Click here to switch to the map view.

The map label for this gene is dapG [H]

Identifier: 134299788

GI number: 134299788

Start: 2131440

End: 2132666

Strand: Reverse

Name: dapG [H]

Synonym: Dred_1940

Alternate gene names: 134299788

Gene position: 2132666-2131440 (Counterclockwise)

Preceding gene: 134299789

Following gene: 134299787

Centisome position: 59.11

GC content: 43.11

Gene sequence:

>1227_bases
ATGCGTTTTATTATCCAAAAATTTGGTGGAACTTCTCTGGTTACCCAGGAACTTAGGGAGCTAGTAGCAAACAAAATTAT
TGCTGCTGTAGATGAGGGGTTTTCACCGGTTGTTGTGGTATCTGCCATTGGTCGAGCGGGTGAACCCTATGCCACAGATA
CGTTACTCAATTTTGCATTATCCATAAACCGTGACATTCCACCCAGAGAAATGGATATGTTAATGTCCTGTGGTGAGATT
ATATCTGGGGTAGCAATGGCTAATACACTCCAGCGCATGGGACATCAGGCAGTTTTATTAACAGGGGCTCAAGCGGGTAT
CATAACAGATGATAATTTCAATGATGCACGGATTATTCGAGTTGAGCCTCAAAATGTTATTAAGCATGTGGAACAAGGGA
AAATTGTTATAGTAACAGGGTTTCAAGGCATCTGTCAAGGTGGCGACATAACGACCCTAGGCCGCGGTGGCAGTGATACC
ACAGCATCTGCATTGGGAGTAGCCCTCAATGCAGAGTATATTGATATCTATACAGATGTGGAAGGTATTATGACAGCGGA
CCCCCGGATTGTGGAGGACGCAAGGATTTTAGATTCAGTAACTTATAATGAAATATGCCAGCTGGCCCATGAAGGAGCAA
AGGTTATTCACCCTAGGGCAGTGGAAATAGCAATGCAAAAAAATATCCCTCTTCGTGTTCGATCTACCTTTTTGGATTCC
CCAGGAACCCTGGTGACCAGTCATCATGGAGTTTATGGAACCATAGATATTACAAGGGATCGATTGGCATGTGGTGTTAC
CCATATTGCAGGGGTTACACAGTTAAAAATAATTGCCAAGGATATTGCAGTGGAAGATCCAGCATTGCGAATATTCCGGG
CACTGGCCTTAGCAGATATCAGTATAGATTTTATTAATGTCAGTCCAGAGTTAATAATGTTAACAGTGAAGGATGAAGTT
GCAAAGAAGGCTGTTGATGTATTGGAAAATCTAAGTGTTTTTCCGCAAGTGAAACCAAATTGTGCCAAAGTATCTACGGT
TGGCGCAGGGATGACGGGGGTTCCTGGTGTTATGGCCAGCATTATTCAGGCATTGACAGAAGAAGGGGTTGAAATACTGC
AGTCCTCCGACTCCCATACAACAATCTGGGTCTTAGTTGAAAAGGAAAACATGAAGAAAGCCATACGTGCCTTGCATCGA
AAGTTTAAGTTAGGTCAAAGGGAATAA

Upstream 100 bases:

>100_bases
GGGTGGTGGGTGACCAGATTCGCAAGGGTGCGGCCACCAACGCCGTTCAAATTGCTGAATTAGTGCTAAAATATGACAGC
TTAATGAAGAAGGAGTAAAT

Downstream 100 bases:

>100_bases
GGTTATTGAGGGGATGTGAAAGTCAATGTCAACAGTGGATTTTGGCAGGGTTATTACGGCCATGGTGACACCTTTTCATC
CAGATATGTCCGTGAATTAT

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MRFIIQKFGGTSLVTQELRELVANKIIAAVDEGFSPVVVVSAIGRAGEPYATDTLLNFALSINRDIPPREMDMLMSCGEI
ISGVAMANTLQRMGHQAVLLTGAQAGIITDDNFNDARIIRVEPQNVIKHVEQGKIVIVTGFQGICQGGDITTLGRGGSDT
TASALGVALNAEYIDIYTDVEGIMTADPRIVEDARILDSVTYNEICQLAHEGAKVIHPRAVEIAMQKNIPLRVRSTFLDS
PGTLVTSHHGVYGTIDITRDRLACGVTHIAGVTQLKIIAKDIAVEDPALRIFRALALADISIDFINVSPELIMLTVKDEV
AKKAVDVLENLSVFPQVKPNCAKVSTVGAGMTGVPGVMASIIQALTEEGVEILQSSDSHTTIWVLVEKENMKKAIRALHR
KFKLGQRE

Sequences:

>Translated_408_residues
MRFIIQKFGGTSLVTQELRELVANKIIAAVDEGFSPVVVVSAIGRAGEPYATDTLLNFALSINRDIPPREMDMLMSCGEI
ISGVAMANTLQRMGHQAVLLTGAQAGIITDDNFNDARIIRVEPQNVIKHVEQGKIVIVTGFQGICQGGDITTLGRGGSDT
TASALGVALNAEYIDIYTDVEGIMTADPRIVEDARILDSVTYNEICQLAHEGAKVIHPRAVEIAMQKNIPLRVRSTFLDS
PGTLVTSHHGVYGTIDITRDRLACGVTHIAGVTQLKIIAKDIAVEDPALRIFRALALADISIDFINVSPELIMLTVKDEV
AKKAVDVLENLSVFPQVKPNCAKVSTVGAGMTGVPGVMASIIQALTEEGVEILQSSDSHTTIWVLVEKENMKKAIRALHR
KFKLGQRE
>Mature_408_residues
MRFIIQKFGGTSLVTQELRELVANKIIAAVDEGFSPVVVVSAIGRAGEPYATDTLLNFALSINRDIPPREMDMLMSCGEI
ISGVAMANTLQRMGHQAVLLTGAQAGIITDDNFNDARIIRVEPQNVIKHVEQGKIVIVTGFQGICQGGDITTLGRGGSDT
TASALGVALNAEYIDIYTDVEGIMTADPRIVEDARILDSVTYNEICQLAHEGAKVIHPRAVEIAMQKNIPLRVRSTFLDS
PGTLVTSHHGVYGTIDITRDRLACGVTHIAGVTQLKIIAKDIAVEDPALRIFRALALADISIDFINVSPELIMLTVKDEV
AKKAVDVLENLSVFPQVKPNCAKVSTVGAGMTGVPGVMASIIQALTEEGVEILQSSDSHTTIWVLVEKENMKKAIRALHR
KFKLGQRE

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=358, Percent_Identity=27.0949720670391, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790455, Length=356, Percent_Identity=27.8089887640449, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790376, Length=342, Percent_Identity=25.4385964912281, Blast_Score=86, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320893, Length=385, Percent_Identity=25.4545454545455, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44042; Mature: 44042

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFIIQKFGGTSLVTQELRELVANKIIAAVDEGFSPVVVVSAIGRAGEPYATDTLLNFAL
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
SINRDIPPREMDMLMSCGEIISGVAMANTLQRMGHQAVLLTGAQAGIITDDNFNDARIIR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCEEEEE
VEPQNVIKHVEQGKIVIVTGFQGICQGGDITTLGRGGSDTTASALGVALNAEYIDIYTDV
ECHHHHHHHHHCCCEEEEECCHHHCCCCCEEEECCCCCCCHHHHHHEEECCEEEEEEECC
EGIMTADPRIVEDARILDSVTYNEICQLAHEGAKVIHPRAVEIAMQKNIPLRVRSTFLDS
CCEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCEECCHHEEEEECCCCCEEEEHHHCCC
PGTLVTSHHGVYGTIDITRDRLACGVTHIAGVTQLKIIAKDIAVEDPALRIFRALALADI
CCCEEEECCCEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
SIDFINVSPELIMLTVKDEVAKKAVDVLENLSVFPQVKPNCAKVSTVGAGMTGVPGVMAS
EEEEEECCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHH
IIQALTEEGVEILQSSDSHTTIWVLVEKENMKKAIRALHRKFKLGQRE
HHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRFIIQKFGGTSLVTQELRELVANKIIAAVDEGFSPVVVVSAIGRAGEPYATDTLLNFAL
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
SINRDIPPREMDMLMSCGEIISGVAMANTLQRMGHQAVLLTGAQAGIITDDNFNDARIIR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCEEEEE
VEPQNVIKHVEQGKIVIVTGFQGICQGGDITTLGRGGSDTTASALGVALNAEYIDIYTDV
ECHHHHHHHHHCCCEEEEECCHHHCCCCCEEEECCCCCCCHHHHHHEEECCEEEEEEECC
EGIMTADPRIVEDARILDSVTYNEICQLAHEGAKVIHPRAVEIAMQKNIPLRVRSTFLDS
CCEEECCCCHHHHHHHHHHCCHHHHHHHHHCCCCEECCHHEEEEECCCCCEEEEHHHCCC
PGTLVTSHHGVYGTIDITRDRLACGVTHIAGVTQLKIIAKDIAVEDPALRIFRALALADI
CCCEEEECCCEEEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
SIDFINVSPELIMLTVKDEVAKKAVDVLENLSVFPQVKPNCAKVSTVGAGMTGVPGVMAS
EEEEEECCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCHHHHHH
IIQALTEEGVEILQSSDSHTTIWVLVEKENMKKAIRALHRKFKLGQRE
HHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]