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The map label for this gene is gmhB [H]

Identifier: 13472307

GI number: 13472307

Start: 2071796

End: 2072449

Strand: Reverse

Name: gmhB [H]

Synonym: mll2559

Alternate gene names: 13472307

Gene position: 2072449-2071796 (Counterclockwise)

Preceding gene: 13472308

Following gene: 13472304

Centisome position: 29.45

GC content: 68.04

Gene sequence:

>654_bases
ATGGCTGACAAGACGGGCACGCCGCACCCGCTGACCGAGCCGGGCGTGTGGATCGAGCGGATCGGCGGCCGGGTTTTCCC
GCCGCACCTGCCGGCGCTGTTCCTCGACCGCGACGGCACCATCAACGTCGATACCGACTATCCCAGCGACCCGGCCGAAA
TTGTGCTCAGGCCGCAGATGCTACCGGCGATCGCAACCGCCAACCGGGCGGGAATCCCGGTTGTCGTGGTCACCAACCAG
TCCGGCATCGCGCGCGGTTATTTCGGCTGGAGCGCCTTTGCGGCGGTGAATGGCCGCGTGCTCGAGCTGTTGCGCGAGGA
GGGCGTGTTCGTCGACATGGTGCTTGCCTGCGCCTATCACGAGGCCGGTGTCGGGCCACTCGCCATCCCGGATCATCCGA
TGCGCAAGCCCAATCCGGGCATGCTGGTCGAGGCGGGCAAACGCCTGGCTCTCGATCTCCAGCGCTCGCTGATCGTCGGC
GACAAGCTTGCCGACATGCAGGCGGGAAAGCGCGCCGGTCTCGCACAGGGCTGGCTGGTCGACGGCGAGGCGGCGGTCCA
GCCCGGCTTCGCCATCAGGCCCCTGCGGGACAGCAGCGAGCTCGGTGACCTGCTCGCAGCCATTGAAACGCTCGGCCGGG
ACAACAGGTCCTGA

Upstream 100 bases:

>100_bases
ATCCTGCTCAACGTGCCATCGACCTCGACGCCGATCATCCAGCAGGGGCATCTGTGCCTCTACCATCATCTCTGCGAAGT
GGTCGAAGCGCGCCTGTCGA

Downstream 100 bases:

>100_bases
TCCAGGCCCGACCGCTCACACGGGATCGTCGCGTTCCGAGGCTTCGTAGAGCTTTGCCTCCGTGGCGAAGGAATAGATCA
TCACCGACATCGAGTAGACG

Product: hypothetical protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MADKTGTPHPLTEPGVWIERIGGRVFPPHLPALFLDRDGTINVDTDYPSDPAEIVLRPQMLPAIATANRAGIPVVVVTNQ
SGIARGYFGWSAFAAVNGRVLELLREEGVFVDMVLACAYHEAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVG
DKLADMQAGKRAGLAQGWLVDGEAAVQPGFAIRPLRDSSELGDLLAAIETLGRDNRS

Sequences:

>Translated_217_residues
MADKTGTPHPLTEPGVWIERIGGRVFPPHLPALFLDRDGTINVDTDYPSDPAEIVLRPQMLPAIATANRAGIPVVVVTNQ
SGIARGYFGWSAFAAVNGRVLELLREEGVFVDMVLACAYHEAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVG
DKLADMQAGKRAGLAQGWLVDGEAAVQPGFAIRPLRDSSELGDLLAAIETLGRDNRS
>Mature_216_residues
ADKTGTPHPLTEPGVWIERIGGRVFPPHLPALFLDRDGTINVDTDYPSDPAEIVLRPQMLPAIATANRAGIPVVVVTNQS
GIARGYFGWSAFAAVNGRVLELLREEGVFVDMVLACAYHEAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVGD
KLADMQAGKRAGLAQGWLVDGEAAVQPGFAIRPLRDSSELGDLLAAIETLGRDNRS

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=151, Percent_Identity=39.0728476821192, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI87082027, Length=146, Percent_Identity=26.027397260274, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 23200; Mature: 23069

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKTGTPHPLTEPGVWIERIGGRVFPPHLPALFLDRDGTINVDTDYPSDPAEIVLRPQM
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCCHHHEEECCHH
LPAIATANRAGIPVVVVTNQSGIARGYFGWSAFAAVNGRVLELLREEGVFVDMVLACAYH
HHHHHCCCCCCCEEEEEECCCCCEECCCCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH
EAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVGDKLADMQAGKRAGLAQGWLV
HCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEE
DGEAAVQPGFAIRPLRDSSELGDLLAAIETLGRDNRS
CCHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADKTGTPHPLTEPGVWIERIGGRVFPPHLPALFLDRDGTINVDTDYPSDPAEIVLRPQM
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCCHHHEEECCHH
LPAIATANRAGIPVVVVTNQSGIARGYFGWSAFAAVNGRVLELLREEGVFVDMVLACAYH
HHHHHCCCCCCCEEEEEECCCCCEECCCCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH
EAGVGPLAIPDHPMRKPNPGMLVEAGKRLALDLQRSLIVGDKLADMQAGKRAGLAQGWLV
HCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEE
DGEAAVQPGFAIRPLRDSSELGDLLAAIETLGRDNRS
CCHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11279237; 12101286 [H]