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The map label for this gene is coxS [H]

Identifier: 13472100

GI number: 13472100

Start: 1848284

End: 1848760

Strand: Reverse

Name: coxS [H]

Synonym: mll2289

Alternate gene names: 13472100

Gene position: 1848760-1848284 (Counterclockwise)

Preceding gene: 13472101

Following gene: 13472099

Centisome position: 26.28

GC content: 65.62

Gene sequence:

>477_bases
ATGGCTGGCATTGCAGTCTCGACGACAATCAACGGCGACAATATCGAGTATCTCTGCCAGCCTGACGAGACGCTGCTCGA
CGTGCTGCGCGACCGGCTCGGCCTGACCGGCGCCAAGGAAGGCTGCGGCACCGGCGACTGCGGCGCCTGCAGCATCATCC
TCGACGACCGGCTGGTCTGCTCCTGCCTGGTGCTGGGCGCCGAGGCCGAAGGCCGGCGCATCGAGACCGTCGAAGGCATG
GCGCATGGCGACCAGCTGCACACGCTGCAGCAGAAATTCCTCGAGCACGCGGCCCTGCAATGCGGCATCTGCACGCCGGG
TTTCCTGATCGCGGCCAAGGATCTGCTGGCGAAAAACCCCGACCCGACCGAGGAGGAAATCCGCTTCGGCCTCGCCGGCA
ATCTCTGCCGCTGCACCGGCTATGACAAGATCGTGCGCGCCGTCCAGGACGCCGCAATTGTGATGAAGGGAGCCTGA

Upstream 100 bases:

>100_bases
TCGACGACAAGCGCGGTACCATCGAATTCAGACGCAAAGTTGCGGGCGTGCTGGCCAGGAGAGCCGCCACGACCGCCTAC
GCACGTGCAGGAGGCAAATA

Downstream 100 bases:

>100_bases
AGATGAATTTCGATCCGCGTTTTTCCGGGCGTAAATTCGCATCCGTCGGCACGCGCCCCATCCGCCCCGACGGCGTCGAC
AAGGTGACGGGCCGCGCCCG

Product: carbon-monoxide dehydrogenase small chain

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAGIAVSTTINGDNIEYLCQPDETLLDVLRDRLGLTGAKEGCGTGDCGACSIILDDRLVCSCLVLGAEAEGRRIETVEGM
AHGDQLHTLQQKFLEHAALQCGICTPGFLIAAKDLLAKNPDPTEEEIRFGLAGNLCRCTGYDKIVRAVQDAAIVMKGA

Sequences:

>Translated_158_residues
MAGIAVSTTINGDNIEYLCQPDETLLDVLRDRLGLTGAKEGCGTGDCGACSIILDDRLVCSCLVLGAEAEGRRIETVEGM
AHGDQLHTLQQKFLEHAALQCGICTPGFLIAAKDLLAKNPDPTEEEIRFGLAGNLCRCTGYDKIVRAVQDAAIVMKGA
>Mature_157_residues
AGIAVSTTINGDNIEYLCQPDETLLDVLRDRLGLTGAKEGCGTGDCGACSIILDDRLVCSCLVLGAEAEGRRIETVEGMA
HGDQLHTLQQKFLEHAALQCGICTPGFLIAAKDLLAKNPDPTEEEIRFGLAGNLCRCTGYDKIVRAVQDAAIVMKGA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=155, Percent_Identity=39.3548387096774, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI71773480, Length=90, Percent_Identity=36.6666666666667, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789232, Length=149, Percent_Identity=46.3087248322148, Blast_Score=128, Evalue=2e-31,
Organism=Escherichia coli, GI1786480, Length=164, Percent_Identity=35.3658536585366, Blast_Score=111, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=159, Percent_Identity=40.251572327044, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17539860, Length=150, Percent_Identity=40.6666666666667, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32566215, Length=150, Percent_Identity=39.3333333333333, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=35.5263157894737, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24647197, Length=147, Percent_Identity=34.0136054421769, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647195, Length=147, Percent_Identity=34.0136054421769, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24647201, Length=162, Percent_Identity=34.5679012345679, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24647199, Length=141, Percent_Identity=34.7517730496454, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24647193, Length=166, Percent_Identity=33.7349397590361, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 16751; Mature: 16620

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
6.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIAVSTTINGDNIEYLCQPDETLLDVLRDRLGLTGAKEGCGTGDCGACSIILDDRLVC
CCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHH
SCLVLGAEAEGRRIETVEGMAHGDQLHTLQQKFLEHAALQCGICTPGFLIAAKDLLAKNP
HHHHCCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DPTEEEIRFGLAGNLCRCTGYDKIVRAVQDAAIVMKGA
CCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
AGIAVSTTINGDNIEYLCQPDETLLDVLRDRLGLTGAKEGCGTGDCGACSIILDDRLVC
CCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHH
SCLVLGAEAEGRRIETVEGMAHGDQLHTLQQKFLEHAALQCGICTPGFLIAAKDLLAKNP
HHHHCCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DPTEEEIRFGLAGNLCRCTGYDKIVRAVQDAAIVMKGA
CCCHHHHHHCCCCCEEEECCHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]