Click here to switch to the map view.

The map label for this gene is pyc [H]

Identifier: 13473387

GI number: 13473387

Start: 3171442

End: 3174900

Strand: Reverse

Name: pyc [H]

Synonym: mll3969

Alternate gene names: 13473387

Gene position: 3174900-3171442 (Counterclockwise)

Preceding gene: 13473388

Following gene: 13473386

Centisome position: 45.12

GC content: 64.73

Gene sequence:

>3459_bases
TTGGCCATCACGAAGATCCTCGTCGCCAACCGGTCAGAAATCGCCATCCGCGTCTTTCGCGCGGCCAATGAACTGGGCCT
CAAAACCGTGGCGATCTGGGCCGAGGAAGACAAATATTCGCTGCACCGCTTCAAGGCCGACGAGAGCTACCAGGTCGGGC
GCGGTCCGCATCTCACCAAGGATATGGGGCCGATCGAGAGCTATCTGTCGATCGAGGAGGTGATCCGCGTCGCCCGGCTC
TCGGGCGCCGATGCCATCCACCCCGGCTACGGGCTTCTGTCCGAAAGCCCCGAATTCGCCGAAGCCTGCGCGCAAGCGGG
CATCACCTTCATCGGGCCGAAGCCGGACACGATGCGCCGCCTCGGCAACAAGGTCGCGGCGCGCAATCTCGCCATCGAGG
TCGGCGTGCCTGTCATTCCCGCCACCGATCCGTTGCCGGACGATATGGAGGCGGTCAAGAAACTGGCCAAGGAGATCGGC
TATCCAGTGATGCTCAAGGCCTCCTGGGGCGGCGGTGGGCGCGGCATGCGCGCCATCCGCTCCGAGGCCGATCTCGCCCG
TGAGGTCACGGAAGGCAAGCGCGAGGCGAAAGCCGCCTTCGGCAAGGACGAGGTCTATCTCGAAAAGCTGATCGAGCGCG
CCCGCCACGTCGAGGTGCAGGTGCTTGGCGACACGCATGGCAATGCCGTGCACCTGTTCGAGCGCGACTGCTCGATCCAG
CGCCGCAACCAGAAGGTCGTCGAGCGGGCGCCGGCGCCCTATCTCGAAATGTCGCAGCGCGAGGAGCTTTGCGGCTACGC
GCTGAAGATCGCGCGCGAGACCAGCTATATCGGCGCCGGCACGGTCGAGTTCCTGCAGGATGCCGATACCGGAAAATTCT
ATTTCATCGAGGTCAACCCGCGCATCCAGGTCGAGCATACCGTCACCGAGCAGGTGACCGGCATCGATATCGTCAAGGCG
CAGATCCACATCCTCGACGGCTTCGCCATCGGCACACCGCAATCGGGCGTGCCGGCGCAGAAGGATATCAGGCTGAACGG
CCATGCCTTGCAGTGCCGCATCACCACCGAGGATCCCGAGCACAATTTCATCCCGGACTATGGCCGCATCACCGCCTATC
GCGGCGCCACCGGCTTCGGCATCCGGCTGGATGGCGGCACCGCCTATTCTGGCGCGGTCATCACCCGCTTCTACGATCCG
CTGCTGGAGAAGGTGACGGCGTGGGCGCCGACGCCGGCCGAGACCATTGCCCGCATGAACCGGGCGCTGCGCGAATTCCG
CATTCGCGGCGTTGCCACCAACCTCACCTTCCTCGAAGCGATCATCAACCACCCGAGCTTCGCCGACAATTCCTACACGA
CCAAGTTCATCGACACGACGCCGGAGCTGTTCCAGCAGGTCAAGCGGCAGGACCGCGCGACCAAGCTGCTCAACTATCTG
GCCGATGTCAGCGTCAACGGCCATCCCGAGACGCGCGGCCGGCCGACGCCGAAGGCCGATGCGGCCGCACCGGTCGTGCC
CTATCTCAACGGCAATGTGCCGGGCGGCAGCAAGCAGAAGCTGGACGTGCTCGGTCCGGAAAAATTCGCCGGCTGGATGC
GCGAACAAAGGCAAGTTCTGGTCACCGATACGACGATGCGCGACGGCCACCAGTCGCTGCTCGCGACGCGCATGCGCACG
CACGACATTGCCAATATTGCCGGCACCTATGCGCGCGCCCTGCCGCAGCTTCTGTCGCTCGAATGCTGGGGCGGCGCGAC
CTTCGACGTCGCCATGCGCTTCCTTACCGAGGATCCTTGGGAGCGGCTGTCGCTGGTGCGCGAGGCGGCGCCCAACCTGT
TGCTGCAGATGCTGCTGCGCGGCGCCAACGGCGTCGGTTACACCAATTATCCCGACAATGTCGTGCAGCATTTCGTCAAG
CAGGCGGCGAGCGGCGGTATCGACCTGTTCCGCGTCTTCGACTGCCTGAACTGGGTCGAGAACATGCGCGTCGCCATGGA
CGCGGTCGGCGCCGAAGGCAAGCTGATCGAAGCGGCGATGTGCTACACCGGCGACATTCTCGATCCGGCGCGGGCCAAAT
ACGATCTGAAATATTATGTCGGCCTGGCCAGCGAATTGCAGGCCGCCGGCGCCCACATCATCGCCGTCAAGGACATGGCC
GGCCTGTTGAAGCCCGCCGCCGCCCGCGTGCTGTTCAAGGCGCTGCGCGAGGCGACCGACCTGCCGATCCATTTCCATAC
CCACGACACGTCTGGCCTGTCGGCGGCGACCGTGCTGGCGGCGGTTGAGAGCGGCGTCGACGCCATCGATGCGGCGATGG
ACGCCTTCTCCGGCAACACGTCGCAGCCTTGCCTGGGCTCGATCGTCGAGGCGCTGAAGGGCACCGAGCGCGACCCGGGC
CTCGACCCGCAATGGATCCGCAAGATCTCGTTCTACTGGGAAGCGGTGCGCAACCAGTACGCCGCCTTCGAAAGCGACCT
CAAAGGGCCGGCTTCGGAAGTCTACCTGCATGAAATGCCGGGCGGACAATTCACCAACCTCAAGGAGCAGGCGCGCTCGC
TCGGGCTGGAAACGCGCTGGCATGAGGTGGCGCAGACCTATCACGACGTCAATCTGATGTTCGGCGACATCGTCAAGGTG
ACGCCGTCATCCAAGGTCGTCGGCGACATGGCCCTGATGATGGTCAGCCAGGACCTGACCGTCGCCGATGTCGAGAACCC
GGCCAGGGATATTGCCTTCCCGGACTCGGTCGTCTCGATGCTGCGCGGCGATCTCGGCCAGTCGCCCGGCGGTTGGCCGG
CGGCGCTGCAGAAGAAGGCGCTGAAAGGCGACGAGCCGATCACGGCACGGCCAGGCTCGCTGCTCAAGCCCGCCGATCTC
AAGGCCAGCCGCAAGGAGATCGAGGAGAAGCTCGAGCGCAAGCTCTCGGAATACGAATTCGCCTCCTGGCTGATGTATCC
GAAGGTGTTCACTGACTTCGCCGGCGCGCAGGAAACCTACGGCCCGGTCAGCGTCCTGCCGACGCCGACCTATTTCTACG
GCATGAAATCGGAAGACGAGATCTTCATCGACATCGAGAAGGGTAAGACGCTGGTCGTGCGGTGCCTTGCCATCGGCGAT
GTGGACGACAAGGGCATGGTCACGGTGTTCTTCGAGCTCAACGGCCAGCCACGGCGCGTGAAGGTGCCGGACCGGGCGCA
TGGCGCCTCCGCCGCCAAGGCGCGCCGTAAGGCCGAGCCTGGCAACGAGGCGCATGTCGGCGCGCCGATGCCGGGCGTGG
TTTCGGCGCTTTCGGTCGCCACGGGGCAAGCGGTGAAAGCCGGTGACGTGCTGCTGTCCATCGAGGCGATGAAGATGGAA
ACGGCGCTGCATGCCGAGCGTGACGGCACCGTCGCCGAGGTGCTGGTCAAGGCCGGCGACCAGATCGATGCCAAGGATCT
GCTGATAGCCTTCGCTTGA

Upstream 100 bases:

>100_bases
TAAATCGGTTTAAACCGGCGCTGATTTTGTTTGCACTGCAGCATTTTCACGCTAATCATTGCACCGATTTCCCGTTCCTT
CCGCTGCTGGAGCCCAGTCC

Downstream 100 bases:

>100_bases
GAGCCGGCAAAGAGAGGGCAGGCTGTCGGCAGCCCTCATGCCTTGTTCGATAACAGCTTGACCCGCCGCCGCCGGTCGGG
CATCGAACCGGCTCAAATTT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1152; Mature: 1151

Protein sequence:

>1152_residues
MAITKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKYSLHRFKADESYQVGRGPHLTKDMGPIESYLSIEEVIRVARL
SGADAIHPGYGLLSESPEFAEACAQAGITFIGPKPDTMRRLGNKVAARNLAIEVGVPVIPATDPLPDDMEAVKKLAKEIG
YPVMLKASWGGGGRGMRAIRSEADLAREVTEGKREAKAAFGKDEVYLEKLIERARHVEVQVLGDTHGNAVHLFERDCSIQ
RRNQKVVERAPAPYLEMSQREELCGYALKIARETSYIGAGTVEFLQDADTGKFYFIEVNPRIQVEHTVTEQVTGIDIVKA
QIHILDGFAIGTPQSGVPAQKDIRLNGHALQCRITTEDPEHNFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRFYDP
LLEKVTAWAPTPAETIARMNRALREFRIRGVATNLTFLEAIINHPSFADNSYTTKFIDTTPELFQQVKRQDRATKLLNYL
ADVSVNGHPETRGRPTPKADAAAPVVPYLNGNVPGGSKQKLDVLGPEKFAGWMREQRQVLVTDTTMRDGHQSLLATRMRT
HDIANIAGTYARALPQLLSLECWGGATFDVAMRFLTEDPWERLSLVREAAPNLLLQMLLRGANGVGYTNYPDNVVQHFVK
QAASGGIDLFRVFDCLNWVENMRVAMDAVGAEGKLIEAAMCYTGDILDPARAKYDLKYYVGLASELQAAGAHIIAVKDMA
GLLKPAAARVLFKALREATDLPIHFHTHDTSGLSAATVLAAVESGVDAIDAAMDAFSGNTSQPCLGSIVEALKGTERDPG
LDPQWIRKISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHEVAQTYHDVNLMFGDIVKV
TPSSKVVGDMALMMVSQDLTVADVENPARDIAFPDSVVSMLRGDLGQSPGGWPAALQKKALKGDEPITARPGSLLKPADL
KASRKEIEEKLERKLSEYEFASWLMYPKVFTDFAGAQETYGPVSVLPTPTYFYGMKSEDEIFIDIEKGKTLVVRCLAIGD
VDDKGMVTVFFELNGQPRRVKVPDRAHGASAAKARRKAEPGNEAHVGAPMPGVVSALSVATGQAVKAGDVLLSIEAMKME
TALHAERDGTVAEVLVKAGDQIDAKDLLIAFA

Sequences:

>Translated_1152_residues
MAITKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKYSLHRFKADESYQVGRGPHLTKDMGPIESYLSIEEVIRVARL
SGADAIHPGYGLLSESPEFAEACAQAGITFIGPKPDTMRRLGNKVAARNLAIEVGVPVIPATDPLPDDMEAVKKLAKEIG
YPVMLKASWGGGGRGMRAIRSEADLAREVTEGKREAKAAFGKDEVYLEKLIERARHVEVQVLGDTHGNAVHLFERDCSIQ
RRNQKVVERAPAPYLEMSQREELCGYALKIARETSYIGAGTVEFLQDADTGKFYFIEVNPRIQVEHTVTEQVTGIDIVKA
QIHILDGFAIGTPQSGVPAQKDIRLNGHALQCRITTEDPEHNFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRFYDP
LLEKVTAWAPTPAETIARMNRALREFRIRGVATNLTFLEAIINHPSFADNSYTTKFIDTTPELFQQVKRQDRATKLLNYL
ADVSVNGHPETRGRPTPKADAAAPVVPYLNGNVPGGSKQKLDVLGPEKFAGWMREQRQVLVTDTTMRDGHQSLLATRMRT
HDIANIAGTYARALPQLLSLECWGGATFDVAMRFLTEDPWERLSLVREAAPNLLLQMLLRGANGVGYTNYPDNVVQHFVK
QAASGGIDLFRVFDCLNWVENMRVAMDAVGAEGKLIEAAMCYTGDILDPARAKYDLKYYVGLASELQAAGAHIIAVKDMA
GLLKPAAARVLFKALREATDLPIHFHTHDTSGLSAATVLAAVESGVDAIDAAMDAFSGNTSQPCLGSIVEALKGTERDPG
LDPQWIRKISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHEVAQTYHDVNLMFGDIVKV
TPSSKVVGDMALMMVSQDLTVADVENPARDIAFPDSVVSMLRGDLGQSPGGWPAALQKKALKGDEPITARPGSLLKPADL
KASRKEIEEKLERKLSEYEFASWLMYPKVFTDFAGAQETYGPVSVLPTPTYFYGMKSEDEIFIDIEKGKTLVVRCLAIGD
VDDKGMVTVFFELNGQPRRVKVPDRAHGASAAKARRKAEPGNEAHVGAPMPGVVSALSVATGQAVKAGDVLLSIEAMKME
TALHAERDGTVAEVLVKAGDQIDAKDLLIAFA
>Mature_1151_residues
AITKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKYSLHRFKADESYQVGRGPHLTKDMGPIESYLSIEEVIRVARLS
GADAIHPGYGLLSESPEFAEACAQAGITFIGPKPDTMRRLGNKVAARNLAIEVGVPVIPATDPLPDDMEAVKKLAKEIGY
PVMLKASWGGGGRGMRAIRSEADLAREVTEGKREAKAAFGKDEVYLEKLIERARHVEVQVLGDTHGNAVHLFERDCSIQR
RNQKVVERAPAPYLEMSQREELCGYALKIARETSYIGAGTVEFLQDADTGKFYFIEVNPRIQVEHTVTEQVTGIDIVKAQ
IHILDGFAIGTPQSGVPAQKDIRLNGHALQCRITTEDPEHNFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRFYDPL
LEKVTAWAPTPAETIARMNRALREFRIRGVATNLTFLEAIINHPSFADNSYTTKFIDTTPELFQQVKRQDRATKLLNYLA
DVSVNGHPETRGRPTPKADAAAPVVPYLNGNVPGGSKQKLDVLGPEKFAGWMREQRQVLVTDTTMRDGHQSLLATRMRTH
DIANIAGTYARALPQLLSLECWGGATFDVAMRFLTEDPWERLSLVREAAPNLLLQMLLRGANGVGYTNYPDNVVQHFVKQ
AASGGIDLFRVFDCLNWVENMRVAMDAVGAEGKLIEAAMCYTGDILDPARAKYDLKYYVGLASELQAAGAHIIAVKDMAG
LLKPAAARVLFKALREATDLPIHFHTHDTSGLSAATVLAAVESGVDAIDAAMDAFSGNTSQPCLGSIVEALKGTERDPGL
DPQWIRKISFYWEAVRNQYAAFESDLKGPASEVYLHEMPGGQFTNLKEQARSLGLETRWHEVAQTYHDVNLMFGDIVKVT
PSSKVVGDMALMMVSQDLTVADVENPARDIAFPDSVVSMLRGDLGQSPGGWPAALQKKALKGDEPITARPGSLLKPADLK
ASRKEIEEKLERKLSEYEFASWLMYPKVFTDFAGAQETYGPVSVLPTPTYFYGMKSEDEIFIDIEKGKTLVVRCLAIGDV
DDKGMVTVFFELNGQPRRVKVPDRAHGASAAKARRKAEPGNEAHVGAPMPGVVSALSVATGQAVKAGDVLLSIEAMKMET
ALHAERDGTVAEVLVKAGDQIDAKDLLIAFA

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1154, Percent_Identity=47.7469670710572, Blast_Score=1045, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1154, Percent_Identity=47.7469670710572, Blast_Score=1045, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1154, Percent_Identity=47.7469670710572, Blast_Score=1045, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=456, Percent_Identity=43.859649122807, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI65506442, Length=464, Percent_Identity=41.5948275862069, Blast_Score=345, Evalue=1e-94,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=41.5948275862069, Blast_Score=345, Evalue=2e-94,
Organism=Homo sapiens, GI295821183, Length=464, Percent_Identity=41.5948275862069, Blast_Score=345, Evalue=2e-94,
Organism=Homo sapiens, GI134142062, Length=517, Percent_Identity=30.5609284332689, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI38679960, Length=565, Percent_Identity=29.5575221238938, Blast_Score=226, Evalue=8e-59,
Organism=Homo sapiens, GI38679974, Length=565, Percent_Identity=29.5575221238938, Blast_Score=226, Evalue=8e-59,
Organism=Homo sapiens, GI38679977, Length=565, Percent_Identity=29.5575221238938, Blast_Score=226, Evalue=9e-59,
Organism=Homo sapiens, GI38679967, Length=565, Percent_Identity=29.5575221238938, Blast_Score=226, Evalue=9e-59,
Organism=Homo sapiens, GI38679971, Length=565, Percent_Identity=29.5575221238938, Blast_Score=226, Evalue=1e-58,
Organism=Escherichia coli, GI1789654, Length=457, Percent_Identity=44.8577680525164, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1786216, Length=272, Percent_Identity=25.7352941176471, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1153, Percent_Identity=49.3495229835212, Blast_Score=1082, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=466, Percent_Identity=44.206008583691, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567343, Length=464, Percent_Identity=40.301724137931, Blast_Score=322, Evalue=7e-88,
Organism=Caenorhabditis elegans, GI133931226, Length=504, Percent_Identity=28.3730158730159, Blast_Score=198, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71997168, Length=466, Percent_Identity=29.1845493562232, Blast_Score=193, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=466, Percent_Identity=29.1845493562232, Blast_Score=193, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1164, Percent_Identity=46.9072164948454, Blast_Score=1046, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1159, Percent_Identity=47.5409836065574, Blast_Score=1043, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=454, Percent_Identity=39.4273127753304, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6324343, Length=523, Percent_Identity=30.019120458891, Blast_Score=222, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6323863, Length=435, Percent_Identity=31.7241379310345, Blast_Score=211, Evalue=6e-55,
Organism=Drosophila melanogaster, GI24652212, Length=1154, Percent_Identity=48.1802426343154, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1154, Percent_Identity=48.1802426343154, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1154, Percent_Identity=48.1802426343154, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1154, Percent_Identity=48.1802426343154, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1154, Percent_Identity=48.1802426343154, Blast_Score=1051, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1170, Percent_Identity=47.4358974358974, Blast_Score=1045, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1170, Percent_Identity=47.4358974358974, Blast_Score=1045, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1170, Percent_Identity=47.4358974358974, Blast_Score=1045, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1170, Percent_Identity=47.4358974358974, Blast_Score=1045, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1170, Percent_Identity=47.4358974358974, Blast_Score=1045, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=457, Percent_Identity=40.0437636761488, Blast_Score=343, Evalue=4e-94,
Organism=Drosophila melanogaster, GI24651759, Length=419, Percent_Identity=38.9021479713604, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI161076409, Length=512, Percent_Identity=29.8828125, Blast_Score=213, Evalue=7e-55,
Organism=Drosophila melanogaster, GI161076407, Length=512, Percent_Identity=29.8828125, Blast_Score=213, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24586460, Length=512, Percent_Identity=29.8828125, Blast_Score=213, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24586458, Length=512, Percent_Identity=29.8828125, Blast_Score=213, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126016; Mature: 125885

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAITKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKYSLHRFKADESYQVGRGPHLTK
CCCEEEEEECCCHHEEHHHHHHHHCCCEEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCC
DMGPIESYLSIEEVIRVARLSGADAIHPGYGLLSESPEFAEACAQAGITFIGPKPDTMRR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCHHHHH
LGNKVAARNLAIEVGVPVIPATDPLPDDMEAVKKLAKEIGYPVMLKASWGGGGRGMRAIR
HHHHHHHCCEEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
SEADLAREVTEGKREAKAAFGKDEVYLEKLIERARHVEVQVLGDTHGNAVHLFERDCSIQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEEEECCCCCEEEEEECCCCHH
RRNQKVVERAPAPYLEMSQREELCGYALKIARETSYIGAGTVEFLQDADTGKFYFIEVNP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEECC
RIQVEHTVTEQVTGIDIVKAQIHILDGFAIGTPQSGVPAQKDIRLNGHALQCRITTEDPE
EEEEEEEHHHHHCCCEEEEEEEEEEECEEECCCCCCCCCCCCEEECCEEEEEEEECCCCC
HNFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRFYDPLLEKVTAWAPTPAETIARMN
CCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RALREFRIRGVATNLTFLEAIINHPSFADNSYTTKFIDTTPELFQQVKRQDRATKLLNYL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ADVSVNGHPETRGRPTPKADAAAPVVPYLNGNVPGGSKQKLDVLGPEKFAGWMREQRQVL
HHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEECCCHHHHHHHHHHCCEEE
VTDTTMRDGHQSLLATRMRTHDIANIAGTYARALPQLLSLECWGGATFDVAMRFLTEDPW
EEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHH
ERLSLVREAAPNLLLQMLLRGANGVGYTNYPDNVVQHFVKQAASGGIDLFRVFDCLNWVE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NMRVAMDAVGAEGKLIEAAMCYTGDILDPARAKYDLKYYVGLASELQAAGAHIIAVKDMA
HHHHHHHHCCCCCCEEEEHHHHCCCCCCCHHHCEEEHEEECHHHHHHHCCCEEEEEHHHH
GLLKPAAARVLFKALREATDLPIHFHTHDTSGLSAATVLAAVESGVDAIDAAMDAFSGNT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCC
SQPCLGSIVEALKGTERDPGLDPQWIRKISFYWEAVRNQYAAFESDLKGPASEVYLHEMP
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECC
GGQFTNLKEQARSLGLETRWHEVAQTYHDVNLMFGDIVKVTPSSKVVGDMALMMVSQDLT
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHEEECCEEEECCCCHHHHHHHHHHHHCCCE
VADVENPARDIAFPDSVVSMLRGDLGQSPGGWPAALQKKALKGDEPITARPGSLLKPADL
EEECCCCHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
KASRKEIEEKLERKLSEYEFASWLMYPKVFTDFAGAQETYGPVSVLPTPTYFYGMKSEDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCCC
IFIDIEKGKTLVVRCLAIGDVDDKGMVTVFFELNGQPRRVKVPDRAHGASAAKARRKAEP
EEEEECCCCEEEEEEEEECCCCCCCEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHCCC
GNEAHVGAPMPGVVSALSVATGQAVKAGDVLLSIEAMKMETALHAERDGTVAEVLVKAGD
CCCCCCCCCCHHHHHHHHHHCCCCEECCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHCCC
QIDAKDLLIAFA
CCCCCCEEEEEC
>Mature Secondary Structure 
AITKILVANRSEIAIRVFRAANELGLKTVAIWAEEDKYSLHRFKADESYQVGRGPHLTK
CCEEEEEECCCHHEEHHHHHHHHCCCEEEEEEECCCCCHHHHCCCCCCCCCCCCCCCCC
DMGPIESYLSIEEVIRVARLSGADAIHPGYGLLSESPEFAEACAQAGITFIGPKPDTMRR
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCHHHHH
LGNKVAARNLAIEVGVPVIPATDPLPDDMEAVKKLAKEIGYPVMLKASWGGGGRGMRAIR
HHHHHHHCCEEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
SEADLAREVTEGKREAKAAFGKDEVYLEKLIERARHVEVQVLGDTHGNAVHLFERDCSIQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEEEEECCCCCEEEEEECCCCHH
RRNQKVVERAPAPYLEMSQREELCGYALKIARETSYIGAGTVEFLQDADTGKFYFIEVNP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEECC
RIQVEHTVTEQVTGIDIVKAQIHILDGFAIGTPQSGVPAQKDIRLNGHALQCRITTEDPE
EEEEEEEHHHHHCCCEEEEEEEEEEECEEECCCCCCCCCCCCEEECCEEEEEEEECCCCC
HNFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRFYDPLLEKVTAWAPTPAETIARMN
CCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RALREFRIRGVATNLTFLEAIINHPSFADNSYTTKFIDTTPELFQQVKRQDRATKLLNYL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ADVSVNGHPETRGRPTPKADAAAPVVPYLNGNVPGGSKQKLDVLGPEKFAGWMREQRQVL
HHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEECCCHHHHHHHHHHCCEEE
VTDTTMRDGHQSLLATRMRTHDIANIAGTYARALPQLLSLECWGGATFDVAMRFLTEDPW
EEECCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCHH
ERLSLVREAAPNLLLQMLLRGANGVGYTNYPDNVVQHFVKQAASGGIDLFRVFDCLNWVE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NMRVAMDAVGAEGKLIEAAMCYTGDILDPARAKYDLKYYVGLASELQAAGAHIIAVKDMA
HHHHHHHHCCCCCCEEEEHHHHCCCCCCCHHHCEEEHEEECHHHHHHHCCCEEEEEHHHH
GLLKPAAARVLFKALREATDLPIHFHTHDTSGLSAATVLAAVESGVDAIDAAMDAFSGNT
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCC
SQPCLGSIVEALKGTERDPGLDPQWIRKISFYWEAVRNQYAAFESDLKGPASEVYLHEMP
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECC
GGQFTNLKEQARSLGLETRWHEVAQTYHDVNLMFGDIVKVTPSSKVVGDMALMMVSQDLT
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHEEECCEEEECCCCHHHHHHHHHHHHCCCE
VADVENPARDIAFPDSVVSMLRGDLGQSPGGWPAALQKKALKGDEPITARPGSLLKPADL
EEECCCCHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
KASRKEIEEKLERKLSEYEFASWLMYPKVFTDFAGAQETYGPVSVLPTPTYFYGMKSEDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCCC
IFIDIEKGKTLVVRCLAIGDVDDKGMVTVFFELNGQPRRVKVPDRAHGASAAKARRKAEP
EEEEECCCCEEEEEEEEECCCCCCCEEEEEEEECCCCCEEECCCCCCCCHHHHHHHHCCC
GNEAHVGAPMPGVVSALSVATGQAVKAGDVLLSIEAMKMETALHAERDGTVAEVLVKAGD
CCCCCCCCCCHHHHHHHHHHCCCCEECCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHCCC
QIDAKDLLIAFA
CCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]