINADTFAGAIAGACKASRLLFLTDVPGVLDKNKKLIDELTVAEAKA
LIKDGTVSGGMIPKVETCIEAIERGVEGVVILNGKTPHAVLLELFTEHGAGTLIVP

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=302, Percent_Identity=26.4900662251656, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693208, Length=234, Percent_Identity=30.3418803418803, Blast_Score=84, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=279, Percent_Identity=26.5232974910394, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31549; Mature: 31418

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIAATAEMQAALLSRALPYMQRYEHKTVVVKYGGHAMGDIELGKAFARDIALLKQSGV
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHCCC
NPIVVHGGGPQIGAMLTKMGIESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEG
CEEEEECCCCHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCEEEEEEECCC
EWAIGLCGKDGNMVFAEKARKTMIDPDSNIERVLDLGFVGEPVEVDRTLLDLLARSEMIP
CEEEEEECCCCCEEEHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VLAPVAPGRDGHTYNINADTFAGAIAGACKASRLLFLTDVPGVLDKNKKLIDELTVAEAK
EEECCCCCCCCCEEEECCHHHHHHHHHHHHHCEEEEEECCCCHHCCCHHHHHHHHHHHHH
ALIKDGTVSGGMIPKVETCIEAIERGVEGVVILNGKTPHAVLLELFTEHGAGTLIVP
HHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEECC
>Mature Secondary Structure 
TDIAATAEMQAALLSRALPYMQRYEHKTVVVKYGGHAMGDIELGKAFARDIALLKQSGV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCHHHHHHHHHHHHHHHHCCC
NPIVVHGGGPQIGAMLTKMGIESKFEGGLRVTDQKTVEIVEMVLAGSINKEIVALINAEG
CEEEEECCCCHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCEEEEEEECCC
EWAIGLCGKDGNMVFAEKARKTMIDPDSNIERVLDLGFVGEPVEVDRTLLDLLARSEMIP
CEEEEEECCCCCEEEHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
VLAPVAPGRDGHTYNINADTFAGAIAGACKASRLLFLTDVPGVLDKNKKLIDELTVAEAK
EEECCCCCCCCCEEEECCHHHHHHHHHHHHHCEEEEEECCCCHHCCCHHHHHHHHHHHHH
ALIKDGTVSGGMIPKVETCIEAIERGVEGVVILNGKTPHAVLLELFTEHGAGTLIVP
HHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA