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The map label for this gene is soxR [H]

Identifier: 13472428

GI number: 13472428

Start: 2185474

End: 2185920

Strand: Direct

Name: soxR [H]

Synonym: mlr2720

Alternate gene names: 13472428

Gene position: 2185474-2185920 (Clockwise)

Preceding gene: 13472427

Following gene: 13472430

Centisome position: 31.06

GC content: 65.55

Gene sequence:

>447_bases
ATGGCTCCAGCAACGGAATTGACGGTCGGCCAGGTGGCCATGCGCAGTGGTGTCGCGGTGTCGGCACTGCATTTTTATGA
GACGCGCGGGCTGATCCGCAGCCACCGCACGTCAGGCAACCAGCGGCGCTACGGCCGCGACGTGCTGCGACGGGTGGCAA
TCATCAAGGTCGCGCAGGAGGTCGGCATCTCGCTGGCCGAGATCGGCGAGGCACTTGCCTCCCTGCCGGAAGGCCGAACG
CCGACGCGCGACGACTGGAGCCTGTTGTCGACCGCCTGGCGCGACGCGCTCGACCACAAGATCACCCAGCTGAAGAAACT
GCGCGACGGGCTGACCGACTGCATCGGCTGCGGCTGCATGACGATCGACAAATGCCCGCTCAGGAACAAGGGCGACCGGC
TGGCAAGGGAGGGTACGGGAGCGAGGCGACTGTTGGTAGAATCCTAA

Upstream 100 bases:

>100_bases
ATTCTCACCCAGGCGCACATCGCCTTCTCCTGTCATTTGCCCAATCAACGTTTCTTCGCTACAAGCTCAACATAACTTGA
GGTCAAGCGGAAAATCGGAA

Downstream 100 bases:

>100_bases
TCCGCCGCCGGCAGCCGCCTGATGGTAAACTCGATCAGGTCGCCCGGGCGTTCGAACCAGCTTTCGATCTCCGTCCAGTA
GGCCTGCTTGGGGAAGCGCT

Product: transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAPATELTVGQVAMRSGVAVSALHFYETRGLIRSHRTSGNQRRYGRDVLRRVAIIKVAQEVGISLAEIGEALASLPEGRT
PTRDDWSLLSTAWRDALDHKITQLKKLRDGLTDCIGCGCMTIDKCPLRNKGDRLAREGTGARRLLVES

Sequences:

>Translated_148_residues
MAPATELTVGQVAMRSGVAVSALHFYETRGLIRSHRTSGNQRRYGRDVLRRVAIIKVAQEVGISLAEIGEALASLPEGRT
PTRDDWSLLSTAWRDALDHKITQLKKLRDGLTDCIGCGCMTIDKCPLRNKGDRLAREGTGARRLLVES
>Mature_147_residues
APATELTVGQVAMRSGVAVSALHFYETRGLIRSHRTSGNQRRYGRDVLRRVAIIKVAQEVGISLAEIGEALASLPEGRTP
TRDDWSLLSTAWRDALDHKITQLKKLRDGLTDCIGCGCMTIDKCPLRNKGDRLAREGTGARRLLVES

Specific function: Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron-sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster i

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790498, Length=138, Percent_Identity=65.2173913043478, Blast_Score=180, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR010211
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16271; Mature: 16140

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPATELTVGQVAMRSGVAVSALHFYETRGLIRSHRTSGNQRRYGRDVLRRVAIIKVAQE
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VGISLAEIGEALASLPEGRTPTRDDWSLLSTAWRDALDHKITQLKKLRDGLTDCIGCGCM
HCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TIDKCPLRNKGDRLAREGTGARRLLVES
CCCCCCCCCCCHHHHHCCCCCHHHCCCC
>Mature Secondary Structure 
APATELTVGQVAMRSGVAVSALHFYETRGLIRSHRTSGNQRRYGRDVLRRVAIIKVAQE
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VGISLAEIGEALASLPEGRTPTRDDWSLLSTAWRDALDHKITQLKKLRDGLTDCIGCGCM
HCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TIDKCPLRNKGDRLAREGTGARRLLVES
CCCCCCCCCCCHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]