Click here to switch to the map view.

The map label for this gene is yugH [H]

Identifier: 134302223

GI number: 134302223

Start: 1228409

End: 1229599

Strand: Direct

Name: yugH [H]

Synonym: FTW_1295

Alternate gene names: 134302223

Gene position: 1228409-1229599 (Clockwise)

Preceding gene: 134302220

Following gene: 134302225

Centisome position: 64.71

GC content: 36.69

Gene sequence:

>1191_bases
ATGCAATTATCAAGAAGAGTAAAGGCAATGCAAGCCTCTCCAGTACGTAAGTTAGTGCCGTATTCTATTCAAGCAGAAAA
ACAAGGTAAAAAGGTATACCACCTTAATATTGGTCAGCCTGATATCAAAACTCCTAATGAGTTTATGGATGCTATCAGAG
CTTATGACAAAGAGACTATCGCCTACTCTATAGCAAGTGGTGAGCCAAGCTTAATCAAAGCTATATCAAAATACTACAAA
AGATTTGATATGGACTTTGCTGAGGATGAAATCTTAATCACTAACGGTGGTTCTGAAGCGCTAATATTTGCTGCGATTGC
TACTTGTAATGCTGGTGATGAGATACTTGTACCAGAACCTTTCTATACAAACTATAATGGCTTCACAACTGCTGTTGATG
TGTCTATAAGACCAATCACAACAAAAGCTGAAGAAGGTTTCCATTTACCTTCAAAAGAAGAGATCCTAGCATGTGTAACT
GATAAAACTCGTGCTATCATGATTTCTAACCCTGGTAACCCTACTGGTGTTGTATATACAAAACAAGAGCTAGAAACTTT
AGCAGAAGTTGCTAAAGAAAAAGATCTATTTATTATCAGTGATGAGGTATATAGAGAGTTTACTTATGATGGGCTTGTAT
GTACATCTTTTGGCAATATCAAAGGTGTCGAAGATCGTGTGATTATCGTTGACTCGGTATCTAAGCGCTATAGTGCTTGT
GGTGCTAGAATTGGCTCTCTTTGTTCAAAAAATAAAGAGTTTATCAAGGAAGCTACTAAACTATGCCAAGCTAGATTATG
TGTGCCAACTCTTGAGCAAATCGGTGCTGCGGCTCTTTATGAAGTATCAGAAGATTACCTAAAAGAAGTAAATACAGAAT
ACCAAAAAAGAAGAGATATCACTTTCGAAGCTCTTTCAAAAATGGATAATGTAGTTTGTGAAAAGCCTACTGGTGCTTTC
TATGTAATCGCGAAACTACCTATCGATGATGCTGAGAAATTTGCACTATGGTTACTAACAGACTTTGAAGATAATCGCGA
AACTGTGATGATCTCTCCTGCTGGTGATTTCTATGCAACCAAAGGTCTAGGTAAAGATGAGATAAGAATCGCATATATCT
TAGAAGAGAAATCACTAAGAAGAGCTCTAGAGCTCTTAGATAAAGCTATCAAAGCTTATAACAGTAAATAA

Upstream 100 bases:

>100_bases
TAAAATATCAATAAATTAAATATTCTTTCCATAATAAAAATATATTATAATCGCTTGTGGTCTATTTGACTAATATCAAA
AACATAGAAGGATTTATTAG

Downstream 100 bases:

>100_bases
GAATACTTTATATTTCCTTTATAAATCTTCTAAATTACCTTAGAAAATCTAAAAAGTAACAACTGTTCTAATATTATTGT
GCATATCAGCAAAACCTTTA

Product: aspartate aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MQLSRRVKAMQASPVRKLVPYSIQAEKQGKKVYHLNIGQPDIKTPNEFMDAIRAYDKETIAYSIASGEPSLIKAISKYYK
RFDMDFAEDEILITNGGSEALIFAAIATCNAGDEILVPEPFYTNYNGFTTAVDVSIRPITTKAEEGFHLPSKEEILACVT
DKTRAIMISNPGNPTGVVYTKQELETLAEVAKEKDLFIISDEVYREFTYDGLVCTSFGNIKGVEDRVIIVDSVSKRYSAC
GARIGSLCSKNKEFIKEATKLCQARLCVPTLEQIGAAALYEVSEDYLKEVNTEYQKRRDITFEALSKMDNVVCEKPTGAF
YVIAKLPIDDAEKFALWLLTDFEDNRETVMISPAGDFYATKGLGKDEIRIAYILEEKSLRRALELLDKAIKAYNSK

Sequences:

>Translated_396_residues
MQLSRRVKAMQASPVRKLVPYSIQAEKQGKKVYHLNIGQPDIKTPNEFMDAIRAYDKETIAYSIASGEPSLIKAISKYYK
RFDMDFAEDEILITNGGSEALIFAAIATCNAGDEILVPEPFYTNYNGFTTAVDVSIRPITTKAEEGFHLPSKEEILACVT
DKTRAIMISNPGNPTGVVYTKQELETLAEVAKEKDLFIISDEVYREFTYDGLVCTSFGNIKGVEDRVIIVDSVSKRYSAC
GARIGSLCSKNKEFIKEATKLCQARLCVPTLEQIGAAALYEVSEDYLKEVNTEYQKRRDITFEALSKMDNVVCEKPTGAF
YVIAKLPIDDAEKFALWLLTDFEDNRETVMISPAGDFYATKGLGKDEIRIAYILEEKSLRRALELLDKAIKAYNSK
>Mature_396_residues
MQLSRRVKAMQASPVRKLVPYSIQAEKQGKKVYHLNIGQPDIKTPNEFMDAIRAYDKETIAYSIASGEPSLIKAISKYYK
RFDMDFAEDEILITNGGSEALIFAAIATCNAGDEILVPEPFYTNYNGFTTAVDVSIRPITTKAEEGFHLPSKEEILACVT
DKTRAIMISNPGNPTGVVYTKQELETLAEVAKEKDLFIISDEVYREFTYDGLVCTSFGNIKGVEDRVIIVDSVSKRYSAC
GARIGSLCSKNKEFIKEATKLCQARLCVPTLEQIGAAALYEVSEDYLKEVNTEYQKRRDITFEALSKMDNVVCEKPTGAF
YVIAKLPIDDAEKFALWLLTDFEDNRETVMISPAGDFYATKGLGKDEIRIAYILEEKSLRRALELLDKAIKAYNSK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=424, Percent_Identity=24.2924528301887, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI169881279, Length=424, Percent_Identity=24.2924528301887, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI56713254, Length=337, Percent_Identity=27.5964391691395, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI56713256, Length=337, Percent_Identity=27.5964391691395, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169881281, Length=307, Percent_Identity=24.1042345276873, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4507369, Length=337, Percent_Identity=21.9584569732938, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI149944424, Length=236, Percent_Identity=25.4237288135593, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4885351, Length=237, Percent_Identity=26.5822784810127, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788627, Length=342, Percent_Identity=31.2865497076023, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788722, Length=384, Percent_Identity=26.3020833333333, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1786816, Length=328, Percent_Identity=24.6951219512195, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790797, Length=370, Percent_Identity=22.1621621621622, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=333, Percent_Identity=28.2282282282282, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=400, Percent_Identity=27.25, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=400, Percent_Identity=26.75, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=332, Percent_Identity=27.710843373494, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71981209, Length=324, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=410, Percent_Identity=26.5853658536585, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320317, Length=298, Percent_Identity=23.8255033557047, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=303, Percent_Identity=26.4026402640264, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=26.9922879177378, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=26.9922879177378, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=26.9922879177378, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=26.9922879177378, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI18859735, Length=386, Percent_Identity=22.7979274611399, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641770, Length=303, Percent_Identity=25.4125412541254, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641760, Length=303, Percent_Identity=25.4125412541254, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641768, Length=303, Percent_Identity=25.4125412541254, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641766, Length=303, Percent_Identity=25.4125412541254, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641764, Length=303, Percent_Identity=25.4125412541254, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551451, Length=303, Percent_Identity=25.4125412541254, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 44357; Mature: 44357

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSRRVKAMQASPVRKLVPYSIQAEKQGKKVYHLNIGQPDIKTPNEFMDAIRAYDKETI
CCHHHHHHHHHCCCHHHHCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEE
AYSIASGEPSLIKAISKYYKRFDMDFAEDEILITNGGSEALIFAAIATCNAGDEILVPEP
EEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCEEECCCC
FYTNYNGFTTAVDVSIRPITTKAEEGFHLPSKEEILACVTDKTRAIMISNPGNPTGVVYT
CCCCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHEEEEEECCCEEEEEECCCCCCEEEEE
KQELETLAEVAKEKDLFIISDEVYREFTYDGLVCTSFGNIKGVEDRVIIVDSVSKRYSAC
HHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECHHHHHHHH
GARIGSLCSKNKEFIKEATKLCQARLCVPTLEQIGAAALYEVSEDYLKEVNTEYQKRRDI
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHCC
TFEALSKMDNVVCEKPTGAFYVIAKLPIDDAEKFALWLLTDFEDNRETVMISPAGDFYAT
HHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEE
KGLGKDEIRIAYILEEKSLRRALELLDKAIKAYNSK
CCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLSRRVKAMQASPVRKLVPYSIQAEKQGKKVYHLNIGQPDIKTPNEFMDAIRAYDKETI
CCHHHHHHHHHCCCHHHHCCCCEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEE
AYSIASGEPSLIKAISKYYKRFDMDFAEDEILITNGGSEALIFAAIATCNAGDEILVPEP
EEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEEEEECCCCCEEECCCC
FYTNYNGFTTAVDVSIRPITTKAEEGFHLPSKEEILACVTDKTRAIMISNPGNPTGVVYT
CCCCCCCEEEEEEEEEEEEEECCCCCCCCCCHHHEEEEEECCCEEEEEECCCCCCEEEEE
KQELETLAEVAKEKDLFIISDEVYREFTYDGLVCTSFGNIKGVEDRVIIVDSVSKRYSAC
HHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECHHHHHHHH
GARIGSLCSKNKEFIKEATKLCQARLCVPTLEQIGAAALYEVSEDYLKEVNTEYQKRRDI
HHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHCC
TFEALSKMDNVVCEKPTGAFYVIAKLPIDDAEKFALWLLTDFEDNRETVMISPAGDFYAT
HHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCEE
KGLGKDEIRIAYILEEKSLRRALELLDKAIKAYNSK
CCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]