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The map label for this gene is gmhA [H]

Identifier: 13472308

GI number: 13472308

Start: 2072442

End: 2073014

Strand: Reverse

Name: gmhA [H]

Synonym: mll2561

Alternate gene names: 13472308

Gene position: 2073014-2072442 (Counterclockwise)

Preceding gene: 13472309

Following gene: 13472307

Centisome position: 29.46

GC content: 65.27

Gene sequence:

>573_bases
ATGTCTGAACTGAACGACTATCTGGTCCGCTCGGCGGCCGCGATCACGGCGATGGTCGAGCGTGACCTGACCGGCGAGAT
GGAGCGGGCGGCGAGCGCCGTGGTGACGGCGCTCTCGTCGGGTAAGGCCTTGCTGATCGCCGGCAATGGCGGTTCGGCGA
GCGACGCCATCCATATAGCCGGCGAATTGGTCGGCCGCTTCCTCAAGGAGCGCAAGGCCTACAATGTCATCGCGCTGCCG
GCCAATGCAGCGGTGCTGACGGCCTGGGGCAATGATTACGGCTTCGACACGGTGTTCTCGCGCCAGGTCGAGGCGCATGG
CACGGCCGGAGGCGTGCTCCTGGCGATCTCGACCAGCGGCAATTCGCCGAGCATCCTCGCCGCCGCCGAACAGGCGCGGA
TGATGGACATGACGGTGATCGGCCTGACCGGCGACACCGGCGGCAAACTCAAGCCGCTGTGCGACATCCTGCTCAACGTG
CCATCGACCTCGACGCCGATCATCCAGCAGGGGCATCTGTGCCTCTACCATCATCTCTGCGAAGTGGTCGAAGCGCGCCT
GTCGAATGGCTGA

Upstream 100 bases:

>100_bases
AAGGCCGGTGGGCGCGTCGTGCTGGTCGATCTCGTCGCCGGCAAGAGCACCACCGGCACAATCGGCAAATTGCGCGCCGG
CTCTACAAGCTGAGGTTTTG

Downstream 100 bases:

>100_bases
CAAGACGGGCACGCCGCACCCGCTGACCGAGCCGGGCGTGTGGATCGAGCGGATCGGCGGCCGGGTTTTCCCGCCGCACC
TGCCGGCGCTGTTCCTCGAC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MSELNDYLVRSAAAITAMVERDLTGEMERAASAVVTALSSGKALLIAGNGGSASDAIHIAGELVGRFLKERKAYNVIALP
ANAAVLTAWGNDYGFDTVFSRQVEAHGTAGGVLLAISTSGNSPSILAAAEQARMMDMTVIGLTGDTGGKLKPLCDILLNV
PSTSTPIIQQGHLCLYHHLCEVVEARLSNG

Sequences:

>Translated_190_residues
MSELNDYLVRSAAAITAMVERDLTGEMERAASAVVTALSSGKALLIAGNGGSASDAIHIAGELVGRFLKERKAYNVIALP
ANAAVLTAWGNDYGFDTVFSRQVEAHGTAGGVLLAISTSGNSPSILAAAEQARMMDMTVIGLTGDTGGKLKPLCDILLNV
PSTSTPIIQQGHLCLYHHLCEVVEARLSNG
>Mature_189_residues
SELNDYLVRSAAAITAMVERDLTGEMERAASAVVTALSSGKALLIAGNGGSASDAIHIAGELVGRFLKERKAYNVIALPA
NAAVLTAWGNDYGFDTVFSRQVEAHGTAGGVLLAISTSGNSPSILAAAEQARMMDMTVIGLTGDTGGKLKPLCDILLNVP
STSTPIIQQGHLCLYHHLCEVVEARLSNG

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=168, Percent_Identity=41.6666666666667, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786416, Length=162, Percent_Identity=41.358024691358, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 19739; Mature: 19608

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELNDYLVRSAAAITAMVERDLTGEMERAASAVVTALSSGKALLIAGNGGSASDAIHIA
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHH
GELVGRFLKERKAYNVIALPANAAVLTAWGNDYGFDTVFSRQVEAHGTAGGVLLAISTSG
HHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEECC
NSPSILAAAEQARMMDMTVIGLTGDTGGKLKPLCDILLNVPSTSTPIIQQGHLCLYHHLC
CCCEEEEHHHHHHEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHH
EVVEARLSNG
HHHHHHHCCC
>Mature Secondary Structure 
SELNDYLVRSAAAITAMVERDLTGEMERAASAVVTALSSGKALLIAGNGGSASDAIHIA
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHH
GELVGRFLKERKAYNVIALPANAAVLTAWGNDYGFDTVFSRQVEAHGTAGGVLLAISTSG
HHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEECC
NSPSILAAAEQARMMDMTVIGLTGDTGGKLKPLCDILLNVPSTSTPIIQQGHLCLYHHLC
CCCEEEEHHHHHHEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHCCCCHHHHHHH
EVVEARLSNG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA