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The map label for this gene is ccpA [H]

Identifier: 13472066

GI number: 13472066

Start: 1804837

End: 1805832

Strand: Direct

Name: ccpA [H]

Synonym: mlr2242

Alternate gene names: 13472066

Gene position: 1804837-1805832 (Clockwise)

Preceding gene: 13472061

Following gene: 13472067

Centisome position: 25.65

GC content: 69.08

Gene sequence:

>996_bases
TTGCGTGACGTGGCGGCGCGGGCCGGCGTCAGCGTTGCCACCGCCTCGAAGGCGCTCAACGACCAGGGGCGGATGACCGC
CGAGACGCGCGAGCGCATCCGCGAGACGGCGCGCAGCCTCGGCTTCCGGCCCAACAGCCTGGCGCAGAGCCTGCTCAGGC
GCCGCTCCTTCACCGTCGGCCTGCTCACCAACGATACTTACGGCCGCTTCTCGCTGCCGCTGATGTCGGGCATTTCGGAC
GCGCTGGTCGACAATGGCGTCTCGGTGTTCCTGTGCAATGTCGAGGAGGATCCGCGGCTGGGCCAGCTGCATGTCGAGGC
CATGCTCGACAAGCGCGTCGACGGCATCATCGCTACGGGAAAACGCATCGACCGCCATCTGCCCGTCGATCTCGCCAATC
TGCGCATCCCGGTGATCTATGCCTTCACCCAGCCCGATCCCGACGCCGTCGCCTTCGTCTCGGACGATGCCGGCGGCGCG
CGGCTGGCGGTCGAGCATTTCTGCCGGCTCGGCCGCAGGCGCATCGCCCATGTCAGTGGGCCGGCGAGCTTTGCCGTGGT
GCACGCCCGCGCCCAGGCCTATCGCGACGTGCTCGCCGAAAACGGCCTGCCGGTCACCGAGCCGCTGCTCGGCGCCTGGT
CGGAAGCCTGGGGACATGAAGCGGTGGCGCAATTGTTCGACGGCAAAAGCCAACGGCCGGACGCCGTCTTTTGCGGCAAC
GATCAGATCGCGCGCGGCGTCATTGACGCCCTGCGCGAGCGCGGCCTCGACGTTCCCGGCGATGTCGGCGTCATCGGTTT
CGACAATTGGGAGATCGTCGCGGAAGCGACGCGCCCGCCGCTGACCTCGGTCGACATGAACCTGGTCGCCCTCGGCCGCG
AGGCCGGGCTGACCCTGCTTTCCCTGGTCGGCGGTCGGCCCGCCGCGCCGGGCATTCGAAAACTGCCGTGCCGGCTGGTG
GTACGGCGTTCCTGCGGCCATCCGCTGGATGGCTGA

Upstream 100 bases:

>100_bases
GGGCCTTGTTCCGGTCTGTAAGAGAAAACCTTTTCCCAACTAAGGATTCTCGATGGCAGCGGACGATCAGCCTGTTCCGG
TCTTTCCCAAGCCCGTCACC

Downstream 100 bases:

>100_bases
AACGACGCGCCGCGTGATCGGCGCCAAGCCGCGGATAGCGGCCAACCCTGGAGGAGGAGAAGATGAGGAACGTGATTGCC
AAACTGGCCCTGGCCGCTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRDVAARAGVSVATASKALNDQGRMTAETRERIRETARSLGFRPNSLAQSLLRRRSFTVGLLTNDTYGRFSLPLMSGISD
ALVDNGVSVFLCNVEEDPRLGQLHVEAMLDKRVDGIIATGKRIDRHLPVDLANLRIPVIYAFTQPDPDAVAFVSDDAGGA
RLAVEHFCRLGRRRIAHVSGPASFAVVHARAQAYRDVLAENGLPVTEPLLGAWSEAWGHEAVAQLFDGKSQRPDAVFCGN
DQIARGVIDALRERGLDVPGDVGVIGFDNWEIVAEATRPPLTSVDMNLVALGREAGLTLLSLVGGRPAAPGIRKLPCRLV
VRRSCGHPLDG

Sequences:

>Translated_331_residues
MRDVAARAGVSVATASKALNDQGRMTAETRERIRETARSLGFRPNSLAQSLLRRRSFTVGLLTNDTYGRFSLPLMSGISD
ALVDNGVSVFLCNVEEDPRLGQLHVEAMLDKRVDGIIATGKRIDRHLPVDLANLRIPVIYAFTQPDPDAVAFVSDDAGGA
RLAVEHFCRLGRRRIAHVSGPASFAVVHARAQAYRDVLAENGLPVTEPLLGAWSEAWGHEAVAQLFDGKSQRPDAVFCGN
DQIARGVIDALRERGLDVPGDVGVIGFDNWEIVAEATRPPLTSVDMNLVALGREAGLTLLSLVGGRPAAPGIRKLPCRLV
VRRSCGHPLDG
>Mature_331_residues
MRDVAARAGVSVATASKALNDQGRMTAETRERIRETARSLGFRPNSLAQSLLRRRSFTVGLLTNDTYGRFSLPLMSGISD
ALVDNGVSVFLCNVEEDPRLGQLHVEAMLDKRVDGIIATGKRIDRHLPVDLANLRIPVIYAFTQPDPDAVAFVSDDAGGA
RLAVEHFCRLGRRRIAHVSGPASFAVVHARAQAYRDVLAENGLPVTEPLLGAWSEAWGHEAVAQLFDGKSQRPDAVFCGN
DQIARGVIDALRERGLDVPGDVGVIGFDNWEIVAEATRPPLTSVDMNLVALGREAGLTLLSLVGGRPAAPGIRKLPCRLV
VRRSCGHPLDG

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=331, Percent_Identity=29.9093655589124, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790194, Length=301, Percent_Identity=30.5647840531561, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786540, Length=332, Percent_Identity=29.5180722891566, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789202, Length=334, Percent_Identity=29.3413173652695, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789068, Length=342, Percent_Identity=29.5321637426901, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=27.9635258358663, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788474, Length=307, Percent_Identity=28.6644951140065, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787906, Length=311, Percent_Identity=30.8681672025724, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790715, Length=320, Percent_Identity=26.25, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787580, Length=321, Percent_Identity=23.6760124610592, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789456, Length=361, Percent_Identity=25.7617728531856, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786268, Length=332, Percent_Identity=22.8915662650602, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790689, Length=316, Percent_Identity=22.7848101265823, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35677; Mature: 35677

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDVAARAGVSVATASKALNDQGRMTAETRERIRETARSLGFRPNSLAQSLLRRRSFTVG
CCCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEE
LLTNDTYGRFSLPLMSGISDALVDNGVSVFLCNVEEDPRLGQLHVEAMLDKRVDGIIATG
EEECCCCCEEECHHHHCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCEECCC
KRIDRHLPVDLANLRIPVIYAFTQPDPDAVAFVSDDAGGARLAVEHFCRLGRRRIAHVSG
HHHHCCCCEEHHCCEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
PASFAVVHARAQAYRDVLAENGLPVTEPLLGAWSEAWGHEAVAQLFDGKSQRPDAVFCGN
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
DQIARGVIDALRERGLDVPGDVGVIGFDNWEIVAEATRPPLTSVDMNLVALGREAGLTLL
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCEEEEECHHHCHHHH
SLVGGRPAAPGIRKLPCRLVVRRSCGHPLDG
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRDVAARAGVSVATASKALNDQGRMTAETRERIRETARSLGFRPNSLAQSLLRRRSFTVG
CCCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEE
LLTNDTYGRFSLPLMSGISDALVDNGVSVFLCNVEEDPRLGQLHVEAMLDKRVDGIIATG
EEECCCCCEEECHHHHCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCEECCC
KRIDRHLPVDLANLRIPVIYAFTQPDPDAVAFVSDDAGGARLAVEHFCRLGRRRIAHVSG
HHHHCCCCEEHHCCEEEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEECCC
PASFAVVHARAQAYRDVLAENGLPVTEPLLGAWSEAWGHEAVAQLFDGKSQRPDAVFCGN
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
DQIARGVIDALRERGLDVPGDVGVIGFDNWEIVAEATRPPLTSVDMNLVALGREAGLTLL
HHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCEEEEECHHHCHHHH
SLVGGRPAAPGIRKLPCRLVVRRSCGHPLDG
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]