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The map label for this gene is hflK [H]

Identifier: 13471474

GI number: 13471474

Start: 1213266

End: 1214381

Strand: Reverse

Name: hflK [H]

Synonym: mll1455

Alternate gene names: 13471474

Gene position: 1214381-1213266 (Counterclockwise)

Preceding gene: 13471475

Following gene: 13471473

Centisome position: 17.26

GC content: 66.22

Gene sequence:

>1116_bases
ATGCCCTGGAACGACAAGAGTGGCGGAGGCGGCGGCCCGTGGGGCGGCGGCGGTAACAATCAGGGGCCCTGGGGGCAGGG
GCCAAAGGGGCCAAGCGGCCCGCAAGGGTCGCCCCCCGACCTCGAAGACATTATCCGCCGCGGCCAGGATCGGCTGCGGC
GCGCTCTGCCCGGCGGCGGTGGCGCCAGTCCGGCGGTGTTCGGGCTGATCGCCGCGGTGCTGGTCGCTCTGTGGGCATTC
CAGGCAGTCTATACGGTGCAGCCCGACGAGGTCGCGGTCGAACTGCGCTTCGGCAAGCCGAAGGCCGAACTCTCCCAGCC
TGGCCTGCATTTCCATTGGTGGCCGCTTGAAACCGTCGAAACGGCGAAGATTTCCGAGCAGCTCGTCGACATTGGCGGCG
GCAACACCAGCGGCAATGGCCTGATGCTTTCGGGCGACCAGAACATCGTCAACGTGCAGTTTTCGGTGGCCTACCAGGTC
TCCGATCCCCGCGCCTATCTGTTCGACGTCTCGGATCCGGACGGCATGCTGCGGCAGGTTGCCGAAAGCGCCATGCGCGA
AGCCGTCGGCCGCCGGCCGGCACAGGACATCTTCCGCGATGACCGCCAGGGCATAGCCGCGTCGGTCCGCGAAATCATCC
AGTCGACGCTGGACGGCTACAAGGCCGGTCTCAACGTCAATGCCGTGTCGATCGAGGATGCGGCACCGCCACGCGAAGTG
GCCGATGCGTTCGACGAGGTGCAGCGTGCCGAGCAGGACGAGGACAAGTTCGTCGAGCAGGCCAACCAGTATTCCAACCA
GAAGCTCGGCCAGGCGCGCGGCCAGGCGGCACAGATCCGCGAAGACGCGGCCGCCTACAAGAACCGCGTCGTGCAGGAAG
CCGAAGGTGAGGCCCAGCGCTTCATCTCGGTCTATGACGAATACGCCAAGGCCCCGGATGTCACCCGCAAGCGCCTCTAT
CTGGAAACCATGGAGAGGGTTCTGAAGGACTCGAGCAAGGTCATCGTCGAGCAGGGCAACGGACAAGGTGTCGTGCCTTA
TCTGCCGCTGCCGGCATTGCAGCCGAAACCGCCGGCTCCGGCCGCGCCTGCCGCGAACACGGGAGGTACCCAGTGA

Upstream 100 bases:

>100_bases
CATCGCGTTGAAAGCGTGCCGTGGCGTCCCTATAGAAGAACAACACTGGATTTGCGCCGTAACTCCGGCGCTTGAGGGAA
TTCCAAGCGAAAGGACATTC

Downstream 100 bases:

>100_bases
TGGCCAACCGTCTTCCCATTTTCGTCGTCATCGCGGCGGTCATCCTGTTCCTGATCTATTCCTCGGTCTTCGTGGTCAAT
GCGCGCCAGCAAGCGCTGGT

Product: protease subunit hflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPWNDKSGGGGGPWGGGGNNQGPWGQGPKGPSGPQGSPPDLEDIIRRGQDRLRRALPGGGGASPAVFGLIAAVLVALWAF
QAVYTVQPDEVAVELRFGKPKAELSQPGLHFHWWPLETVETAKISEQLVDIGGGNTSGNGLMLSGDQNIVNVQFSVAYQV
SDPRAYLFDVSDPDGMLRQVAESAMREAVGRRPAQDIFRDDRQGIAASVREIIQSTLDGYKAGLNVNAVSIEDAAPPREV
ADAFDEVQRAEQDEDKFVEQANQYSNQKLGQARGQAAQIREDAAAYKNRVVQEAEGEAQRFISVYDEYAKAPDVTRKRLY
LETMERVLKDSSKVIVEQGNGQGVVPYLPLPALQPKPPAPAAPAANTGGTQ

Sequences:

>Translated_371_residues
MPWNDKSGGGGGPWGGGGNNQGPWGQGPKGPSGPQGSPPDLEDIIRRGQDRLRRALPGGGGASPAVFGLIAAVLVALWAF
QAVYTVQPDEVAVELRFGKPKAELSQPGLHFHWWPLETVETAKISEQLVDIGGGNTSGNGLMLSGDQNIVNVQFSVAYQV
SDPRAYLFDVSDPDGMLRQVAESAMREAVGRRPAQDIFRDDRQGIAASVREIIQSTLDGYKAGLNVNAVSIEDAAPPREV
ADAFDEVQRAEQDEDKFVEQANQYSNQKLGQARGQAAQIREDAAAYKNRVVQEAEGEAQRFISVYDEYAKAPDVTRKRLY
LETMERVLKDSSKVIVEQGNGQGVVPYLPLPALQPKPPAPAAPAANTGGTQ
>Mature_370_residues
PWNDKSGGGGGPWGGGGNNQGPWGQGPKGPSGPQGSPPDLEDIIRRGQDRLRRALPGGGGASPAVFGLIAAVLVALWAFQ
AVYTVQPDEVAVELRFGKPKAELSQPGLHFHWWPLETVETAKISEQLVDIGGGNTSGNGLMLSGDQNIVNVQFSVAYQVS
DPRAYLFDVSDPDGMLRQVAESAMREAVGRRPAQDIFRDDRQGIAASVREIIQSTLDGYKAGLNVNAVSIEDAAPPREVA
DAFDEVQRAEQDEDKFVEQANQYSNQKLGQARGQAAQIREDAAAYKNRVVQEAEGEAQRFISVYDEYAKAPDVTRKRLYL
ETMERVLKDSSKVIVEQGNGQGVVPYLPLPALQPKPPAPAAPAANTGGTQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=388, Percent_Identity=33.7628865979381, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 39840; Mature: 39709

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWNDKSGGGGGPWGGGGNNQGPWGQGPKGPSGPQGSPPDLEDIIRRGQDRLRRALPGGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GASPAVFGLIAAVLVALWAFQAVYTVQPDEVAVELRFGKPKAELSQPGLHFHWWPLETVE
CCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHCCCCCEEEECCCCHHH
TAKISEQLVDIGGGNTSGNGLMLSGDQNIVNVQFSVAYQVSDPRAYLFDVSDPDGMLRQV
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCEEEEECCCCHHHHHHH
AESAMREAVGRRPAQDIFRDDRQGIAASVREIIQSTLDGYKAGLNVNAVSIEDAAPPREV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
ADAFDEVQRAEQDEDKFVEQANQYSNQKLGQARGQAAQIREDAAAYKNRVVQEAEGEAQR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FISVYDEYAKAPDVTRKRLYLETMERVLKDSSKVIVEQGNGQGVVPYLPLPALQPKPPAP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCCCCCCCCC
AAPAANTGGTQ
CCCCCCCCCCC
>Mature Secondary Structure 
PWNDKSGGGGGPWGGGGNNQGPWGQGPKGPSGPQGSPPDLEDIIRRGQDRLRRALPGGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GASPAVFGLIAAVLVALWAFQAVYTVQPDEVAVELRFGKPKAELSQPGLHFHWWPLETVE
CCCHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCHHHHCCCCCEEEECCCCHHH
TAKISEQLVDIGGGNTSGNGLMLSGDQNIVNVQFSVAYQVSDPRAYLFDVSDPDGMLRQV
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCEEEEECCCCHHHHHHH
AESAMREAVGRRPAQDIFRDDRQGIAASVREIIQSTLDGYKAGLNVNAVSIEDAAPPREV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
ADAFDEVQRAEQDEDKFVEQANQYSNQKLGQARGQAAQIREDAAAYKNRVVQEAEGEAQR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FISVYDEYAKAPDVTRKRLYLETMERVLKDSSKVIVEQGNGQGVVPYLPLPALQPKPPAP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEECCCCCCCCCCCCCCCC
AAPAANTGGTQ
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]