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The map label for this gene is pilA [H]

Identifier: 134302219

GI number: 134302219

Start: 1222402

End: 1222809

Strand: Direct

Name: pilA [H]

Synonym: FTW_1289

Alternate gene names: 134302219

Gene position: 1222402-1222809 (Clockwise)

Preceding gene: 134302211

Following gene: 134302220

Centisome position: 64.39

GC content: 40.93

Gene sequence:

>408_bases
ATGAAAAAGAAAATGCAAAAAGGTTTCTCACTAGTTGAGTTAATGGTAGTGATCGCGATCATCGCTATCCTAGCAGCTGT
AGCGATCCCGATGTACTCTAACTACACTACACGTGCTCAGTTAGGCTCTGATCTATCTGCTCTAGGTGGTGCTAAAGCTA
CAGTAGCTGAAAGAATAGCTAACAACAATGGTGATGCATCTCAAGTTACAATTCTTCAAGCTAATGCCGCTGCAAATGGT
CTTCCAAGTGGTGCTTCAGTTGCTGCTGGTACTATTAGTTATCCATCAACAGTATCTGGTGCAACAATTCAATTAGCTCC
TACAGTAAGTTCCGGTGCTATTACTTGGACTTGTAATATTTCAGGTGTATCAGCATCTCAAGTACCATCTAACTGTAATG
CTATCTAA

Upstream 100 bases:

>100_bases
ATGATACATTTTAAACAATATAATAAATGGCATATGGTAGAGATTGTTTCTTATCATATTATTAGAATGTAAACTAAACT
ATAAAGAAGGAAAACAAATC

Downstream 100 bases:

>100_bases
TCAATAACAATCAGTAGATAAACTAAGCCACTTTCATGTGGCTTTTTTATATCCAAAATTTTATCTTAATTTCTTTTTTG
ACTTTTTTTAGCTATAATTT

Product: type IV pilus assembly protein

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MKKKMQKGFSLVELMVVIAIIAILAAVAIPMYSNYTTRAQLGSDLSALGGAKATVAERIANNNGDASQVTILQANAAANG
LPSGASVAAGTISYPSTVSGATIQLAPTVSSGAITWTCNISGVSASQVPSNCNAI

Sequences:

>Translated_135_residues
MKKKMQKGFSLVELMVVIAIIAILAAVAIPMYSNYTTRAQLGSDLSALGGAKATVAERIANNNGDASQVTILQANAAANG
LPSGASVAAGTISYPSTVSGATIQLAPTVSSGAITWTCNISGVSASQVPSNCNAI
>Mature_135_residues
MKKKMQKGFSLVELMVVIAIIAILAAVAIPMYSNYTTRAQLGSDLSALGGAKATVAERIANNNGDASQVTILQANAAANG
LPSGASVAAGTISYPSTVSGATIQLAPTVSSGAITWTCNISGVSASQVPSNCNAI

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=136, Percent_Identity=35.2941176470588, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 13500; Mature: 13500

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKMQKGFSLVELMVVIAIIAILAAVAIPMYSNYTTRAQLGSDLSALGGAKATVAERIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCHHHHHHHHH
NNNGDASQVTILQANAAANGLPSGASVAAGTISYPSTVSGATIQLAPTVSSGAITWTCNI
CCCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCEEEEEEEC
SGVSASQVPSNCNAI
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKKMQKGFSLVELMVVIAIIAILAAVAIPMYSNYTTRAQLGSDLSALGGAKATVAERIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHCCCHHHHHHHHH
NNNGDASQVTILQANAAANGLPSGASVAAGTISYPSTVSGATIQLAPTVSSGAITWTCNI
CCCCCCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCCCCEEEEECCCCCCEEEEEEEC
SGVSASQVPSNCNAI
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]