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The map label for this gene is fucA [H]

Identifier: 134299908

GI number: 134299908

Start: 2258353

End: 2259012

Strand: Reverse

Name: fucA [H]

Synonym: Dred_2062

Alternate gene names: 134299908

Gene position: 2259012-2258353 (Counterclockwise)

Preceding gene: 134299909

Following gene: 134299907

Centisome position: 62.61

GC content: 50.15

Gene sequence:

>660_bases
ATGGTAAAGGCAACTGAAAAAGTAAGAGAAACGGTGGCCCGGCTGGGGAGAAAAATGTTGGAGTCTGGTTTGGTTGCAGG
AACCTGGGGAAATATTTCCTGCCGGTTAGAGGCAGAGAATGTTGTGGTTATTACCCCCAGTGGTATGGATTATGCTAATC
TGCAGCCTTCTGATATGGTTGTACTGGATCTAGACGGTCGGGTTATCGAAGGGTACCGAAAGCCATCCAGCGAGGCACCC
CTGCACCTTGCAATTTATCGAGCCAGAAAAGATGTGTTGGGGATTGTACATACTCACAGTGAAGTGGCAACAGCCTTTGG
AGTTTTAAGGGAGCCCATAGAACCCGTGGTAGAAGATGCAGCAATGCTAGTTGGCGGTCCTGTGGAAGTGGCCCGGTATG
CTTTGCCGGGGACAGAAGAACTGGCTCAAAATGTAGTTAAAGCCCTTGGTGAACGCTATGCGGTACTGATGGCGAATCAC
GGGCTAGTGGGTGTTGGCCGAAGGGTTGAAGAAGCGTTTACGGTGTGTCAAGTGGTGGAAAAGTGCGCAAGGATCTATGC
TTGGGCTAAATCCCTGGGCAAACCTGTCGTTATACCGGACCAAGATGTGTCCGAGCTATCTAGGATTTACCGTAGCTCTT
ATGGCCAGCCCCAAAAATAG

Upstream 100 bases:

>100_bases
CTAAAACTAAAATCTTTGGGAGTGGATATTGATTCCCTCACGCCTGAGCAAGAAGCCTATATTAACGAGTGGAACCATGG
TACCTAAGCAGGAGTTAGTA

Downstream 100 bases:

>100_bases
AGAGCACCCCCAAAAGGGGAGCAGTTTTAGGAGAGATGAATTTTGAATAGACTACTTATCCGCGGGGCAACAATTCTAAC
CATGGAAGGTCCAGAAGCCA

Product: class II aldolase/adducin family protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MVKATEKVRETVARLGRKMLESGLVAGTWGNISCRLEAENVVVITPSGMDYANLQPSDMVVLDLDGRVIEGYRKPSSEAP
LHLAIYRARKDVLGIVHTHSEVATAFGVLREPIEPVVEDAAMLVGGPVEVARYALPGTEELAQNVVKALGERYAVLMANH
GLVGVGRRVEEAFTVCQVVEKCARIYAWAKSLGKPVVIPDQDVSELSRIYRSSYGQPQK

Sequences:

>Translated_219_residues
MVKATEKVRETVARLGRKMLESGLVAGTWGNISCRLEAENVVVITPSGMDYANLQPSDMVVLDLDGRVIEGYRKPSSEAP
LHLAIYRARKDVLGIVHTHSEVATAFGVLREPIEPVVEDAAMLVGGPVEVARYALPGTEELAQNVVKALGERYAVLMANH
GLVGVGRRVEEAFTVCQVVEKCARIYAWAKSLGKPVVIPDQDVSELSRIYRSSYGQPQK
>Mature_219_residues
MVKATEKVRETVARLGRKMLESGLVAGTWGNISCRLEAENVVVITPSGMDYANLQPSDMVVLDLDGRVIEGYRKPSSEAP
LHLAIYRARKDVLGIVHTHSEVATAFGVLREPIEPVVEDAAMLVGGPVEVARYALPGTEELAQNVVKALGERYAVLMANH
GLVGVGRRVEEAFTVCQVVEKCARIYAWAKSLGKPVVIPDQDVSELSRIYRSSYGQPQK

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=210, Percent_Identity=32.3809523809524, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1789094, Length=190, Percent_Identity=30.5263157894737, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790642, Length=194, Percent_Identity=31.4432989690722, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786247, Length=224, Percent_Identity=29.9107142857143, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790008, Length=183, Percent_Identity=32.7868852459016, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23884; Mature: 23884

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKATEKVRETVARLGRKMLESGLVAGTWGNISCRLEAENVVVITPSGMDYANLQPSDMV
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCEEEECCCCCCCCCCCCCCEE
VLDLDGRVIEGYRKPSSEAPLHLAIYRARKDVLGIVHTHSEVATAFGVLREPIEPVVEDA
EEECCCCEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVGGPVEVARYALPGTEELAQNVVKALGERYAVLMANHGLVGVGRRVEEAFTVCQVVE
HHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHH
KCARIYAWAKSLGKPVVIPDQDVSELSRIYRSSYGQPQK
HHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVKATEKVRETVARLGRKMLESGLVAGTWGNISCRLEAENVVVITPSGMDYANLQPSDMV
CCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCEEEECCCCCCCCCCCCCCEE
VLDLDGRVIEGYRKPSSEAPLHLAIYRARKDVLGIVHTHSEVATAFGVLREPIEPVVEDA
EEECCCCEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLVGGPVEVARYALPGTEELAQNVVKALGERYAVLMANHGLVGVGRRVEEAFTVCQVVE
HHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHH
KCARIYAWAKSLGKPVVIPDQDVSELSRIYRSSYGQPQK
HHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]