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The map label for this gene is nahR [H]

Identifier: 13471227

GI number: 13471227

Start: 956087

End: 956977

Strand: Reverse

Name: nahR [H]

Synonym: mll1141

Alternate gene names: 13471227

Gene position: 956977-956087 (Counterclockwise)

Preceding gene: 13471229

Following gene: 13471225

Centisome position: 13.6

GC content: 68.69

Gene sequence:

>891_bases
ATGACAACACCCGATCTCAATCTGCTCTTTGCTCTCGACGTGCTGCTGGCCGAAGGCAGCGTGGCCCGCGCCGCGCGCCG
TCTGCGGCTCAGCCCCTCGGCGATGAGCCGAACGCTGGCGCGGCTGCGCGAGGCGACGGGCGATCCTTTGCTGGTGCGGG
CCGGCCGCGGCCTGGTGGCGACGCCGCGCGCGGAGGAATTGCGCCGCCAGGTCGGTACTGTCGTCCAGGACGCGGAGGCG
CTCCTGCGCCCCGCCGAATTGCTTGATCTCTCAACCCTGGACAGGGTCTTCACGCTGCGCACCAACGAAGGCTTCGTCGA
GGAGTTCGGGCCTTGCCTCGTCGCCCGCATCGGGGCCGAAGCGCCAGAGGTGCGGCTGCGTTTCGCGCCGAAGTCCGACA
AGGATGTGATGTCGCTACGCGACGCGGCGATCGACCTGGAAATCGGCGTTGCCGGCGAAACCGGGCCCGAAGTGCGCATC
CAGGCACTGTTTCGCGACCGCTTCATCGGCGCTGTTCGAGCCGGCCATCCCCTGAGCAAGGGCACGGTGACGCCCGAGCG
ATACGCCGCTGGCCGGCACATCAGCGTTTCGCGGCGCGGCCGCGAGAAAGGGCCGATCGACGAGGCTTTGGGTGGGCTTG
GCTTGCGGCGGATGGTGGTGTGCATGGTCTCGGGTTTCTCAGCCGCGCTCGCCATGGCGCGCGCCTCGGAGCTGATCGCA
AGCGTACCCGAGCGGCACACGGCCGGCGCGCGCGCCGGCATGTACAGTTTTCGGCTGCCGGTCACGACGGTGGAAGTCAC
CATTTCGATGCTCTGGCATCCGCGCCTCGATGCCGACCCGGCGCAACGCTGGTTGCGCGAATGCGTGCGGGAGGTCTGTG
CAAGTCGGTGA

Upstream 100 bases:

>100_bases
TGGAGCCGATGGAGATCTAGTCTTTCGGCTGATATGGCGGAAGGTGCAGTATTTGCATCATATCAGTGCATGAGACGCCA
CATCATGCTACGATCCGCGG

Downstream 100 bases:

>100_bases
GATCAGCGCGCCATCGCCGCCTCGAGCACCTTGAAAATCCGCTGGTCTTCGCACTGGGCGACATTGAAGCGCAGGAAATG
GCTGGCCGTCCGGGACAGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTTPDLNLLFALDVLLAEGSVARAARRLRLSPSAMSRTLARLREATGDPLLVRAGRGLVATPRAEELRRQVGTVVQDAEA
LLRPAELLDLSTLDRVFTLRTNEGFVEEFGPCLVARIGAEAPEVRLRFAPKSDKDVMSLRDAAIDLEIGVAGETGPEVRI
QALFRDRFIGAVRAGHPLSKGTVTPERYAAGRHISVSRRGREKGPIDEALGGLGLRRMVVCMVSGFSAALAMARASELIA
SVPERHTAGARAGMYSFRLPVTTVEVTISMLWHPRLDADPAQRWLRECVREVCASR

Sequences:

>Translated_296_residues
MTTPDLNLLFALDVLLAEGSVARAARRLRLSPSAMSRTLARLREATGDPLLVRAGRGLVATPRAEELRRQVGTVVQDAEA
LLRPAELLDLSTLDRVFTLRTNEGFVEEFGPCLVARIGAEAPEVRLRFAPKSDKDVMSLRDAAIDLEIGVAGETGPEVRI
QALFRDRFIGAVRAGHPLSKGTVTPERYAAGRHISVSRRGREKGPIDEALGGLGLRRMVVCMVSGFSAALAMARASELIA
SVPERHTAGARAGMYSFRLPVTTVEVTISMLWHPRLDADPAQRWLRECVREVCASR
>Mature_295_residues
TTPDLNLLFALDVLLAEGSVARAARRLRLSPSAMSRTLARLREATGDPLLVRAGRGLVATPRAEELRRQVGTVVQDAEAL
LRPAELLDLSTLDRVFTLRTNEGFVEEFGPCLVARIGAEAPEVRLRFAPKSDKDVMSLRDAAIDLEIGVAGETGPEVRIQ
ALFRDRFIGAVRAGHPLSKGTVTPERYAAGRHISVSRRGREKGPIDEALGGLGLRRMVVCMVSGFSAALAMARASELIAS
VPERHTAGARAGMYSFRLPVTTVEVTISMLWHPRLDADPAQRWLRECVREVCASR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=312, Percent_Identity=25.9615384615385, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081684, Length=301, Percent_Identity=25.9136212624585, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081766, Length=174, Percent_Identity=29.3103448275862, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32255; Mature: 32124

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPDLNLLFALDVLLAEGSVARAARRLRLSPSAMSRTLARLREATGDPLLVRAGRGLVA
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEE
TPRAEELRRQVGTVVQDAEALLRPAELLDLSTLDRVFTLRTNEGFVEEFGPCLVARIGAE
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCC
APEVRLRFAPKSDKDVMSLRDAAIDLEIGVAGETGPEVRIQALFRDRFIGAVRAGHPLSK
CCCEEEEECCCCCHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GTVTPERYAAGRHISVSRRGREKGPIDEALGGLGLRRMVVCMVSGFSAALAMARASELIA
CCCCHHHHHCCCEEEHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPERHTAGARAGMYSFRLPVTTVEVTISMLWHPRLDADPAQRWLRECVREVCASR
HCCCHHCCCCCCCCEEEECCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPDLNLLFALDVLLAEGSVARAARRLRLSPSAMSRTLARLREATGDPLLVRAGRGLVA
CCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEE
TPRAEELRRQVGTVVQDAEALLRPAELLDLSTLDRVFTLRTNEGFVEEFGPCLVARIGAE
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCC
APEVRLRFAPKSDKDVMSLRDAAIDLEIGVAGETGPEVRIQALFRDRFIGAVRAGHPLSK
CCCEEEEECCCCCHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GTVTPERYAAGRHISVSRRGREKGPIDEALGGLGLRRMVVCMVSGFSAALAMARASELIA
CCCCHHHHHCCCEEEHHCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVPERHTAGARAGMYSFRLPVTTVEVTISMLWHPRLDADPAQRWLRECVREVCASR
HCCCHHCCCCCCCCEEEECCCEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]