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The map label for this gene is yafC [H]

Identifier: 13472303

GI number: 13472303

Start: 2068062

End: 2068958

Strand: Reverse

Name: yafC [H]

Synonym: mll2551

Alternate gene names: 13472303

Gene position: 2068958-2068062 (Counterclockwise)

Preceding gene: 13472304

Following gene: 13472299

Centisome position: 29.41

GC content: 63.43

Gene sequence:

>897_bases
ATGGCGTTGGACTGGGACAAGCTACGCGTGTTTCACGCTGCGGCGGAAGCGGGATCGTTTACGCACGCGGCCGAGACATT
GCACCTGTCGCAATCGGCGATCTCGCGGCAGGTCAGTGCGCTCGAGCACGATGTCGGCGTGCCGCTGTTCAACCGCCATG
CACGCGGCCTGGTGCTGACCGAACAGGGCGAGATGCTGTTCCGCACGGCGCATGACGTGCTGATGAAGCTCGAGACCATC
AAGTCGCGCCTGACCGAGACCAAGGACCGGCCCTCCGGCGTGCTTCGCGTGACGACGACCGTTGGCCTCGGCGCCGGCTG
GCTGACCGAACGGGTGCAGGAGTTCATCGAACTCTATCCCGAGATCAGCCTGCAGCTGATCCTCGCCAATGAGGAGCTCG
ACCTCACCATGCGCCAGGCCGATTGCGCCATCCGGCTGCGCCAGCCGCAGCAGCCGGACCTGATCCAGCGCCGCCTGTTC
ACCGTGCATTTCCACCTCTATGCGGCGCCCTCCTATGTCGCCAAGCATGGCAAGCCGGCCTCGGTCTCGGAGTTGAGGAA
CCATCGTATCGTCACCTTCGGCCTGCCGGTGCCGTCGCATCTGTCGGAGTTGAACTGGCTGGAGACGGTCGGCGATTTCG
AGGGCGGCCAGCGCGTGCCGTCGCTGCAGATCAACGACATCTTGTCGATCAAGCGCGCCGTGCAGGGCGGCGCCGGCATC
GCCATGCTGCCCGACTATGTGATCAACAAGGACTCCGGACTGGTGCAGCTTTTGCCGGAAACCGAGGTGCCATCCTTCGA
CACCTATTTCGCCTATCCAGACGCGATGAAGAACCAGGCCAAGCTGCACGTGTTCCGCGACTTCATCATTGCCAAGGCCA
GAAGCTGGTCCTTCTAG

Upstream 100 bases:

>100_bases
AGCGGAATAGGAGCCGCTTTAAACTGTTAAAAAAACGGCTTAGAAACGTCGTGTAAAAGCCTGATTTTTCATTCAGACGC
CAAACAGAACGAGGGGAATC

Downstream 100 bases:

>100_bases
GATATGTCGATATTCAGGTGAGGCCGGCCTGCGAACGTGAGTTTCCTGCGCTTCCGGTACTCACGGACGGAAAGTCCGCT
CCGTTCCGGTTCACGGAAAC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MALDWDKLRVFHAAAEAGSFTHAAETLHLSQSAISRQVSALEHDVGVPLFNRHARGLVLTEQGEMLFRTAHDVLMKLETI
KSRLTETKDRPSGVLRVTTTVGLGAGWLTERVQEFIELYPEISLQLILANEELDLTMRQADCAIRLRQPQQPDLIQRRLF
TVHFHLYAAPSYVAKHGKPASVSELRNHRIVTFGLPVPSHLSELNWLETVGDFEGGQRVPSLQINDILSIKRAVQGGAGI
AMLPDYVINKDSGLVQLLPETEVPSFDTYFAYPDAMKNQAKLHVFRDFIIAKARSWSF

Sequences:

>Translated_298_residues
MALDWDKLRVFHAAAEAGSFTHAAETLHLSQSAISRQVSALEHDVGVPLFNRHARGLVLTEQGEMLFRTAHDVLMKLETI
KSRLTETKDRPSGVLRVTTTVGLGAGWLTERVQEFIELYPEISLQLILANEELDLTMRQADCAIRLRQPQQPDLIQRRLF
TVHFHLYAAPSYVAKHGKPASVSELRNHRIVTFGLPVPSHLSELNWLETVGDFEGGQRVPSLQINDILSIKRAVQGGAGI
AMLPDYVINKDSGLVQLLPETEVPSFDTYFAYPDAMKNQAKLHVFRDFIIAKARSWSF
>Mature_297_residues
ALDWDKLRVFHAAAEAGSFTHAAETLHLSQSAISRQVSALEHDVGVPLFNRHARGLVLTEQGEMLFRTAHDVLMKLETIK
SRLTETKDRPSGVLRVTTTVGLGAGWLTERVQEFIELYPEISLQLILANEELDLTMRQADCAIRLRQPQQPDLIQRRLFT
VHFHLYAAPSYVAKHGKPASVSELRNHRIVTFGLPVPSHLSELNWLETVGDFEGGQRVPSLQINDILSIKRAVQGGAGIA
MLPDYVINKDSGLVQLLPETEVPSFDTYFAYPDAMKNQAKLHVFRDFIIAKARSWSF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=31.3993174061433, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789440, Length=295, Percent_Identity=27.4576271186441, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=27.9863481228669, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=25.5813953488372, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787589, Length=272, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787128, Length=297, Percent_Identity=27.2727272727273, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=26.2798634812287, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI157672245, Length=184, Percent_Identity=32.0652173913043, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789173, Length=295, Percent_Identity=25.7627118644068, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788706, Length=180, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786448, Length=124, Percent_Identity=36.2903225806452, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786713, Length=87, Percent_Identity=42.5287356321839, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=25.938566552901, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790262, Length=271, Percent_Identity=26.5682656826568, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789204, Length=126, Percent_Identity=30.952380952381, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788296, Length=197, Percent_Identity=26.3959390862944, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787530, Length=109, Percent_Identity=34.8623853211009, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33460; Mature: 33329

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDWDKLRVFHAAAEAGSFTHAAETLHLSQSAISRQVSALEHDVGVPLFNRHARGLVLT
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
EQGEMLFRTAHDVLMKLETIKSRLTETKDRPSGVLRVTTTVGLGAGWLTERVQEFIELYP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCC
EISLQLILANEELDLTMRQADCAIRLRQPQQPDLIQRRLFTVHFHLYAAPSYVAKHGKPA
CCEEEEEEECCCCCEEEECCCEEEEECCCCCCCHHHHHHHEEEEEEEECHHHHHHCCCCC
SVSELRNHRIVTFGLPVPSHLSELNWLETVGDFEGGQRVPSLQINDILSIKRAVQGGAGI
CHHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCCCE
AMLPDYVINKDSGLVQLLPETEVPSFDTYFAYPDAMKNQAKLHVFRDFIIAKARSWSF
EECCHHEECCCCCEEEECCCCCCCCCCCEECCCHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ALDWDKLRVFHAAAEAGSFTHAAETLHLSQSAISRQVSALEHDVGVPLFNRHARGLVLT
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
EQGEMLFRTAHDVLMKLETIKSRLTETKDRPSGVLRVTTTVGLGAGWLTERVQEFIELYP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCC
EISLQLILANEELDLTMRQADCAIRLRQPQQPDLIQRRLFTVHFHLYAAPSYVAKHGKPA
CCEEEEEEECCCCCEEEECCCEEEEECCCCCCCHHHHHHHEEEEEEEECHHHHHHCCCCC
SVSELRNHRIVTFGLPVPSHLSELNWLETVGDFEGGQRVPSLQINDILSIKRAVQGGAGI
CHHHHHCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCCCE
AMLPDYVINKDSGLVQLLPETEVPSFDTYFAYPDAMKNQAKLHVFRDFIIAKARSWSF
EECCHHEECCCCCEEEECCCCCCCCCCCEECCCHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]