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The map label for this gene is dacC [H]

Identifier: 13473090

GI number: 13473090

Start: 2885358

End: 2886527

Strand: Reverse

Name: dacC [H]

Synonym: mll3581

Alternate gene names: 13473090

Gene position: 2886527-2885358 (Counterclockwise)

Preceding gene: 13473094

Following gene: 13473089

Centisome position: 41.02

GC content: 64.44

Gene sequence:

>1170_bases
ATGCGGCACAGGCATTTCCTCAAACTATTCTCGGCTGGCGCAATCATGCTGTCGGTCCTGGCCGGGTCGGCGCTGGCCAA
TCCGGTGGTTGTCTTCGACCTGAAGAACGGCCAGATCCTGCAGCACCAGGATGCCTTCAAACGCTGGTATCCGGCCTCGC
TTAGCAAGCTGATGACCGCCTACGTGACTTTCCGGGCGATCGCTGCCGGCGAGGTCCAGCTCGATTCGCCAATCAAGGTG
ACCAAGCATTCCGCCGGCGAGCCGCCAAGCAAGATGGGGTTCAAGCCGGGCTCGGTCATGCGGCTCGACAATGCGCTGAA
GATGATGCTTGTCAAATCGGCCAATGACATCGCCATGGCGGTCGGTGAGAATGTCGGCGGCTCGCAGGCCGCCTTCGCCG
AAAGGATGAATGCCGAAGCGGCGCGGCTCGGCATGAACGGCACCCATTTCGTCAATCCGAACGGCCTCTACTCGCCCGAC
CAGTACACGACGGCGCGCGACCTTTCGGTCCTGGTGATGGCGATCCGCCGCGAGTTCCCGCAATATGCGCCATGGTTCTC
GATCGAAGGTCTTGCGGTCGGCAAGAAGGCCATTCCGAACTACAATCTCCTGATCGGCCGCTATCCCGGCGCAGACGGCA
TGAAGACAGGCTTCGTCTGTCCTTCCGGCTTCAACATGATTGGTTCGGCGACGCGCAACGGCCGCACGCTGGTCGCGGTT
GTGCTCGGCGAGAAGTCGGCGGTCAGCCGTGCCGAGGCCGCGGCAAAACTGCTCGACCAGGGGTTTGACACGCCCACGGC
CGGTTCGGCCACCGTCGCCACACTGGCGCCCTATGGCGACACGGTCTCGCCCAACGACATGCATGACGAGATCTGCAAGA
AGAAGAAAACGTCGGAGGAGCAGTCCGAGGCGCCGCCTGCGGCTGCCGCCAAGGACGCGCCGAAATCGCCCTATCAGGAA
AAGCTCGACCATGTGCCGACGCTGGTTGCCGTCGGCCTCGGCGGCGCCACCGGTCCGGCGCCGAAGGCGATGCTCGACCA
GGGTGGCCAGGAATATGCTGACGTGCCGATCCCGAACTGGCGGCCCGATCAGCCGGCGCCGACCGGCGCCGGTCCGGCCG
TTGCCGGTTCCGCCGCGCAAGGCGACCAGCCGGTCAAGGTCGCGAACTAG

Upstream 100 bases:

>100_bases
GGTCCGTTTTTGAGGGGCGGACTCATTGTGCTGGCGGTCGCGTAACGAAATCTTACGGAGCCAGGGGCAATCAGGGCAAG
AGGCGATTTCGGATTAGATC

Downstream 100 bases:

>100_bases
AGCATGATCCCGAACCGAAGGTCCGCGTCAGCGAAACTTGGAATCCGGTTTTCGGAAAAGATCATGCTCAAACAAAGAGA
CAGAGCCCGATGAATGGGTT

Product: penicillin-binding protein

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRHRHFLKLFSAGAIMLSVLAGSALANPVVVFDLKNGQILQHQDAFKRWYPASLSKLMTAYVTFRAIAAGEVQLDSPIKV
TKHSAGEPPSKMGFKPGSVMRLDNALKMMLVKSANDIAMAVGENVGGSQAAFAERMNAEAARLGMNGTHFVNPNGLYSPD
QYTTARDLSVLVMAIRREFPQYAPWFSIEGLAVGKKAIPNYNLLIGRYPGADGMKTGFVCPSGFNMIGSATRNGRTLVAV
VLGEKSAVSRAEAAAKLLDQGFDTPTAGSATVATLAPYGDTVSPNDMHDEICKKKKTSEEQSEAPPAAAAKDAPKSPYQE
KLDHVPTLVAVGLGGATGPAPKAMLDQGGQEYADVPIPNWRPDQPAPTGAGPAVAGSAAQGDQPVKVAN

Sequences:

>Translated_389_residues
MRHRHFLKLFSAGAIMLSVLAGSALANPVVVFDLKNGQILQHQDAFKRWYPASLSKLMTAYVTFRAIAAGEVQLDSPIKV
TKHSAGEPPSKMGFKPGSVMRLDNALKMMLVKSANDIAMAVGENVGGSQAAFAERMNAEAARLGMNGTHFVNPNGLYSPD
QYTTARDLSVLVMAIRREFPQYAPWFSIEGLAVGKKAIPNYNLLIGRYPGADGMKTGFVCPSGFNMIGSATRNGRTLVAV
VLGEKSAVSRAEAAAKLLDQGFDTPTAGSATVATLAPYGDTVSPNDMHDEICKKKKTSEEQSEAPPAAAAKDAPKSPYQE
KLDHVPTLVAVGLGGATGPAPKAMLDQGGQEYADVPIPNWRPDQPAPTGAGPAVAGSAAQGDQPVKVAN
>Mature_389_residues
MRHRHFLKLFSAGAIMLSVLAGSALANPVVVFDLKNGQILQHQDAFKRWYPASLSKLMTAYVTFRAIAAGEVQLDSPIKV
TKHSAGEPPSKMGFKPGSVMRLDNALKMMLVKSANDIAMAVGENVGGSQAAFAERMNAEAARLGMNGTHFVNPNGLYSPD
QYTTARDLSVLVMAIRREFPQYAPWFSIEGLAVGKKAIPNYNLLIGRYPGADGMKTGFVCPSGFNMIGSATRNGRTLVAV
VLGEKSAVSRAEAAAKLLDQGFDTPTAGSATVATLAPYGDTVSPNDMHDEICKKKKTSEEQSEAPPAAAAKDAPKSPYQE
KLDHVPTLVAVGLGGATGPAPKAMLDQGGQEYADVPIPNWRPDQPAPTGAGPAVAGSAAQGDQPVKVAN

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=295, Percent_Identity=33.8983050847458, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082022, Length=243, Percent_Identity=36.2139917695473, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1786851, Length=244, Percent_Identity=31.1475409836066, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI87082054, Length=237, Percent_Identity=29.535864978903, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 40989; Mature: 40989

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHRHFLKLFSAGAIMLSVLAGSALANPVVVFDLKNGQILQHQDAFKRWYPASLSKLMTA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHHHHHHCHHHHHHHHHH
YVTFRAIAAGEVQLDSPIKVTKHSAGEPPSKMGFKPGSVMRLDNALKMMLVKSANDIAMA
HHHHHHHCCCCEEECCCCEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEE
VGENVGGSQAAFAERMNAEAARLGMNGTHFVNPNGLYSPDQYTTARDLSVLVMAIRREFP
ECCCCCCHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
QYAPWFSIEGLAVGKKAIPNYNLLIGRYPGADGMKTGFVCPSGFNMIGSATRNGRTLVAV
CCCCCEEECCEEECHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEE
VLGEKSAVSRAEAAAKLLDQGFDTPTAGSATVATLAPYGDTVSPNDMHDEICKKKKTSEE
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHH
QSEAPPAAAAKDAPKSPYQEKLDHVPTLVAVGLGGATGPAPKAMLDQGGQEYADVPIPNW
HHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCC
RPDQPAPTGAGPAVAGSAAQGDQPVKVAN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHRHFLKLFSAGAIMLSVLAGSALANPVVVFDLKNGQILQHQDAFKRWYPASLSKLMTA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHHHHHHCHHHHHHHHHH
YVTFRAIAAGEVQLDSPIKVTKHSAGEPPSKMGFKPGSVMRLDNALKMMLVKSANDIAMA
HHHHHHHCCCCEEECCCCEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEE
VGENVGGSQAAFAERMNAEAARLGMNGTHFVNPNGLYSPDQYTTARDLSVLVMAIRREFP
ECCCCCCHHHHHHHHHCCHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
QYAPWFSIEGLAVGKKAIPNYNLLIGRYPGADGMKTGFVCPSGFNMIGSATRNGRTLVAV
CCCCCEEECCEEECHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCEEEEE
VLGEKSAVSRAEAAAKLLDQGFDTPTAGSATVATLAPYGDTVSPNDMHDEICKKKKTSEE
EECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCHH
QSEAPPAAAAKDAPKSPYQEKLDHVPTLVAVGLGGATGPAPKAMLDQGGQEYADVPIPNW
HHCCCCCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCC
RPDQPAPTGAGPAVAGSAAQGDQPVKVAN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]