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The map label for this gene is fabZ

Identifier: 13470833

GI number: 13470833

Start: 501134

End: 501592

Strand: Reverse

Name: fabZ

Synonym: mll0634

Alternate gene names: 13470833

Gene position: 501592-501134 (Counterclockwise)

Preceding gene: 13470834

Following gene: 13470832

Centisome position: 7.13

GC content: 59.48

Gene sequence:

>459_bases
ATGGTGGCGGCGACGACGCTGGAAGCGGTCGACATAATGGGGCTGATGAAGCTCCTGCCACACCGCTATCCCTTCCTGAT
GATCGACCGCATCATCGACATCGATGGTGACGATTCCGCCATCGGCATCAAGAACGTCACCATCAACGAGCCGCATTTTC
AGGGGCATTTCCCGGAGCAGCCGGTGATGCCGGGCGTGCTGATCGTCGAAGCCATGGCGCAGACGGCAGGCGCCATCTGC
ATCCGCAGCCTCGGGGCGTCGAAGCCGTCGCTGGTCTATTTCCTGACCATCGACAACGCCAAATTCCGCAAACCGGTCGT
TCCCGGCGACCAGTTGAAGATTCACGTCAAAAAAATCAAGAAGCGCGGCAACCTGCTCAAATTCGCCTGTGAAGCCCTGG
TCGATGGCACCAAGGCGGCCGAGGCCGAGATTTCAGCCATGATGGTCACCGGCGACTGA

Upstream 100 bases:

>100_bases
GGCGGTTATCCGGCACAGCCGATGGCGGAAGCCATGCGGGAGATAGCCATGTTGCGCACGATGGCAAGGGCACGCAAGCA
GGGCAAGGACAATGGCTGAT

Downstream 100 bases:

>100_bases
CGATCGAGTGCTTATGAAAATCAAGACTTCAATCCATCCTTCCTCCGTCGTGGAAGAAGGCGCCCAAATCGGTGAGGGTG
TACGCATTGGGCCGTTCTGC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MVAATTLEAVDIMGLMKLLPHRYPFLMIDRIIDIDGDDSAIGIKNVTINEPHFQGHFPEQPVMPGVLIVEAMAQTAGAIC
IRSLGASKPSLVYFLTIDNAKFRKPVVPGDQLKIHVKKIKKRGNLLKFACEALVDGTKAAEAEISAMMVTGD

Sequences:

>Translated_152_residues
MVAATTLEAVDIMGLMKLLPHRYPFLMIDRIIDIDGDDSAIGIKNVTINEPHFQGHFPEQPVMPGVLIVEAMAQTAGAIC
IRSLGASKPSLVYFLTIDNAKFRKPVVPGDQLKIHVKKIKKRGNLLKFACEALVDGTKAAEAEISAMMVTGD
>Mature_152_residues
MVAATTLEAVDIMGLMKLLPHRYPFLMIDRIIDIDGDDSAIGIKNVTINEPHFQGHFPEQPVMPGVLIVEAMAQTAGAIC
IRSLGASKPSLVYFLTIDNAKFRKPVVPGDQLKIHVKKIKKRGNLLKFACEALVDGTKAAEAEISAMMVTGD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=47.1428571428571, Blast_Score=140, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_RHILO (Q98MC5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102402.1
- ProteinModelPortal:   Q98MC5
- SMR:   Q98MC5
- GeneID:   1225065
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0634
- NMPDR:   fig|266835.1.peg.507
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 16515; Mature: 16515

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: ACT_SITE 56-56

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAATTLEAVDIMGLMKLLPHRYPFLMIDRIIDIDGDDSAIGIKNVTINEPHFQGHFPEQ
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCC
PVMPGVLIVEAMAQTAGAICIRSLGASKPSLVYFLTIDNAKFRKPVVPGDQLKIHVKKIK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHH
KRGNLLKFACEALVDGTKAAEAEISAMMVTGD
HCCCHHHHHHHHHHCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MVAATTLEAVDIMGLMKLLPHRYPFLMIDRIIDIDGDDSAIGIKNVTINEPHFQGHFPEQ
CCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCCCCCCCC
PVMPGVLIVEAMAQTAGAICIRSLGASKPSLVYFLTIDNAKFRKPVVPGDQLKIHVKKIK
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHH
KRGNLLKFACEALVDGTKAAEAEISAMMVTGD
HCCCHHHHHHHHHHCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968