Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 13471609

GI number: 13471609

Start: 1356217

End: 1357545

Strand: Reverse

Name: ygjG [C]

Synonym: mll1632

Alternate gene names: 13471609

Gene position: 1357545-1356217 (Counterclockwise)

Preceding gene: 13471611

Following gene: 13471608

Centisome position: 19.29

GC content: 63.66

Gene sequence:

>1329_bases
ATGTCCAACCGGCTGAAAGTCACGCCGAACGATCTCAGCGCATTCTGGATGCCGTTCACGGCAAACCGGCAGTTCAAACA
GGCGCCGCGTATGTTCGTGTCCGCCAAGGACATGCATTACACCACCAGCGATGGCCGCAAGGTGCTGGACGGCACCGCCG
GTCTGTGGTGCGTCAACGCCGGCCACTGCCGGCCGAAGATCACCGAGGCGATCCAGCACCAGGCCGCCGAACTCGATTAC
GCGCCGGCCTTCCAGATGGGTCACCCGATCGTGTTCGAGCTGGCCAACCGCCTGGTCGACATCGCACCCAAGGGCATGGA
CCATGTCTTCTTCACCAATTCCGGTTCGGAATCGGTCGAGACGGCGCTGAAAATGGCGATCGCCTATCACCGCATGAAGG
GCGAGGGCGCGCGCACCCGCCTGATCGGCCGCGAGCGCGGCTATCACGGCGTCAACTTCGGCGGCATCTCGGTCGGCGGC
ATCGTCTCCAACCGCAAGATGTTCGGCACGCTGCTCGGCGGCGTCGACCACATGCCGCACACGCATCTGCCGGAAAAGAA
CGCTTTCTCGAAGGGCGTGCCGGAATATGGCGCGGAGCTCGCCAACGAACTGGAGCGCATCGTCGCCCTGCATGACGCCT
CGACCATCGCCGCCGTCATTGTCGAGCCGGTCGCCGGCTCCACCGGTGTCATCCTGCCGCCCAAGGGCTATCTGCAGAAG
CTGCGCGAAATCTGCACCAAGCACGGCATCCTTTTGATATTCGACGAGGTCATCACCGGTTTCGGCCGTCTCGGCGCGCC
GTTCGCGGCCGACTATTTCGGTGTGGTTCCCGATATCATGACCACCGCCAAGGGCGTCTCCAACGGCGTCATCCCGATGG
GCGCGGTGTTCGTGAAGAAGGAAATCCACGACGCCTTCATGACCGGCCCCGAGCACATGATCGAGTTCTTCCACGGCTAC
ACCTATTCGGGCAATCCGATCGCCTGCGCCGCGGCCTTGGGCACGCTCGACACCTACAAGGAAGAGGGCCTGCTCACCCG
TGGCGAGGAACTGGCGCCCTATTGGGAGGACGCGTTGCATTCGCTGAAGGGCGAGCCGCATGTCATCGACATCAGGAACA
TCGGCCTGATCGGCGCGATCGAACTGGCGCCGATCGCCGGCAGCCCGACCAAGCGGGCCTTCTCGGCCTTCGTCAAGGCG
TTCGAGCGCGGCGCGCTGATCCGCACCACCGGCGACATCATCGCGCTGTCGCCGCCGCTGATCATCACCAAGGGCCAGAT
CAACGAACTGATCGACCATGTGCGTGAAGTGCTGCGGTCGATCGACTAG

Upstream 100 bases:

>100_bases
TAACGTTTGTCCAATCGGTCAAAAATTTGCGTAGCATGAAAACGGCGCAAAGACCAAGCGTTGGACGCACCGAAACAGGT
TACAAGGGGAAGTCTTGGTC

Downstream 100 bases:

>100_bases
CCTGGTCTATAAATCGGGCGGCGTTGGGAACCGCCGTCCGATTTTGAATGAAATGGAAGGATTTTGAATGGCCGCACCCG
GCGAGAATCTGCGAATCAAT

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSNRLKVTPNDLSAFWMPFTANRQFKQAPRMFVSAKDMHYTTSDGRKVLDGTAGLWCVNAGHCRPKITEAIQHQAAELDY
APAFQMGHPIVFELANRLVDIAPKGMDHVFFTNSGSESVETALKMAIAYHRMKGEGARTRLIGRERGYHGVNFGGISVGG
IVSNRKMFGTLLGGVDHMPHTHLPEKNAFSKGVPEYGAELANELERIVALHDASTIAAVIVEPVAGSTGVILPPKGYLQK
LREICTKHGILLIFDEVITGFGRLGAPFAADYFGVVPDIMTTAKGVSNGVIPMGAVFVKKEIHDAFMTGPEHMIEFFHGY
TYSGNPIACAAALGTLDTYKEEGLLTRGEELAPYWEDALHSLKGEPHVIDIRNIGLIGAIELAPIAGSPTKRAFSAFVKA
FERGALIRTTGDIIALSPPLIITKGQINELIDHVREVLRSID

Sequences:

>Translated_442_residues
MSNRLKVTPNDLSAFWMPFTANRQFKQAPRMFVSAKDMHYTTSDGRKVLDGTAGLWCVNAGHCRPKITEAIQHQAAELDY
APAFQMGHPIVFELANRLVDIAPKGMDHVFFTNSGSESVETALKMAIAYHRMKGEGARTRLIGRERGYHGVNFGGISVGG
IVSNRKMFGTLLGGVDHMPHTHLPEKNAFSKGVPEYGAELANELERIVALHDASTIAAVIVEPVAGSTGVILPPKGYLQK
LREICTKHGILLIFDEVITGFGRLGAPFAADYFGVVPDIMTTAKGVSNGVIPMGAVFVKKEIHDAFMTGPEHMIEFFHGY
TYSGNPIACAAALGTLDTYKEEGLLTRGEELAPYWEDALHSLKGEPHVIDIRNIGLIGAIELAPIAGSPTKRAFSAFVKA
FERGALIRTTGDIIALSPPLIITKGQINELIDHVREVLRSID
>Mature_441_residues
SNRLKVTPNDLSAFWMPFTANRQFKQAPRMFVSAKDMHYTTSDGRKVLDGTAGLWCVNAGHCRPKITEAIQHQAAELDYA
PAFQMGHPIVFELANRLVDIAPKGMDHVFFTNSGSESVETALKMAIAYHRMKGEGARTRLIGRERGYHGVNFGGISVGGI
VSNRKMFGTLLGGVDHMPHTHLPEKNAFSKGVPEYGAELANELERIVALHDASTIAAVIVEPVAGSTGVILPPKGYLQKL
REICTKHGILLIFDEVITGFGRLGAPFAADYFGVVPDIMTTAKGVSNGVIPMGAVFVKKEIHDAFMTGPEHMIEFFHGYT
YSGNPIACAAALGTLDTYKEEGLLTRGEELAPYWEDALHSLKGEPHVIDIRNIGLIGAIELAPIAGSPTKRAFSAFVKAF
ERGALIRTTGDIIALSPPLIITKGQINELIDHVREVLRSID

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=416, Percent_Identity=30.0480769230769, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI284507298, Length=331, Percent_Identity=31.4199395770393, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=431, Percent_Identity=29.0023201856148, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28.4705882352941, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI226442709, Length=395, Percent_Identity=29.3670886075949, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI226442705, Length=427, Percent_Identity=28.3372365339578, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=433, Percent_Identity=26.0969976905312, Blast_Score=122, Evalue=7e-28,
Organism=Escherichia coli, GI145693181, Length=404, Percent_Identity=31.9306930693069, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1786991, Length=438, Percent_Identity=31.2785388127854, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=30.5418719211823, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788044, Length=411, Percent_Identity=28.2238442822384, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789016, Length=419, Percent_Identity=28.8782816229117, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787560, Length=417, Percent_Identity=29.0167865707434, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786349, Length=340, Percent_Identity=29.7058823529412, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI32564660, Length=424, Percent_Identity=30.8962264150943, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=393, Percent_Identity=29.7709923664122, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI71992977, Length=437, Percent_Identity=28.8329519450801, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=245, Percent_Identity=32.6530612244898, Blast_Score=121, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6323470, Length=436, Percent_Identity=29.8165137614679, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324386, Length=498, Percent_Identity=26.7068273092369, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324432, Length=413, Percent_Identity=29.5399515738499, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321456, Length=311, Percent_Identity=25.4019292604502, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357415, Length=402, Percent_Identity=30.0995024875622, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI161085790, Length=471, Percent_Identity=28.0254777070064, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574759, Length=464, Percent_Identity=28.6637931034483, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21356575, Length=446, Percent_Identity=29.8206278026906, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281366494, Length=430, Percent_Identity=24.4186046511628, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24667139, Length=430, Percent_Identity=24.4186046511628, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24667143, Length=430, Percent_Identity=24.4186046511628, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48056; Mature: 47925

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRLKVTPNDLSAFWMPFTANRQFKQAPRMFVSAKDMHYTTSDGRKVLDGTAGLWCVNA
CCCCEECCCCCCCEEEECCCCCCHHHHHHHHHEECCCCEEECCCCCEEECCCCCEEEEEC
GHCRPKITEAIQHQAAELDYAPAFQMGHPIVFELANRLVDIAPKGMDHVFFTNSGSESVE
CCCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHH
TALKMAIAYHRMKGEGARTRLIGRERGYHGVNFGGISVGGIVSNRKMFGTLLGGVDHMPH
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEECCEECCHHHHHHHHCCCCCCCC
THLPEKNAFSKGVPEYGAELANELERIVALHDASTIAAVIVEPVAGSTGVILPPKGYLQK
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCHHHEEHHHEECCCCCCCEEECCHHHHHH
LREICTKHGILLIFDEVITGFGRLGAPFAADYFGVVPDIMTTAKGVSNGVIPMGAVFVKK
HHHHHHHCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
EIHDAFMTGPEHMIEFFHGYTYSGNPIACAAALGTLDTYKEEGLLTRGEELAPYWEDALH
HHHHHHHCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SLKGEPHVIDIRNIGLIGAIELAPIAGSPTKRAFSAFVKAFERGALIRTTGDIIALSPPL
HHCCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEECCCE
IITKGQINELIDHVREVLRSID
EEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNRLKVTPNDLSAFWMPFTANRQFKQAPRMFVSAKDMHYTTSDGRKVLDGTAGLWCVNA
CCCEECCCCCCCEEEECCCCCCHHHHHHHHHEECCCCEEECCCCCEEECCCCCEEEEEC
GHCRPKITEAIQHQAAELDYAPAFQMGHPIVFELANRLVDIAPKGMDHVFFTNSGSESVE
CCCCHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHH
TALKMAIAYHRMKGEGARTRLIGRERGYHGVNFGGISVGGIVSNRKMFGTLLGGVDHMPH
HHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCEEECCEECCHHHHHHHHCCCCCCCC
THLPEKNAFSKGVPEYGAELANELERIVALHDASTIAAVIVEPVAGSTGVILPPKGYLQK
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHCHHHEEHHHEECCCCCCCEEECCHHHHHH
LREICTKHGILLIFDEVITGFGRLGAPFAADYFGVVPDIMTTAKGVSNGVIPMGAVFVKK
HHHHHHHCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
EIHDAFMTGPEHMIEFFHGYTYSGNPIACAAALGTLDTYKEEGLLTRGEELAPYWEDALH
HHHHHHHCCHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SLKGEPHVIDIRNIGLIGAIELAPIAGSPTKRAFSAFVKAFERGALIRTTGDIIALSPPL
HHCCCCCEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCEEEECCCE
IITKGQINELIDHVREVLRSID
EEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]