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The map label for this gene is engD [H]

Identifier: 13472408

GI number: 13472408

Start: 2167531

End: 2168634

Strand: Direct

Name: engD [H]

Synonym: mlr2695

Alternate gene names: 13472408

Gene position: 2167531-2168634 (Clockwise)

Preceding gene: 13472407

Following gene: 13472409

Centisome position: 30.81

GC content: 64.67

Gene sequence:

>1104_bases
ATGGGTTTCAAATGCGGCATCGTTGGCTTGCCCAACGTCGGCAAGTCGACGCTCTTCAACGCGCTGACCAGGACGGCGGC
GGCGCAGGCCGCCAACTATCCGTTCTGCACCATCGAACCGAACACCGGCGAGGTGGCGGTGCCCGACCCGCGCTTGCAGA
AGATCGCGGCCATCGGCAAGTCGAAGGAGATCATCCCGACCCGCATCTCCTTCGTCGACATCGCCGGCCTGGTGCGCGGC
GCCTCGAAGGGCGAAGGGCTAGGCAACCAGTTCCTCGCCAACATCCGCGAGGTCGACGCCATCGTGCACGTGCTGCGCTG
CTTCGAGGATGACGACATTACCCATGTCGAGGGCCGCATCGACCCCGTCGCCGACGCCGAGACGGTCGAGACCGAGCTGA
TGCTCGCTGACCTCGACAGCCTGGAGCGCCGCATCGTCCAGATCCGCAAGCGCGCCGGCAGCAAGGACAAGGAAGCCACC
ACTGTCCTGCCGATGATGGAGGCCGCGCTCGAATTGCTGCAGGCCGGCAAGCCGACCCGCGTCCTGCTCAAGGGCATCTC
GGCCGAGGATCTGCGCATCCTGCAGGGCTTGAACTTGCTGACCTCGCACCCCGTGCTCTATGTCTGCAACGTTGGCGAAG
CCGACGCCGCGACCGGCAACGAGCACACCAGGGCCGTGGAAAAGATGGCCGCTGCTCAGGGCGCCGGCACCGTGGTGATC
TCGGCCGCGATCGAAGCCGAAGTCGCCCAGCTCTCCGACGAGGAAGAGATGGAATTCCTGTCCTCGCTCGGCCTCGACGA
GCCGGGGCTCAACAAGGTCATCCGCGCCGGTTATGAGCTTTTGCATCTTATCACCTATTTCACCGTCGGGCCGAAGGAGA
CGCGCGCCTGGACCATCCACAAGGGCGACAAGGCCCCGCAGGCGGCCGGCGTCATCCACACCGACTTCGAACGCGGCTTC
ATCCGCGCCCAGACCATCGCCTATAACGACTTCGTCACGCTGGGCGGTGAAGTGGCGGCCAAGGAAGCCGGCAAGGCGCG
CGACGAAGGCAAGGAATATGTCGTCCAGGACGGCGACATCATGCTGTTCAAGTTCAACACCTGA

Upstream 100 bases:

>100_bases
ACTGAGCGGGCCCGCATGCGGCCCTACAGGGCTTGACGTAGATCACCCCTATCGCCCATAGCCCTCATCAAATTTCGCTT
TTCCGACAGGACTGGACAAA

Downstream 100 bases:

>100_bases
CGCTCCAAGCAGCAGACGATGTCCAGCCGTCCTGCGGAAACCGGCCTGCCGAACGGGTTGCGCCAGTTGGTTTCCGGCTA
TCGCTGGCATCGGCAGACCA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGFKCGIVGLPNVGKSTLFNALTRTAAAQAANYPFCTIEPNTGEVAVPDPRLQKIAAIGKSKEIIPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIVHVLRCFEDDDITHVEGRIDPVADAETVETELMLADLDSLERRIVQIRKRAGSKDKEAT
TVLPMMEAALELLQAGKPTRVLLKGISAEDLRILQGLNLLTSHPVLYVCNVGEADAATGNEHTRAVEKMAAAQGAGTVVI
SAAIEAEVAQLSDEEEMEFLSSLGLDEPGLNKVIRAGYELLHLITYFTVGPKETRAWTIHKGDKAPQAAGVIHTDFERGF
IRAQTIAYNDFVTLGGEVAAKEAGKARDEGKEYVVQDGDIMLFKFNT

Sequences:

>Translated_367_residues
MGFKCGIVGLPNVGKSTLFNALTRTAAAQAANYPFCTIEPNTGEVAVPDPRLQKIAAIGKSKEIIPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAIVHVLRCFEDDDITHVEGRIDPVADAETVETELMLADLDSLERRIVQIRKRAGSKDKEAT
TVLPMMEAALELLQAGKPTRVLLKGISAEDLRILQGLNLLTSHPVLYVCNVGEADAATGNEHTRAVEKMAAAQGAGTVVI
SAAIEAEVAQLSDEEEMEFLSSLGLDEPGLNKVIRAGYELLHLITYFTVGPKETRAWTIHKGDKAPQAAGVIHTDFERGF
IRAQTIAYNDFVTLGGEVAAKEAGKARDEGKEYVVQDGDIMLFKFNT
>Mature_366_residues
GFKCGIVGLPNVGKSTLFNALTRTAAAQAANYPFCTIEPNTGEVAVPDPRLQKIAAIGKSKEIIPTRISFVDIAGLVRGA
SKGEGLGNQFLANIREVDAIVHVLRCFEDDDITHVEGRIDPVADAETVETELMLADLDSLERRIVQIRKRAGSKDKEATT
VLPMMEAALELLQAGKPTRVLLKGISAEDLRILQGLNLLTSHPVLYVCNVGEADAATGNEHTRAVEKMAAAQGAGTVVIS
AAIEAEVAQLSDEEEMEFLSSLGLDEPGLNKVIRAGYELLHLITYFTVGPKETRAWTIHKGDKAPQAAGVIHTDFERGFI
RAQTIAYNDFVTLGGEVAAKEAGKARDEGKEYVVQDGDIMLFKFNT

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=374, Percent_Identity=44.3850267379679, Blast_Score=302, Evalue=3e-82,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=39.0557939914163, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=58.4699453551913, Blast_Score=428, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=130, Percent_Identity=33.0769230769231, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=373, Percent_Identity=41.2868632707775, Blast_Score=283, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=40, Blast_Score=268, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.4116094986807, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=296, Percent_Identity=32.0945945945946, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640873, Length=373, Percent_Identity=41.5549597855228, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640877, Length=373, Percent_Identity=41.5549597855228, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640875, Length=373, Percent_Identity=41.5549597855228, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24640879, Length=333, Percent_Identity=39.039039039039, Blast_Score=232, Evalue=3e-61,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39556; Mature: 39424

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTRTAAAQAANYPFCTIEPNTGEVAVPDPRLQKIAAIGK
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHCC
SKEIIPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAIVHVLRCFEDDDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
DPVADAETVETELMLADLDSLERRIVQIRKRAGSKDKEATTVLPMMEAALELLQAGKPTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
VLLKGISAEDLRILQGLNLLTSHPVLYVCNVGEADAATGNEHTRAVEKMAAAQGAGTVVI
EHHCCCCHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAAIEAEVAQLSDEEEMEFLSSLGLDEPGLNKVIRAGYELLHLITYFTVGPKETRAWTIH
EHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
KGDKAPQAAGVIHTDFERGFIRAQTIAYNDFVTLGGEVAAKEAGKARDEGKEYVVQDGDI
CCCCCCCCCCCEEECCCCCEEEEEEEEECCCEECCCHHHHHHHCCCHHCCCEEEEECCCE
MLFKFNT
EEEEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTRTAAAQAANYPFCTIEPNTGEVAVPDPRLQKIAAIGK
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHCC
SKEIIPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAIVHVLRCFEDDDITHVEGRI
CCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
DPVADAETVETELMLADLDSLERRIVQIRKRAGSKDKEATTVLPMMEAALELLQAGKPTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
VLLKGISAEDLRILQGLNLLTSHPVLYVCNVGEADAATGNEHTRAVEKMAAAQGAGTVVI
EHHCCCCHHHHHHHHCCHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
SAAIEAEVAQLSDEEEMEFLSSLGLDEPGLNKVIRAGYELLHLITYFTVGPKETRAWTIH
EHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
KGDKAPQAAGVIHTDFERGFIRAQTIAYNDFVTLGGEVAAKEAGKARDEGKEYVVQDGDI
CCCCCCCCCCCEEECCCCCEEEEEEEEECCCEECCCHHHHHHHCCCHHCCCEEEEECCCE
MLFKFNT
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA