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The map label for this gene is apaH [H]

Identifier: 134302452

GI number: 134302452

Start: 1503025

End: 1503852

Strand: Reverse

Name: apaH [H]

Synonym: FTW_1600

Alternate gene names: 134302452

Gene position: 1503852-1503025 (Counterclockwise)

Preceding gene: 134302453

Following gene: 134302451

Centisome position: 79.21

GC content: 31.04

Gene sequence:

>828_bases
ATGGCTACATATGTTATCGGCGACGTACAGGGCTGTTACGATGAACTGCAATTATTACTACAAAAGATAAATTTTGATAT
ACAAAAAGATAAGCTTATTTTTGCTGGTGATATTATTAATAAAGGTCCAAAATCTCTTGAAACTGTAAACTTTATTATGT
CTTTAGGTGATTCAGCGCAAGTTATCTTAGGGAATCATGAAATATTATTTTTAGCGGTTAGCTATAATTATTTACCTTCA
AATAATAAAAATACCTTTAATGATGTCATTAAAGCGGAAAACCTAAAAGAGATTCAAGACTGGTTGTGTAATCAAAATCT
TTTAATAAGGATTGGCGATGTCTTTATAACTCATGCAGGAATTCCACATATTTGGTCACCTAAGAAAGCAATGAAAAGGG
CTAATGAAGTTGAGTTTGTACTAAAAAATCAAACAACAAGAAGACTTTTACTAGCAAATCTTTTTAGTAATGAGGGTGAT
AAATGGGATAAAGAACTAGAGGGTATTGAAAGATGGTTATGTATCCTTAACTACTTTACACGAATGAGGAGTATTGAGAA
AAATGGTCGTCTGAATCTTAAATTTAGTTCAACTATTGATCAGATACCTGAGAACTTTAAACCATGGTTCAAATTAAAAC
ATAAAAAATTTACAGATAAATATAAGATAATCTTTGGGCATTGGGCAGCTATCAAAGGTGAGACAAAAGATAATAATGTA
ATAGCTTTAGATACAGGATGTGTGTTTGGAGGTAAGCTTACTTGTTATTGCATCGAGACGGAAAAAAAATACGCAGTAAA
AGCACTCAAAAGTTATAAGGATATATAG

Upstream 100 bases:

>100_bases
ATCCTAGCACACTGCCGGTAGATACTAATCTTAGAGCAGAGAATTTAAGTGTTGGAGATTTTGTCAGCTTAGCAAACTTT
TTAAGTTAAGGCATAACAAA

Downstream 100 bases:

>100_bases
AATATGGATGTTTTAGTTATTAACGGACCAAATCTTAACTTATTGGGTACTCGACAACCACAGTTTTATGGTCATAAAAC
TTTAGCTGATATTAACAATG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MATYVIGDVQGCYDELQLLLQKINFDIQKDKLIFAGDIINKGPKSLETVNFIMSLGDSAQVILGNHEILFLAVSYNYLPS
NNKNTFNDVIKAENLKEIQDWLCNQNLLIRIGDVFITHAGIPHIWSPKKAMKRANEVEFVLKNQTTRRLLLANLFSNEGD
KWDKELEGIERWLCILNYFTRMRSIEKNGRLNLKFSSTIDQIPENFKPWFKLKHKKFTDKYKIIFGHWAAIKGETKDNNV
IALDTGCVFGGKLTCYCIETEKKYAVKALKSYKDI

Sequences:

>Translated_275_residues
MATYVIGDVQGCYDELQLLLQKINFDIQKDKLIFAGDIINKGPKSLETVNFIMSLGDSAQVILGNHEILFLAVSYNYLPS
NNKNTFNDVIKAENLKEIQDWLCNQNLLIRIGDVFITHAGIPHIWSPKKAMKRANEVEFVLKNQTTRRLLLANLFSNEGD
KWDKELEGIERWLCILNYFTRMRSIEKNGRLNLKFSSTIDQIPENFKPWFKLKHKKFTDKYKIIFGHWAAIKGETKDNNV
IALDTGCVFGGKLTCYCIETEKKYAVKALKSYKDI
>Mature_274_residues
ATYVIGDVQGCYDELQLLLQKINFDIQKDKLIFAGDIINKGPKSLETVNFIMSLGDSAQVILGNHEILFLAVSYNYLPSN
NKNTFNDVIKAENLKEIQDWLCNQNLLIRIGDVFITHAGIPHIWSPKKAMKRANEVEFVLKNQTTRRLLLANLFSNEGDK
WDKELEGIERWLCILNYFTRMRSIEKNGRLNLKFSSTIDQIPENFKPWFKLKHKKFTDKYKIIFGHWAAIKGETKDNNVI
ALDTGCVFGGKLTCYCIETEKKYAVKALKSYKDI

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=278, Percent_Identity=38.1294964028777, Blast_Score=197, Evalue=9e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31724; Mature: 31593

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYVIGDVQGCYDELQLLLQKINFDIQKDKLIFAGDIINKGPKSLETVNFIMSLGDSAQ
CCEEEEECHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHCCCCHHHHHHHHHHHCCCCCE
VILGNHEILFLAVSYNYLPSNNKNTFNDVIKAENLKEIQDWLCNQNLLIRIGDVFITHAG
EEECCCEEEEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHCCCCEEEEEEEEEEECCC
IPHIWSPKKAMKRANEVEFVLKNQTTRRLLLANLFSNEGDKWDKELEGIERWLCILNYFT
CCCCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RMRSIEKNGRLNLKFSSTIDQIPENFKPWFKLKHKKFTDKYKIIFGHWAAIKGETKDNNV
HHHHHHCCCEEEEEECCHHHHCCCCCCHHHEEHHHCCCCCEEEEEEEEEEEECCCCCCCE
IALDTGCVFGGKLTCYCIETEKKYAVKALKSYKDI
EEEECCEEECCCEEEEEEECCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATYVIGDVQGCYDELQLLLQKINFDIQKDKLIFAGDIINKGPKSLETVNFIMSLGDSAQ
CEEEEECHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHCCCCHHHHHHHHHHHCCCCCE
VILGNHEILFLAVSYNYLPSNNKNTFNDVIKAENLKEIQDWLCNQNLLIRIGDVFITHAG
EEECCCEEEEEEEEEEECCCCCCCHHHHHHHHCCHHHHHHHHCCCCEEEEEEEEEEECCC
IPHIWSPKKAMKRANEVEFVLKNQTTRRLLLANLFSNEGDKWDKELEGIERWLCILNYFT
CCCCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
RMRSIEKNGRLNLKFSSTIDQIPENFKPWFKLKHKKFTDKYKIIFGHWAAIKGETKDNNV
HHHHHHCCCEEEEEECCHHHHCCCCCCHHHEEHHHCCCCCEEEEEEEEEEEECCCCCCCE
IALDTGCVFGGKLTCYCIETEKKYAVKALKSYKDI
EEEECCEEECCCEEEEEEECCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA