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The map label for this gene is 13473877

Identifier: 13473877

GI number: 13473877

Start: 3664670

End: 3666049

Strand: Reverse

Name: 13473877

Synonym: mll4619

Alternate gene names: NA

Gene position: 3666049-3664670 (Counterclockwise)

Preceding gene: 13473878

Following gene: 13473876

Centisome position: 52.1

GC content: 65.0

Gene sequence:

>1380_bases
ATGGAGGACAAGATGATCCGATTGGCCGGGCTGGTGATCCCCGCCCTCTTTCTCACAACAGCGGGGTTCGCCCAGCAGGC
GGACCAGCCGGTGCTGAAGGGCGCTGCCGCCTTCGGCGACTGGCGAGCCGACAGGCCTGGCGTGCTTCGCCTGATCAAGC
CGGAAGACCTGCCAAAGCCCTATGTCACCAAGTCGGTGTCGAACAGTGCCGGGCTTGCCGACATGCCGGCGGGCGCGAAG
CCGCAATTGCCGCCGGGCTTTTCGGCCGAGCTGATCGCATCCGGCATCGACAATCCGCGTGTCGTGCGTGTCGCACCCAA
TGGCGACCTGTTCGTCGCCGACAGCGAAGCCAACCAGGTCCGCGTCTATCGCCTGGCCAAGGACAGCGCCAAGCCCGCCG
AGGACGGCATCTTCGCCGGCAATCTCAACCAGCCCTATGGCATTGCCTTCTATCCGCCGGGCGATGATCCGCAATGGGTC
TATGTCGCCAACAGCGACAGCATCGTGCGCTTCGCCTACCGCAGTGGCGACCTGAAGGCATCGGGCGAACCCGAAATCAT
CGTCGCCAATATTCCGTCGAACCATCACTGGACCCGCGACATTGTTTTCTCGCCGGATGGCAAGACGCTCTATCTGTCGG
TCGGCTCCGGTTCGAACGTCGCCGAAGACATGGGCAAGGCGCCGGAAGGCGGCCTCGACGTGTGGGTGAAATCGAAGCCG
CTGGGCGCGACCTGGGGCTCCGAAGAGGGGCGCGCCGACGTGCAGGCCTTCGATCCGGACGGCAAGAACGGCCGCATCGT
TGCCACCGGCCTGCGCAACTGCTCGGGCATGACCATCCAGCCGGCGACCGGCGCGCTGTGGTGCGTCGTCAACGAGCGCG
ACGCGCTGGGCGACAATGTGCCGTTCGAATACGCCACCTCAGTCAAGGACGGCGCGTACTATGGCTGGCCCTGGTACTAT
ATCGGCAATCACGAGGACCCGCGCCATAAGGGCGCGCGCCCCGATCTCGCCGGCAAGGCAACCATTCCCGACGTGCTGAT
GCAGGCGCATTCGGCGCCGCTCAACATCGCATTCTACGACCGCAAGGATTTGCCCGCCGACAGCGGTTTTCCCAAGGAAT
ACCGGGGCGATGCCTTCGTCGCCCTGCACGGTTCGTGGAATCGCGGCAACAGGACCGGCTACAAAATCGTCCGCCTGCTG
TTCAAGGACGGCAAGCCGACCGGCGAGTATGAGGACTTCATGACCGGCTTCGTCGTCTCCAACGGCGAGGTCTGGGGCCG
GCCGGTGGGCGTGGCGGTGGCCCATGACGGCGCGCTGATCATGACCGAGGATGGCAACGGCTCGATCTGGCGCGTGACCT
ATGATGGCGGCCGGTCCTGA

Upstream 100 bases:

>100_bases
GATTTTTACGCTGCCGGGACATAAACAGGCAAATCGCCTCCCTCAACTCGTCGTGTGAGGCGGAACCCCGGGGGCAAATC
GGCCGTTCCTTCGCGACCAA

Downstream 100 bases:

>100_bases
GGGATCTTACTCGGATGGCGCGGTATCTGGTGCAATAGAATCCGGCTGCCAGGGAATTCAACCCTGGCCCGTTCCATGCG
AAAAGGATCGCCTGATCCAG

Product: L-sorbosone dehydrogenase

Products: NA

Alternate protein names: SNDH [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MEDKMIRLAGLVIPALFLTTAGFAQQADQPVLKGAAAFGDWRADRPGVLRLIKPEDLPKPYVTKSVSNSAGLADMPAGAK
PQLPPGFSAELIASGIDNPRVVRVAPNGDLFVADSEANQVRVYRLAKDSAKPAEDGIFAGNLNQPYGIAFYPPGDDPQWV
YVANSDSIVRFAYRSGDLKASGEPEIIVANIPSNHHWTRDIVFSPDGKTLYLSVGSGSNVAEDMGKAPEGGLDVWVKSKP
LGATWGSEEGRADVQAFDPDGKNGRIVATGLRNCSGMTIQPATGALWCVVNERDALGDNVPFEYATSVKDGAYYGWPWYY
IGNHEDPRHKGARPDLAGKATIPDVLMQAHSAPLNIAFYDRKDLPADSGFPKEYRGDAFVALHGSWNRGNRTGYKIVRLL
FKDGKPTGEYEDFMTGFVVSNGEVWGRPVGVAVAHDGALIMTEDGNGSIWRVTYDGGRS

Sequences:

>Translated_459_residues
MEDKMIRLAGLVIPALFLTTAGFAQQADQPVLKGAAAFGDWRADRPGVLRLIKPEDLPKPYVTKSVSNSAGLADMPAGAK
PQLPPGFSAELIASGIDNPRVVRVAPNGDLFVADSEANQVRVYRLAKDSAKPAEDGIFAGNLNQPYGIAFYPPGDDPQWV
YVANSDSIVRFAYRSGDLKASGEPEIIVANIPSNHHWTRDIVFSPDGKTLYLSVGSGSNVAEDMGKAPEGGLDVWVKSKP
LGATWGSEEGRADVQAFDPDGKNGRIVATGLRNCSGMTIQPATGALWCVVNERDALGDNVPFEYATSVKDGAYYGWPWYY
IGNHEDPRHKGARPDLAGKATIPDVLMQAHSAPLNIAFYDRKDLPADSGFPKEYRGDAFVALHGSWNRGNRTGYKIVRLL
FKDGKPTGEYEDFMTGFVVSNGEVWGRPVGVAVAHDGALIMTEDGNGSIWRVTYDGGRS
>Mature_459_residues
MEDKMIRLAGLVIPALFLTTAGFAQQADQPVLKGAAAFGDWRADRPGVLRLIKPEDLPKPYVTKSVSNSAGLADMPAGAK
PQLPPGFSAELIASGIDNPRVVRVAPNGDLFVADSEANQVRVYRLAKDSAKPAEDGIFAGNLNQPYGIAFYPPGDDPQWV
YVANSDSIVRFAYRSGDLKASGEPEIIVANIPSNHHWTRDIVFSPDGKTLYLSVGSGSNVAEDMGKAPEGGLDVWVKSKP
LGATWGSEEGRADVQAFDPDGKNGRIVATGLRNCSGMTIQPATGALWCVVNERDALGDNVPFEYATSVKDGAYYGWPWYY
IGNHEDPRHKGARPDLAGKATIPDVLMQAHSAPLNIAFYDRKDLPADSGFPKEYRGDAFVALHGSWNRGNRTGYKIVRLL
FKDGKPTGEYEDFMTGFVVSNGEVWGRPVGVAVAHDGALIMTEDGNGSIWRVTYDGGRS

Specific function: Converts L-sorbosone into 2-keto-L-gulonic acid (2KGA) [H]

COG id: COG2133

COG function: function code G; Glucose/sorbosone dehydrogenases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.burgdorferi BB024 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR012938
- InterPro:   IPR011041 [H]

Pfam domain/function: PF07995 GSDH [H]

EC number: NA

Molecular weight: Translated: 49489; Mature: 49489

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKMIRLAGLVIPALFLTTAGFAQQADQPVLKGAAAFGDWRADRPGVLRLIKPEDLPKP
CCCHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCC
YVTKSVSNSAGLADMPAGAKPQLPPGFSAELIASGIDNPRVVRVAPNGDLFVADSEANQV
HHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCEEEEECCCCEE
RVYRLAKDSAKPAEDGIFAGNLNQPYGIAFYPPGDDPQWVYVANSDSIVRFAYRSGDLKA
EEEEEECCCCCCCCCCEEECCCCCCCEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCC
SGEPEIIVANIPSNHHWTRDIVFSPDGKTLYLSVGSGSNVAEDMGKAPEGGLDVWVKSKP
CCCCCEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHCCCCCCCEEEEEECCC
LGATWGSEEGRADVQAFDPDGKNGRIVATGLRNCSGMTIQPATGALWCVVNERDALGDNV
CCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEECCCCEEEEEEECCCCCCCCC
PFEYATSVKDGAYYGWPWYYIGNHEDPRHKGARPDLAGKATIPDVLMQAHSAPLNIAFYD
CCCEECCCCCCCEECCEEEEECCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
RKDLPADSGFPKEYRGDAFVALHGSWNRGNRTGYKIVRLLFKDGKPTGEYEDFMTGFVVS
CCCCCCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHEEEHHHCCCCCCCHHHHEEEEEEE
NGEVWGRPVGVAVAHDGALIMTEDGNGSIWRVTYDGGRS
CCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEECCCCC
>Mature Secondary Structure
MEDKMIRLAGLVIPALFLTTAGFAQQADQPVLKGAAAFGDWRADRPGVLRLIKPEDLPKP
CCCHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCC
YVTKSVSNSAGLADMPAGAKPQLPPGFSAELIASGIDNPRVVRVAPNGDLFVADSEANQV
HHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCEEEEECCCCEE
RVYRLAKDSAKPAEDGIFAGNLNQPYGIAFYPPGDDPQWVYVANSDSIVRFAYRSGDLKA
EEEEEECCCCCCCCCCEEECCCCCCCEEEEECCCCCCCEEEEECCCCEEEEEEECCCCCC
SGEPEIIVANIPSNHHWTRDIVFSPDGKTLYLSVGSGSNVAEDMGKAPEGGLDVWVKSKP
CCCCCEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHCCCCCCCEEEEEECCC
LGATWGSEEGRADVQAFDPDGKNGRIVATGLRNCSGMTIQPATGALWCVVNERDALGDNV
CCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCEEECCCCEEEEEEECCCCCCCCC
PFEYATSVKDGAYYGWPWYYIGNHEDPRHKGARPDLAGKATIPDVLMQAHSAPLNIAFYD
CCCEECCCCCCCEECCEEEEECCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEC
RKDLPADSGFPKEYRGDAFVALHGSWNRGNRTGYKIVRLLFKDGKPTGEYEDFMTGFVVS
CCCCCCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHEEEHHHCCCCCCCHHHHEEEEEEE
NGEVWGRPVGVAVAHDGALIMTEDGNGSIWRVTYDGGRS
CCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7574579 [H]