Click here to switch to the map view.

The map label for this gene is tcyA [H]

Identifier: 13473306

GI number: 13473306

Start: 3096623

End: 3097426

Strand: Reverse

Name: tcyA [H]

Synonym: mll3861

Alternate gene names: 13473306

Gene position: 3097426-3096623 (Counterclockwise)

Preceding gene: 13473308

Following gene: 13473305

Centisome position: 44.02

GC content: 60.45

Gene sequence:

>804_bases
ATGTCAGGCCAAGGACGGGATCACAAAAAAATGAAATGGCTCAAGTCGCTTATCGTCGCCGGAACGCTGCAGGCCCTGGC
GGTCACATCAGGCCATGCCGGCGCCAATCTCGATCAGATCAAGCAGGCCGGCGTCATCAAGGTCGGTACGGAAGGCACTT
ACGCGCCCTTCACCTACCATGACGCGTCCGGCGCGCTCGTCGGCTTCGACGTGGAGATCGCCAAGGCGATCGCCGACAAG
CTCGGCGTCAAGGTCGAGTTCCTCGAAGGCAAATGGGACGGGCTGATCGCCGGTCTCGACGTCAAGCGCTACGACGCCGT
CATCAACGAGGTCGGCATCACCGACGCGCGCAAGGCCAAGTACGATTTCTCCGATCCCTACATCGCCTCCAAGGCGGTGC
TGATCGTGCGCGGCGACAACACCGACATCAAGACCTTCGCCGATCTCAAGGGCAAGAAGTCGGCGCAGTCGCTCACCTCG
AACTTCGGCAAGCTCGCCGAGGCGAGCGGCGCCGAACTGGTCGGCACCGACGGTTTCGACCAGTCGATCCAGCTGCTTTT
GACCGGCCGCGCCGATGCCACCATCAATGACAGCCTGTCGTTCCTCGACTTCAAGAAGCACAAGCCCGACGCCAATGTGA
AGATCGCCGCGCAAGAGGAAAATGCTGATTATTCCGGCGTCATCGTGCGCAAGGGCGATGCGGAACTGGTTGCCGCCATC
AACAAGGCGCTGGCCGATATCAAGGCCGACGGCACCTACAAGAAGATCGCCGACACCTATTTCGGCCAGGACGTTTCGAA
ATAA

Upstream 100 bases:

>100_bases
CATTTAGAGAATTTGGTTTCGGAAAATCTTTGTTTTTGAAATCTGGTTCCTTATTCTTTCGGCTCGCATCTGTCATTTTC
CGGCCCTCACAACAGGCCTG

Downstream 100 bases:

>100_bases
CTTTGAGTGGGGCGAGTTGTCGCTCCCGCAATGCATCCAGCGGCGGGCCGTCTTTGACGGCTCGCCGCTTTTGTCGTGAC
ATGGCCGGCGCATTCGCGCT

Product: amino acid ABC transporter, periplasmic amino acid-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSGQGRDHKKMKWLKSLIVAGTLQALAVTSGHAGANLDQIKQAGVIKVGTEGTYAPFTYHDASGALVGFDVEIAKAIADK
LGVKVEFLEGKWDGLIAGLDVKRYDAVINEVGITDARKAKYDFSDPYIASKAVLIVRGDNTDIKTFADLKGKKSAQSLTS
NFGKLAEASGAELVGTDGFDQSIQLLLTGRADATINDSLSFLDFKKHKPDANVKIAAQEENADYSGVIVRKGDAELVAAI
NKALADIKADGTYKKIADTYFGQDVSK

Sequences:

>Translated_267_residues
MSGQGRDHKKMKWLKSLIVAGTLQALAVTSGHAGANLDQIKQAGVIKVGTEGTYAPFTYHDASGALVGFDVEIAKAIADK
LGVKVEFLEGKWDGLIAGLDVKRYDAVINEVGITDARKAKYDFSDPYIASKAVLIVRGDNTDIKTFADLKGKKSAQSLTS
NFGKLAEASGAELVGTDGFDQSIQLLLTGRADATINDSLSFLDFKKHKPDANVKIAAQEENADYSGVIVRKGDAELVAAI
NKALADIKADGTYKKIADTYFGQDVSK
>Mature_266_residues
SGQGRDHKKMKWLKSLIVAGTLQALAVTSGHAGANLDQIKQAGVIKVGTEGTYAPFTYHDASGALVGFDVEIAKAIADKL
GVKVEFLEGKWDGLIAGLDVKRYDAVINEVGITDARKAKYDFSDPYIASKAVLIVRGDNTDIKTFADLKGKKSAQSLTSN
FGKLAEASGAELVGTDGFDQSIQLLLTGRADATINDSLSFLDFKKHKPDANVKIAAQEENADYSGVIVRKGDAELVAAIN
KALADIKADGTYKKIADTYFGQDVSK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=234, Percent_Identity=40.1709401709402, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787085, Length=223, Percent_Identity=34.0807174887892, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1788648, Length=231, Percent_Identity=35.4978354978355, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788649, Length=256, Percent_Identity=31.640625, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787031, Length=258, Percent_Identity=30.6201550387597, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787088, Length=228, Percent_Identity=30.2631578947368, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 28447; Mature: 28316

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQGRDHKKMKWLKSLIVAGTLQALAVTSGHAGANLDQIKQAGVIKVGTEGTYAPFTYH
CCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCEEEECCCCCCCCEEEE
DASGALVGFDVEIAKAIADKLGVKVEFLEGKWDGLIAGLDVKRYDAVINEVGITDARKAK
CCCCCEEEEHHHHHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHHHHCCCCCCHHCC
YDFSDPYIASKAVLIVRGDNTDIKTFADLKGKKSAQSLTSNFGKLAEASGAELVGTDGFD
CCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
QSIQLLLTGRADATINDSLSFLDFKKHKPDANVKIAAQEENADYSGVIVRKGDAELVAAI
CEEEEEEECCCCCEECCCCCEEEHHCCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
NKALADIKADGTYKKIADTYFGQDVSK
HHHHHHHCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGQGRDHKKMKWLKSLIVAGTLQALAVTSGHAGANLDQIKQAGVIKVGTEGTYAPFTYH
CCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCEEEECCCCCCCCEEEE
DASGALVGFDVEIAKAIADKLGVKVEFLEGKWDGLIAGLDVKRYDAVINEVGITDARKAK
CCCCCEEEEHHHHHHHHHHHHCCEEEEECCCCCCEEECCCHHHHHHHHHHCCCCCCHHCC
YDFSDPYIASKAVLIVRGDNTDIKTFADLKGKKSAQSLTSNFGKLAEASGAELVGTDGFD
CCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCC
QSIQLLLTGRADATINDSLSFLDFKKHKPDANVKIAAQEENADYSGVIVRKGDAELVAAI
CEEEEEEECCCCCEECCCCCEEEHHCCCCCCCEEEEEECCCCCCCEEEEECCCHHHHHHH
NKALADIKADGTYKKIADTYFGQDVSK
HHHHHHHCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]