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The map label for this gene is laaA [H]

Identifier: 13470803

GI number: 13470803

Start: 466923

End: 467828

Strand: Reverse

Name: laaA [H]

Synonym: mll0601

Alternate gene names: 13470803

Gene position: 467828-466923 (Counterclockwise)

Preceding gene: 13470804

Following gene: 13470802

Centisome position: 6.65

GC content: 63.13

Gene sequence:

>906_bases
ATGTCGTCAGAGGTCGCTAGCAAAGAGGGACGAGCCCCGTTCGGCAGTTACGAGACCTGGTATCGCATTTCTGGCGATCT
CGATGCCGACAAGGCCCCGGTGGTGGTCCTGCATGGCGGGCCGGGCGCCGCCCACAACTACGTCGATGCCTATAAGCTTC
TCGCCCGACGGGACCGCGCCGTCATCCACTACGACCAGTTGGGCTGCGGCAATTCCACTTTGTTGCCGCAGAAGGGCGCC
GACTTCTGGACGCCACGGCTTTTCATCGACGAGCTTGAAAACCTCGTCGACCATCTCGGCATCCGCGCGGGCTTCCACGT
GCTCGGCCAGAGCTGGGGTGGCATGCTGGGCGCCGAATATGGGGTGACGCGGCCGAAAGGTCTGAAGTCGCTGACCATCG
CCAACTCGCCGGCTTCCATGAAGCTTTGGGTCGAAGAGGCCAACCGGTTGCGCGCCGAGCTGCCCGGGGATGTACAGGAG
ACGCTGACCCGGCACGAGCAGGCCGGCACGACGGACGACCCAGCCTACCAGGCAGCGACGATGGCGTTCTACGAGCGGCA
TGTCTGCCGGGTCGTGCCTTTCCCGCCGGAGGTGACGGAGATCTTCGACCAGATCGCGCGCAATCCGACCGTCTATCACC
TGATGAACGGGCCGAACGAGTTCCATGTCATCGGAACGCTGAAGAACTGGAGCGTCATCGAGCGCTTGCCGGCGGTCGAT
GTTCCCACGTTGATCATCTCCGGACGCTACGACGAGGCCACACCCGCGACCGTGCAGCCCTACAAGGACGGCATCAAGGG
ATCGCGCTGGGAGATATTCGAGCATTCCAGCCACATGCCGCATGTCGAAGAGCAGGACGCGTGCATGCGGGTGGTGGGCG
ACTTTCTGGACGACAACGACAACTGA

Upstream 100 bases:

>100_bases
CGGCGTGCAGATGCTGGAAGAGTGGGTGCAGACCAGGCTGAACTAGACGCCTGCTGTCGGGGACAGAAACGAAATGCGTT
TAAACGTGATGGGAACCGGG

Downstream 100 bases:

>100_bases
GAAAAGGGGAACCAAGACATGAAGAAACTGCTTTTGGCAGCATCCGCCGCGGCACTGCTGGCCGGCACGTGGCTCGCTCC
GGCACAGGCTGAGTATCTCA

Product: proline iminopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSSEVASKEGRAPFGSYETWYRISGDLDADKAPVVVLHGGPGAAHNYVDAYKLLARRDRAVIHYDQLGCGNSTLLPQKGA
DFWTPRLFIDELENLVDHLGIRAGFHVLGQSWGGMLGAEYGVTRPKGLKSLTIANSPASMKLWVEEANRLRAELPGDVQE
TLTRHEQAGTTDDPAYQAATMAFYERHVCRVVPFPPEVTEIFDQIARNPTVYHLMNGPNEFHVIGTLKNWSVIERLPAVD
VPTLIISGRYDEATPATVQPYKDGIKGSRWEIFEHSSHMPHVEEQDACMRVVGDFLDDNDN

Sequences:

>Translated_301_residues
MSSEVASKEGRAPFGSYETWYRISGDLDADKAPVVVLHGGPGAAHNYVDAYKLLARRDRAVIHYDQLGCGNSTLLPQKGA
DFWTPRLFIDELENLVDHLGIRAGFHVLGQSWGGMLGAEYGVTRPKGLKSLTIANSPASMKLWVEEANRLRAELPGDVQE
TLTRHEQAGTTDDPAYQAATMAFYERHVCRVVPFPPEVTEIFDQIARNPTVYHLMNGPNEFHVIGTLKNWSVIERLPAVD
VPTLIISGRYDEATPATVQPYKDGIKGSRWEIFEHSSHMPHVEEQDACMRVVGDFLDDNDN
>Mature_300_residues
SSEVASKEGRAPFGSYETWYRISGDLDADKAPVVVLHGGPGAAHNYVDAYKLLARRDRAVIHYDQLGCGNSTLLPQKGAD
FWTPRLFIDELENLVDHLGIRAGFHVLGQSWGGMLGAEYGVTRPKGLKSLTIANSPASMKLWVEEANRLRAELPGDVQET
LTRHEQAGTTDDPAYQAATMAFYERHVCRVVPFPPEVTEIFDQIARNPTVYHLMNGPNEFHVIGTLKNWSVIERLPAVDV
PTLIISGRYDEATPATVQPYKDGIKGSRWEIFEHSSHMPHVEEQDACMRVVGDFLDDNDN

Specific function: Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L- alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinam

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.5.1.101 [H]

Molecular weight: Translated: 33515; Mature: 33384

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEVASKEGRAPFGSYETWYRISGDLDADKAPVVVLHGGPGAAHNYVDAYKLLARRDRA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCE
VIHYDQLGCGNSTLLPQKGADFWTPRLFIDELENLVDHLGIRAGFHVLGQSWGGMLGAEY
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GVTRPKGLKSLTIANSPASMKLWVEEANRLRAELPGDVQETLTRHEQAGTTDDPAYQAAT
CCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHH
MAFYERHVCRVVPFPPEVTEIFDQIARNPTVYHLMNGPNEFHVIGTLKNWSVIERLPAVD
HHHHHHHHHEEECCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCHHHHHCCCCC
VPTLIISGRYDEATPATVQPYKDGIKGSRWEIFEHSSHMPHVEEQDACMRVVGDFLDDND
CCEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
N
C
>Mature Secondary Structure 
SSEVASKEGRAPFGSYETWYRISGDLDADKAPVVVLHGGPGAAHNYVDAYKLLARRDRA
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCE
VIHYDQLGCGNSTLLPQKGADFWTPRLFIDELENLVDHLGIRAGFHVLGQSWGGMLGAEY
EEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GVTRPKGLKSLTIANSPASMKLWVEEANRLRAELPGDVQETLTRHEQAGTTDDPAYQAAT
CCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHH
MAFYERHVCRVVPFPPEVTEIFDQIARNPTVYHLMNGPNEFHVIGTLKNWSVIERLPAVD
HHHHHHHHHEEECCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCHHHHHCCCCC
VPTLIISGRYDEATPATVQPYKDGIKGSRWEIFEHSSHMPHVEEQDACMRVVGDFLDDND
CCEEEEECCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA