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The map label for this gene is rhtB [H]

Identifier: 13473876

GI number: 13473876

Start: 3663941

End: 3664558

Strand: Reverse

Name: rhtB [H]

Synonym: mll4618

Alternate gene names: 13473876

Gene position: 3664558-3663941 (Counterclockwise)

Preceding gene: 13473877

Following gene: 13473875

Centisome position: 52.08

GC content: 67.31

Gene sequence:

>618_bases
ATGACCCTCACCGGCTTCCTCGCCTACAGTGCCGCACTCGGCATCGCCGCCGCCATTCCTGGCCCCGGCGTCACAGCGCT
TGTCGCGCGGGCGCTCGGCTCCGGCTTCCGCTCGTCGCTGGCCATGTCCTTTGGCCTGATGCTGGGCGACCTCACCTACC
TGACCGCCGTGGTGCTCGGCCTCGCCTTCGTCGCGCAGACCTTCGGCATGGTGTTCCTCGCCATCAAATGGGCCGGCGTC
GCCTATCTGGCGTTTCTGGGCTGGCGTTTCTGGACCGCCGGCATCACGCCCGAGACGGTCGAAGCCAGGAAGGGCAAGGG
CGGACTGGTGTCGAGCTTTGTCGCCGGCCTCACCGTCACGCTCGGCAATCCGAAGACGATGATCTTCTACCTGGCGATCA
CCCCGACCATCGTCGACCTGAAGACGATCACGCTGGCCGATTACGGCATTCTCGCCGCGCTGACGGTGGTCGTGCTGTTC
GTCGTACTGGTTCCCTACCTGGCGCTCGCCGCCAAGGCGCGCTGGTTCCTGAAATCGCCGCGCGCGCTGAAGCTGCTGAA
CCGCACCGCCGCCGGCTTCATGGTGGGCGCCGCGGCAGCGATCGCGGCCCGTCAGTAG

Upstream 100 bases:

>100_bases
CGGATGGCGCGGTATCTGGTGCAATAGAATCCGGCTGCCAGGGAATTCAACCCTGGCCCGTTCCATGCGAAAAGGATCGC
CTGATCCAGGACCACTCGCC

Downstream 100 bases:

>100_bases
CACGCTTTCAGCCAAAACATTCCGGGGCCAGGCTTTCCCGTGAAATGCTTTTCCGGGACAAGGGCGTTTTAGACACAGGC
CCCACTCGGATATTTCCGGC

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTLTGFLAYSAALGIAAAIPGPGVTALVARALGSGFRSSLAMSFGLMLGDLTYLTAVVLGLAFVAQTFGMVFLAIKWAGV
AYLAFLGWRFWTAGITPETVEARKGKGGLVSSFVAGLTVTLGNPKTMIFYLAITPTIVDLKTITLADYGILAALTVVVLF
VVLVPYLALAAKARWFLKSPRALKLLNRTAAGFMVGAAAAIAARQ

Sequences:

>Translated_205_residues
MTLTGFLAYSAALGIAAAIPGPGVTALVARALGSGFRSSLAMSFGLMLGDLTYLTAVVLGLAFVAQTFGMVFLAIKWAGV
AYLAFLGWRFWTAGITPETVEARKGKGGLVSSFVAGLTVTLGNPKTMIFYLAITPTIVDLKTITLADYGILAALTVVVLF
VVLVPYLALAAKARWFLKSPRALKLLNRTAAGFMVGAAAAIAARQ
>Mature_204_residues
TLTGFLAYSAALGIAAAIPGPGVTALVARALGSGFRSSLAMSFGLMLGDLTYLTAVVLGLAFVAQTFGMVFLAIKWAGVA
YLAFLGWRFWTAGITPETVEARKGKGGLVSSFVAGLTVTLGNPKTMIFYLAITPTIVDLKTITLADYGILAALTVVVLFV
VLVPYLALAAKARWFLKSPRALKLLNRTAAGFMVGAAAAIAARQ

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=208, Percent_Identity=29.8076923076923, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21353; Mature: 21222

Theoretical pI: Translated: 10.93; Mature: 10.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTGFLAYSAALGIAAAIPGPGVTALVARALGSGFRSSLAMSFGLMLGDLTYLTAVVLG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFVAQTFGMVFLAIKWAGVAYLAFLGWRFWTAGITPETVEARKGKGGLVSSFVAGLTVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHEEEE
LGNPKTMIFYLAITPTIVDLKTITLADYGILAALTVVVLFVVLVPYLALAAKARWFLKSP
ECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RALKLLNRTAAGFMVGAAAAIAARQ
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLTGFLAYSAALGIAAAIPGPGVTALVARALGSGFRSSLAMSFGLMLGDLTYLTAVVLG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAFVAQTFGMVFLAIKWAGVAYLAFLGWRFWTAGITPETVEARKGKGGLVSSFVAGLTVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHEEEE
LGNPKTMIFYLAITPTIVDLKTITLADYGILAALTVVVLFVVLVPYLALAAKARWFLKSP
ECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RALKLLNRTAAGFMVGAAAAIAARQ
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]