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The map label for this gene is arsC [H]

Identifier: 13473384

GI number: 13473384

Start: 3169832

End: 3170341

Strand: Direct

Name: arsC [H]

Synonym: mlr3966

Alternate gene names: 13473384

Gene position: 3169832-3170341 (Clockwise)

Preceding gene: 13473382

Following gene: 13473397

Centisome position: 45.05

GC content: 59.61

Gene sequence:

>510_bases
ATGAGCGATCATGTCTACAACGTTCTCTTTCTTTGCAATGCCAATTCCGCCCGTTCGATCATGGGCGAAGCTATCTTGAA
CCGGGTCGGGGCAGGCCGCTTCAAGGCCTATTCCGCCGGTGCGCGACCGAAAGGCAGCGTCAACCCTTTTGCGCTTCAAC
TGCTGGAAAGCCTGAACTACGACACATCCTTTGCCCGCTCGAAAAGCTGGGACGAGTTCTCCAGGCCCGACGCGCCGCGG
ATGAGTTTCGTCTTCACCGTTTGCGACAACACCGCAAATGAGAGCTGCCCTGTCTGGCCCGGTCATCCGATGACGGCACT
CTGGGCGGTGCCGGATCCAGCCAAGGCCAGCGGCACCGAGGCCGAACGGCATCTCGCCTTCGCCGACGCCTATCGCATGC
TGAACAATCGCATCGCGGTGTTCACCAATCTGCCGATGGCATCACTCGATCATCTGGCCCTGCAGCAACATTTGGACGAC
ATCGGCAGGGGTGAGCCGTTGCCGAACTGA

Upstream 100 bases:

>100_bases
ACCGCGGACGGCGCAGAAATCCGCCGCCAAACCATATATGATCACGGAGCTGTGATCCGTATAGCATTCTGCCATCCGCG
CAAACATGGAGGCGTTCGAA

Downstream 100 bases:

>100_bases
ATCCGGGGCCGCCCTCTGTGACGAGGCGGTCAGACTTGAGGCAGGGATTCGTTTCCGAGCACCGCGACAACAGCGCGCTC
GACGCGCGAGCATTCCGTCA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSDHVYNVLFLCNANSARSIMGEAILNRVGAGRFKAYSAGARPKGSVNPFALQLLESLNYDTSFARSKSWDEFSRPDAPR
MSFVFTVCDNTANESCPVWPGHPMTALWAVPDPAKASGTEAERHLAFADAYRMLNNRIAVFTNLPMASLDHLALQQHLDD
IGRGEPLPN

Sequences:

>Translated_169_residues
MSDHVYNVLFLCNANSARSIMGEAILNRVGAGRFKAYSAGARPKGSVNPFALQLLESLNYDTSFARSKSWDEFSRPDAPR
MSFVFTVCDNTANESCPVWPGHPMTALWAVPDPAKASGTEAERHLAFADAYRMLNNRIAVFTNLPMASLDHLALQQHLDD
IGRGEPLPN
>Mature_168_residues
SDHVYNVLFLCNANSARSIMGEAILNRVGAGRFKAYSAGARPKGSVNPFALQLLESLNYDTSFARSKSWDEFSRPDAPRM
SFVFTVCDNTANESCPVWPGHPMTALWAVPDPAKASGTEAERHLAFADAYRMLNNRIAVFTNLPMASLDHLALQQHLDDI
GRGEPLPN

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18599; Mature: 18468

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDHVYNVLFLCNANSARSIMGEAILNRVGAGRFKAYSAGARPKGSVNPFALQLLESLNY
CCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHCCC
DTSFARSKSWDEFSRPDAPRMSFVFTVCDNTANESCPVWPGHPMTALWAVPDPAKASGTE
CCHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCH
AERHLAFADAYRMLNNRIAVFTNLPMASLDHLALQQHLDDIGRGEPLPN
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDHVYNVLFLCNANSARSIMGEAILNRVGAGRFKAYSAGARPKGSVNPFALQLLESLNY
CCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHCCC
DTSFARSKSWDEFSRPDAPRMSFVFTVCDNTANESCPVWPGHPMTALWAVPDPAKASGTE
CCHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCH
AERHLAFADAYRMLNNRIAVFTNLPMASLDHLALQQHLDDIGRGEPLPN
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]