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The map label for this gene is trxB [H]

Identifier: 13472304

GI number: 13472304

Start: 2069049

End: 2070023

Strand: Reverse

Name: trxB [H]

Synonym: mll2552

Alternate gene names: 13472304

Gene position: 2070023-2069049 (Counterclockwise)

Preceding gene: 13472307

Following gene: 13472303

Centisome position: 29.42

GC content: 65.85

Gene sequence:

>975_bases
ATGACCACCAAGCACGCGCCCGTTCTCATCATAGGTTCCGGTCCGGCCGGCTATACGGCGGCGGTCTATGCCGCGCGCGC
CATGCTGAAGCCGATGCTGGTTGCCGGCCTGCAGCAGGGCGGCCAGCTGATGATCACCACCGATGTCGAAAATTATCCCG
GCTTCGCCGATCCCATCCAGGGGCCGTGGCTGATGGAACAGATGATGAAGCAGGCCGAGCATGTCGGCACCGACATCATC
AACGACATCATCACCGAGGTCGACCTCAACGTGCGGCCGTTTCGCGCCAAGGGCGATTCCGGCACCACCTACACCGCCGA
CGCGCTGATCATCGCCACCGGCGCGCAGGCCAAGTGGCTGGGCATTCCGACCGAGCAGGATTTCATGGGCTTCGGCGTCT
CGGCCTGCGCCACCTGTGACGGCTTCTTCTATCGCGGCAAGGATGTCGCGGTGGTCGGCGGCGGCAATTCGGCGGTGGAG
GAGGCACTGTATCTGTCGAACCTCGCCAAGAGCGTCACGGTCATCCATCGGCGCAGCGACTTCCGCGCCGAGCGCATCTT
GCGCGAGCGGCTGCTGCAGAAGGACAATGTCCGCGTCATCTGGGACACGGTGGTCGACGAGATCACCGGCCGCCCCGGCA
AGGCGCCGCTGCCGCCGTCGGTCGAAGGGCTGAAGCTCAAGCATGCGGTGACCGGTGCCGAAACGCACCTCAAGGTCGAC
GGCGTGTTCGTGGCGATCGGCCATGCGCCGGCGGTCGAGCTGTTCGTCGGCAAGCTGAAGCAGAAGCCGAACGGTTATCT
GTGGACGGCGCCGAATTCGACCCGCACCGACGTGCCCGGCGTGTTCGCGGCCGGCGACGTGACCGACGATGTCTACCGCC
AGGCGGTGACGGCGGCGGGGCTCGGCTGCATGGCGGCACTCGAAGCGGAAAAGTATCTGGCCGGCATCGAGGTGCATCGC
GAGGCAGCGGAATAG

Upstream 100 bases:

>100_bases
CGACGGCCCGTTCGTCTTGCTGGCGTGGTTGGCAACCCTTACATTAAGCGCGAATTCCACGTCTTTTCCCAAGGCACTGT
CTGCCCCGCAGAGGTTTTAG

Downstream 100 bases:

>100_bases
GAGCCGCTTTAAACTGTTAAAAAAACGGCTTAGAAACGTCGTGTAAAAGCCTGATTTTTCATTCAGACGCCAAACAGAAC
GAGGGGAATCATGGCGTTGG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTTKHAPVLIIGSGPAGYTAAVYAARAMLKPMLVAGLQQGGQLMITTDVENYPGFADPIQGPWLMEQMMKQAEHVGTDII
NDIITEVDLNVRPFRAKGDSGTTYTADALIIATGAQAKWLGIPTEQDFMGFGVSACATCDGFFYRGKDVAVVGGGNSAVE
EALYLSNLAKSVTVIHRRSDFRAERILRERLLQKDNVRVIWDTVVDEITGRPGKAPLPPSVEGLKLKHAVTGAETHLKVD
GVFVAIGHAPAVELFVGKLKQKPNGYLWTAPNSTRTDVPGVFAAGDVTDDVYRQAVTAAGLGCMAALEAEKYLAGIEVHR
EAAE

Sequences:

>Translated_324_residues
MTTKHAPVLIIGSGPAGYTAAVYAARAMLKPMLVAGLQQGGQLMITTDVENYPGFADPIQGPWLMEQMMKQAEHVGTDII
NDIITEVDLNVRPFRAKGDSGTTYTADALIIATGAQAKWLGIPTEQDFMGFGVSACATCDGFFYRGKDVAVVGGGNSAVE
EALYLSNLAKSVTVIHRRSDFRAERILRERLLQKDNVRVIWDTVVDEITGRPGKAPLPPSVEGLKLKHAVTGAETHLKVD
GVFVAIGHAPAVELFVGKLKQKPNGYLWTAPNSTRTDVPGVFAAGDVTDDVYRQAVTAAGLGCMAALEAEKYLAGIEVHR
EAAE
>Mature_323_residues
TTKHAPVLIIGSGPAGYTAAVYAARAMLKPMLVAGLQQGGQLMITTDVENYPGFADPIQGPWLMEQMMKQAEHVGTDIIN
DIITEVDLNVRPFRAKGDSGTTYTADALIIATGAQAKWLGIPTEQDFMGFGVSACATCDGFFYRGKDVAVVGGGNSAVEE
ALYLSNLAKSVTVIHRRSDFRAERILRERLLQKDNVRVIWDTVVDEITGRPGKAPLPPSVEGLKLKHAVTGAETHLKVDG
VFVAIGHAPAVELFVGKLKQKPNGYLWTAPNSTRTDVPGVFAAGDVTDDVYRQAVTAAGLGCMAALEAEKYLAGIEVHRE
AAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=323, Percent_Identity=55.4179566563467, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI87081763, Length=313, Percent_Identity=33.2268370607029, Blast_Score=138, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321898, Length=323, Percent_Identity=45.2012383900929, Blast_Score=279, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=43.6532507739938, Blast_Score=270, Evalue=3e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34666; Mature: 34535

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKHAPVLIIGSGPAGYTAAVYAARAMLKPMLVAGLQQGGQLMITTDVENYPGFADPIQ
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWLMEQMMKQAEHVGTDIINDIITEVDLNVRPFRAKGDSGTTYTADALIIATGAQAKWL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEECCCCCCEEEECEEEEEECCCEEEE
GIPTEQDFMGFGVSACATCDGFFYRGKDVAVVGGGNSAVEEALYLSNLAKSVTVIHRRSD
CCCCCCHHHCCCHHHHHHHCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCH
FRAERILRERLLQKDNVRVIWDTVVDEITGRPGKAPLPPSVEGLKLKHAVTGAETHLKVD
HHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
GVFVAIGHAPAVELFVGKLKQKPNGYLWTAPNSTRTDVPGVFAAGDVTDDVYRQAVTAAG
EEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHC
LGCMAALEAEKYLAGIEVHREAAE
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTKHAPVLIIGSGPAGYTAAVYAARAMLKPMLVAGLQQGGQLMITTDVENYPGFADPIQ
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWLMEQMMKQAEHVGTDIINDIITEVDLNVRPFRAKGDSGTTYTADALIIATGAQAKWL
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECEEECCCCCCEEEECEEEEEECCCEEEE
GIPTEQDFMGFGVSACATCDGFFYRGKDVAVVGGGNSAVEEALYLSNLAKSVTVIHRRSD
CCCCCCHHHCCCHHHHHHHCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCH
FRAERILRERLLQKDNVRVIWDTVVDEITGRPGKAPLPPSVEGLKLKHAVTGAETHLKVD
HHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEE
GVFVAIGHAPAVELFVGKLKQKPNGYLWTAPNSTRTDVPGVFAAGDVTDDVYRQAVTAAG
EEEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHC
LGCMAALEAEKYLAGIEVHREAAE
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA