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The map label for this gene is yfdZ [C]

Identifier: 13470488

GI number: 13470488

Start: 142471

End: 143619

Strand: Direct

Name: yfdZ [C]

Synonym: mlr0210

Alternate gene names: 13470488

Gene position: 142471-143619 (Clockwise)

Preceding gene: 13470481

Following gene: 13470489

Centisome position: 2.02

GC content: 64.49

Gene sequence:

>1149_bases
ATGGTCGTTTCGCTCTCGCGTCGTGGCAATGTCGAGCCGTTCCACGCCATGGATGTGCTGGCCGAAGCGAACCGGCTGAA
AGCGCAGGGTGTGCCGGTGATCTCCATGGCGGTCGGCCAACCGTCCGATCCGGCGCCCGTACGGGTCCGAGCCGCCGCGG
CCAGGGCCTTGCAGGACGGTCGCATCGGCTACACCGACACGCTGGGGCTAGCTGGCCTGCGCAAGGCGATCGCCGAGCAC
TACGCGGATCACTATAGGCTGGAAGTCGAGCCCGCCCGGATCGCGGTGACCACCGGATCGTCCGCGGCCTTCAATCTCGC
CTTCTTGGCTATGTTCGATCCGGGCGATCGCGTTGCCATCGCGGCACCCGGCTACCCTGCCTATCGCAACATCATGGCGG
CGCTCGGCATCGATGTGGTCGAGATCGAGCTCGGCGACGCGGCCTATCTGCATGCCGGTCATCTTGAGACCGCGCATCGC
GAGAAACCGCTGAAGGGTGTGCTTTTTGCAAGTCCGGCCAATCCGACCGGTGCCGTCATACCGGCCGACGAACTGTCGGC
GCTGGTCAATACGGCGGAGGCACTGGGGATCGCCGTCATTTCCGACGAAATCTACCACCGGTTGGCCTATGGTGCGCCTG
ACACCACCGCACTTGCCTTCGGCAACAGCGTCACGGTGATCAATTCCTTCTCGAAATACTACTGCATGACCGGTTGGCGC
ATCGGCTGGATGGTGTTGCCGGAAGAGCTGGTGCGGCCCGTCGAGCGCATCGCCCAGAGCCTCTACATTTCGCCGCCGGA
ACTCTCGCAGATCGCCGCGATCGAGGCCTTTGCCGCCACCGAAGAGCTGGAGGCGGTCAAAGGCCGCTATGCCTGGAATC
GCGAACTGCTGATGAAGCGCCTGCCGGAACTCGGCTTTCCGCTGGCCGCGCCCATGGACGGCGCCTTCTATGCGTTTTGC
GATGTCACCCGCCACAGCAATGACAGCATGGCCTTCGCGCGCAAGATGCTGGCCGAGGCGCATGTCGCGGCGACGCCCGG
CCGCGATTTCGACACCCAGGCCGGACATCGCACGATGCGGTTTTCCTACGCCGGCAGCCATGACGACATGGTCGAGGCGA
TGGCGCGCATCGAACGCTGGTTGAGGTAG

Upstream 100 bases:

>100_bases
CGGAAAACTTCCTCAACTTGTGATCCTCACATCAATCGGGCATTTGTGCGGCGCATGTATTCGGGGGCGTGGCGCGCCCA
ACCGTCGGGATAGGGATAAA

Downstream 100 bases:

>100_bases
CGCCATGCCGGAACTCGAACGGGCCCCCAAACTTGATCAAGCATTGGCCGAAGTCGCCGCCGAAATGGCCGAACGCACCG
ATCGCGGCGATGTCGCCACC

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MVVSLSRRGNVEPFHAMDVLAEANRLKAQGVPVISMAVGQPSDPAPVRVRAAAARALQDGRIGYTDTLGLAGLRKAIAEH
YADHYRLEVEPARIAVTTGSSAAFNLAFLAMFDPGDRVAIAAPGYPAYRNIMAALGIDVVEIELGDAAYLHAGHLETAHR
EKPLKGVLFASPANPTGAVIPADELSALVNTAEALGIAVISDEIYHRLAYGAPDTTALAFGNSVTVINSFSKYYCMTGWR
IGWMVLPEELVRPVERIAQSLYISPPELSQIAAIEAFAATEELEAVKGRYAWNRELLMKRLPELGFPLAAPMDGAFYAFC
DVTRHSNDSMAFARKMLAEAHVAATPGRDFDTQAGHRTMRFSYAGSHDDMVEAMARIERWLR

Sequences:

>Translated_382_residues
MVVSLSRRGNVEPFHAMDVLAEANRLKAQGVPVISMAVGQPSDPAPVRVRAAAARALQDGRIGYTDTLGLAGLRKAIAEH
YADHYRLEVEPARIAVTTGSSAAFNLAFLAMFDPGDRVAIAAPGYPAYRNIMAALGIDVVEIELGDAAYLHAGHLETAHR
EKPLKGVLFASPANPTGAVIPADELSALVNTAEALGIAVISDEIYHRLAYGAPDTTALAFGNSVTVINSFSKYYCMTGWR
IGWMVLPEELVRPVERIAQSLYISPPELSQIAAIEAFAATEELEAVKGRYAWNRELLMKRLPELGFPLAAPMDGAFYAFC
DVTRHSNDSMAFARKMLAEAHVAATPGRDFDTQAGHRTMRFSYAGSHDDMVEAMARIERWLR
>Mature_382_residues
MVVSLSRRGNVEPFHAMDVLAEANRLKAQGVPVISMAVGQPSDPAPVRVRAAAARALQDGRIGYTDTLGLAGLRKAIAEH
YADHYRLEVEPARIAVTTGSSAAFNLAFLAMFDPGDRVAIAAPGYPAYRNIMAALGIDVVEIELGDAAYLHAGHLETAHR
EKPLKGVLFASPANPTGAVIPADELSALVNTAEALGIAVISDEIYHRLAYGAPDTTALAFGNSVTVINSFSKYYCMTGWR
IGWMVLPEELVRPVERIAQSLYISPPELSQIAAIEAFAATEELEAVKGRYAWNRELLMKRLPELGFPLAAPMDGAFYAFC
DVTRHSNDSMAFARKMLAEAHVAATPGRDFDTQAGHRTMRFSYAGSHDDMVEAMARIERWLR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=334, Percent_Identity=24.5508982035928, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI169881279, Length=334, Percent_Identity=24.5508982035928, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI56713256, Length=409, Percent_Identity=22.7383863080685, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI56713254, Length=409, Percent_Identity=22.7383863080685, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4507369, Length=225, Percent_Identity=25.3333333333333, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=28.1984334203655, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788627, Length=242, Percent_Identity=28.9256198347107, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1786816, Length=360, Percent_Identity=24.7222222222222, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790797, Length=187, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787710, Length=325, Percent_Identity=24.9230769230769, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994476, Length=411, Percent_Identity=25.0608272506083, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=411, Percent_Identity=25.0608272506083, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=24.0540540540541, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=390, Percent_Identity=22.5641025641026, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=22.6221079691517, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18859735, Length=229, Percent_Identity=27.0742358078603, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=394, Percent_Identity=22.3350253807107, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646114, Length=394, Percent_Identity=22.3350253807107, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573067, Length=394, Percent_Identity=22.3350253807107, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573065, Length=394, Percent_Identity=22.3350253807107, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 41456; Mature: 41456

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVSLSRRGNVEPFHAMDVLAEANRLKAQGVPVISMAVGQPSDPAPVRVRAAAARALQDG
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEHHHHHHHHHCC
RIGYTDTLGLAGLRKAIAEHYADHYRLEVEPARIAVTTGSSAAFNLAFLAMFDPGDRVAI
CCCCCHHHHHHHHHHHHHHHHHHHEEEEEECEEEEEEECCCCEEEEEEEEEECCCCEEEE
AAPGYPAYRNIMAALGIDVVEIELGDAAYLHAGHLETAHREKPLKGVLFASPANPTGAVI
ECCCCHHHHHHHHHHCCEEEEEEECCEEEEECCCCCHHHHCCCCCEEEEECCCCCCCCEE
PADELSALVNTAEALGIAVISDEIYHRLAYGAPDTTALAFGNSVTVINSFSKYYCMTGWR
CHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCCCEEEEECCEEEEEECCCHHEEECCCE
IGWMVLPEELVRPVERIAQSLYISPPELSQIAAIEAFAATEELEAVKGRYAWNRELLMKR
EEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LPELGFPLAAPMDGAFYAFCDVTRHSNDSMAFARKMLAEAHVAATPGRDFDTQAGHRTMR
CHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
FSYAGSHDDMVEAMARIERWLR
EEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVVSLSRRGNVEPFHAMDVLAEANRLKAQGVPVISMAVGQPSDPAPVRVRAAAARALQDG
CEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEHHHHHHHHHCC
RIGYTDTLGLAGLRKAIAEHYADHYRLEVEPARIAVTTGSSAAFNLAFLAMFDPGDRVAI
CCCCCHHHHHHHHHHHHHHHHHHHEEEEEECEEEEEEECCCCEEEEEEEEEECCCCEEEE
AAPGYPAYRNIMAALGIDVVEIELGDAAYLHAGHLETAHREKPLKGVLFASPANPTGAVI
ECCCCHHHHHHHHHHCCEEEEEEECCEEEEECCCCCHHHHCCCCCEEEEECCCCCCCCEE
PADELSALVNTAEALGIAVISDEIYHRLAYGAPDTTALAFGNSVTVINSFSKYYCMTGWR
CHHHHHHHHHHHHHHEEEEEHHHHHHHHHCCCCCCEEEEECCEEEEEECCCHHEEECCCE
IGWMVLPEELVRPVERIAQSLYISPPELSQIAAIEAFAATEELEAVKGRYAWNRELLMKR
EEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LPELGFPLAAPMDGAFYAFCDVTRHSNDSMAFARKMLAEAHVAATPGRDFDTQAGHRTMR
CHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
FSYAGSHDDMVEAMARIERWLR
EEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]