BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

Click here to switch to the map view.

The map label for this gene is fabG [C]

Identifier: 13471612

GI number: 13471612

Start: 1359404

End: 1360243

Strand: Direct

Name: fabG [C]

Synonym: mlr1637

Alternate gene names: 13471612

Gene position: 1359404-1360243 (Clockwise)

Preceding gene: 13471610

Following gene: 13471613

Centisome position: 19.32

GC content: 66.19

Gene sequence:

>840_bases
ATGGACCTGAAAGACAAGACAATCCTTATAACTGGCTCGACCGACGGCGTCGGCCGCGTCGTCGCGCAAAGGCTGGGCGC
CGACGGCGCCCGGGTGCTGGTGCATGGCCGCGATGCGGCGCGCGGCAAGGCAGCGGTCGCCGAGATCGAAGCGGCTGGGG
GCAGAGCCGAGTTCTTCGCCGCCGACCTCGCCTCGCTGGCCGAAATTCGCCACCTCGCCGAGGCGGTACGTGCCCGAACG
AACCGGCTCGATATCCTCATCAACAATGCCGGCATCGGCACGGCAGCCGCCAAGCGGCAGGTCAGTGCCGATGGCTACGA
ACTGCGCTTCGCCGTCAACTATCTCGCCGGTTTCCTGCTGACCTCGGAGCTTCTGCCGCTGCTGAAGGCCAGCGCCCCGG
CGCGCATCGTCAATGTCGCCTCGGCCGGCCAGCAAGCGATCGACTTCGGCGACGTGATGCTCACCCACGGCTATAGCGGC
GTACGCGCCTATTGCCAGAGCAAGCTGGCGCAAATCCTGTTCACCGTCGATCTGGCGGAACAGCTGAAAGGCACCGGCGT
CACCGTCAACGCGCTGCATCCGGCGAGCTACATGAACACCACCATGGTCCGGCAGGCCGGCGTGACGCCATGGAGCTCGG
TCGAAACCGGCGCCGAAGCCATCGTCAACCTTGCCGCCTCACCCGCGCTCGAAGGCCGCAGCGGCCTCTATTTCGACGGA
CTGCGCGAAGCCCGCGCCGATGCCCAGGCCTACGACGCCACGGCAAGACAACAATTGCGAAGCCTCAGCCGCGACCTTGT
CGGCGCGGCCTCCTCAAAATCCAGGGAACGGCACTCATGA

Upstream 100 bases:

>100_bases
CTTATTATAGCAGTATTGATACCAGGATAAAGTTTGAACTGTTTGAGATCGGCCAGACGTCCCATCTTGCATCTGGAGCA
GCAGACAGGAGGCTCTGGAC

Downstream 100 bases:

>100_bases
CCAACAGAACAGAACACACAGTCATCATCGGCGGCTCATCCGGCATCGGCCTGGCAACCGCGCGAAAATTGCTCGGCCCG
GGCATGAAGGTGACGATCAC

Product: hypothetical protein

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDLKDKTILITGSTDGVGRVVAQRLGADGARVLVHGRDAARGKAAVAEIEAAGGRAEFFAADLASLAEIRHLAEAVRART
NRLDILINNAGIGTAAAKRQVSADGYELRFAVNYLAGFLLTSELLPLLKASAPARIVNVASAGQQAIDFGDVMLTHGYSG
VRAYCQSKLAQILFTVDLAEQLKGTGVTVNALHPASYMNTTMVRQAGVTPWSSVETGAEAIVNLAASPALEGRSGLYFDG
LREARADAQAYDATARQQLRSLSRDLVGAASSKSRERHS

Sequences:

>Translated_279_residues
MDLKDKTILITGSTDGVGRVVAQRLGADGARVLVHGRDAARGKAAVAEIEAAGGRAEFFAADLASLAEIRHLAEAVRART
NRLDILINNAGIGTAAAKRQVSADGYELRFAVNYLAGFLLTSELLPLLKASAPARIVNVASAGQQAIDFGDVMLTHGYSG
VRAYCQSKLAQILFTVDLAEQLKGTGVTVNALHPASYMNTTMVRQAGVTPWSSVETGAEAIVNLAASPALEGRSGLYFDG
LREARADAQAYDATARQQLRSLSRDLVGAASSKSRERHS
>Mature_279_residues
MDLKDKTILITGSTDGVGRVVAQRLGADGARVLVHGRDAARGKAAVAEIEAAGGRAEFFAADLASLAEIRHLAEAVRART
NRLDILINNAGIGTAAAKRQVSADGYELRFAVNYLAGFLLTSELLPLLKASAPARIVNVASAGQQAIDFGDVMLTHGYSG
VRAYCQSKLAQILFTVDLAEQLKGTGVTVNALHPASYMNTTMVRQAGVTPWSSVETGAEAIVNLAASPALEGRSGLYFDG
LREARADAQAYDATARQQLRSLSRDLVGAASSKSRERHS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=295, Percent_Identity=37.6271186440678, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI166795268, Length=281, Percent_Identity=35.5871886120996, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI186928839, Length=281, Percent_Identity=35.9430604982206, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI10190746, Length=296, Percent_Identity=37.1621621621622, Blast_Score=147, Evalue=8e-36,
Organism=Homo sapiens, GI7706523, Length=287, Percent_Identity=32.404181184669, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI19923931, Length=237, Percent_Identity=40.5063291139241, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI193804850, Length=285, Percent_Identity=32.9824561403509, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI146231950, Length=286, Percent_Identity=35.6643356643357, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI142976729, Length=220, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502599, Length=266, Percent_Identity=27.8195488721804, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40254986, Length=208, Percent_Identity=25.9615384615385, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4502601, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=219, Percent_Identity=25.1141552511416, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=200, Percent_Identity=28.5, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558006, Length=284, Percent_Identity=30.9859154929577, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17532791, Length=289, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193207620, Length=299, Percent_Identity=29.7658862876254, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17532805, Length=265, Percent_Identity=30.188679245283, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17505416, Length=290, Percent_Identity=28.9655172413793, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI193203115, Length=239, Percent_Identity=30.1255230125523, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=235, Percent_Identity=30.2127659574468, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71992402, Length=261, Percent_Identity=27.9693486590038, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32565532, Length=219, Percent_Identity=30.5936073059361, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI115533174, Length=290, Percent_Identity=31.3793103448276, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71982365, Length=202, Percent_Identity=27.7227722772277, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533172, Length=290, Percent_Identity=31.3793103448276, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=216, Percent_Identity=28.2407407407407, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558628, Length=204, Percent_Identity=27.9411764705882, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=163, Percent_Identity=30.0613496932515, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=201, Percent_Identity=31.3432835820896, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72001364, Length=290, Percent_Identity=26.2068965517241, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=33.1632653061224, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535059, Length=261, Percent_Identity=26.0536398467433, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=198, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=295, Percent_Identity=26.1016949152542, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45554248, Length=256, Percent_Identity=39.453125, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24640117, Length=256, Percent_Identity=39.453125, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573296, Length=268, Percent_Identity=36.9402985074627, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19921754, Length=291, Percent_Identity=33.6769759450172, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24586328, Length=277, Percent_Identity=35.3790613718412, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI22024069, Length=281, Percent_Identity=33.4519572953737, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI161076371, Length=255, Percent_Identity=36.8627450980392, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45553409, Length=267, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24647948, Length=267, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24647946, Length=264, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI20129347, Length=287, Percent_Identity=29.616724738676, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24656154, Length=282, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI19922628, Length=282, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24647931, Length=276, Percent_Identity=31.8840579710145, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357673, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=193, Percent_Identity=32.1243523316062, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21357041, Length=208, Percent_Identity=30.2884615384615, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=29.8969072164948, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=208, Percent_Identity=28.3653846153846, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24644339, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643142, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 29394; Mature: 29394

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKDKTILITGSTDGVGRVVAQRLGADGARVLVHGRDAARGKAAVAEIEAAGGRAEFFA
CCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHH
ADLASLAEIRHLAEAVRARTNRLDILINNAGIGTAAAKRQVSADGYELRFAVNYLAGFLL
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHH
TSELLPLLKASAPARIVNVASAGQQAIDFGDVMLTHGYSGVRAYCQSKLAQILFTVDLAE
HHHHHHHHHCCCCHHEEEHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QLKGTGVTVNALHPASYMNTTMVRQAGVTPWSSVETGAEAIVNLAASPALEGRSGLYFDG
HHCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LREARADAQAYDATARQQLRSLSRDLVGAASSKSRERHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDLKDKTILITGSTDGVGRVVAQRLGADGARVLVHGRDAARGKAAVAEIEAAGGRAEFFA
CCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCHHHHH
ADLASLAEIRHLAEAVRARTNRLDILINNAGIGTAAAKRQVSADGYELRFAVNYLAGFLL
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCEEEEHHHHHHHHHHH
TSELLPLLKASAPARIVNVASAGQQAIDFGDVMLTHGYSGVRAYCQSKLAQILFTVDLAE
HHHHHHHHHCCCCHHEEEHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QLKGTGVTVNALHPASYMNTTMVRQAGVTPWSSVETGAEAIVNLAASPALEGRSGLYFDG
HHCCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LREARADAQAYDATARQQLRSLSRDLVGAASSKSRERHS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]