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The map label for this gene is selU [H]

Identifier: 134299782

GI number: 134299782

Start: 2122621

End: 2123748

Strand: Reverse

Name: selU [H]

Synonym: Dred_1933

Alternate gene names: 134299782

Gene position: 2123748-2122621 (Counterclockwise)

Preceding gene: 134299783

Following gene: 134299781

Centisome position: 58.86

GC content: 37.23

Gene sequence:

>1128_bases
ATGCTAAAAGATATTTTCATTAATCAAGCTTTACAACAAAATGATGCTTGTTTTATTGATTTACGGTCAGAGGGAGAATT
TGCAGAAGGTTCGATTCCTGGTGCAATAAACATTCCTTTATTTACAAATGAAGAAAGGGCAAAGGTTGGCATAGTATACA
AACAGGTTGGGACGGAAGCCGCCAAAAGATTGGGTTTAGAAATTGCAAGCCCAAAACTTCCGGCACTATATGATGATATT
TCAAAATTGGCTAAGGATAAAACGGTTTTTCTTTACTGTTGGCGTGGAGGAATGCGTAGCAAATATGCAGCCTCGATCTT
AAATACCCTAGGCATAAACCTTTATCGGATACAGGGTGGTTATAAAGCTTATCGTAAGCATATACATGCTTATTTAGATC
AGGACTTGATACCGCATAAATGCATTGTTTTACATGGTTTAACCGGAGTAGGGAAAACCATTGTTTTAAATAACTTAAAT
AGGTTTGGCATACCTGTTTTAGATTTAGAATCTATTGCCTGTCATAGAGGATCAGCCTATGGTAAGATTGGTTTGCCAGA
ATCACCTTCCCAAAAGGATTTTGAGTCAAGTATTGTACAAACCCTTATAAGAGCAGAAGATAAAGGAATGGTAGCTGTAG
AGTGTGAAAGTCGCAGAGTGGGTAAACTAATCGTACCAACTTCAGTTTTCAACGCCATGTCACAGGGTTATCGAGTTTTA
ATGTATGCTTCAATAGAGAAGCGGGTGCAAAGGATTATAGATGAATATACAAAGGGCCCTGATAATAATATTGAAATGCT
GAAGTTAAGTACAGCCCTATTAAAGAAGTCTCTTGGAAACAAAACTGTAGAAGAATTAAATCAAAAGATCGATGAAAGAA
AGTTTGAGGAGGTTATTCCTTACCTTTTAACAAAGTATTACGATCCTCTATATAAATATCCTGATTCACCCAACGATGAA
TATGATTTATCTGTTGATTGTGATGATTTAAATGAAGCCACAGGTATAATTGCGAATTGGGTAACATCTTTACCCGAGTA
TGGTATACCAGCGAAAATCGGAGGTGACGATGGTGGCAGTAGGGGAAGCTTTAAGGAGCGCAAGAAAAGAAAAGGGTTAC
TCGTTTGA

Upstream 100 bases:

>100_bases
TTAGATAGGAAATCCTAAAGTCATAGGGTTTTTTATCTAATTCTTTTTGCAGGATAAAAAAAGAAAAACTAGAATAGATG
CGACAAGGAAGTAAGACAAT

Downstream 100 bases:

>100_bases
ATACTTAGAAGAGGCAACCAAGATTAGAGCGAAATATCTTGAAGCCTTAGAAAATGAAGAATTTGATATTTTGCCTGGGC
CTGTGTATGCAAAGGCCTTC

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLKDIFINQALQQNDACFIDLRSEGEFAEGSIPGAINIPLFTNEERAKVGIVYKQVGTEAAKRLGLEIASPKLPALYDDI
SKLAKDKTVFLYCWRGGMRSKYAASILNTLGINLYRIQGGYKAYRKHIHAYLDQDLIPHKCIVLHGLTGVGKTIVLNNLN
RFGIPVLDLESIACHRGSAYGKIGLPESPSQKDFESSIVQTLIRAEDKGMVAVECESRRVGKLIVPTSVFNAMSQGYRVL
MYASIEKRVQRIIDEYTKGPDNNIEMLKLSTALLKKSLGNKTVEELNQKIDERKFEEVIPYLLTKYYDPLYKYPDSPNDE
YDLSVDCDDLNEATGIIANWVTSLPEYGIPAKIGGDDGGSRGSFKERKKRKGLLV

Sequences:

>Translated_375_residues
MLKDIFINQALQQNDACFIDLRSEGEFAEGSIPGAINIPLFTNEERAKVGIVYKQVGTEAAKRLGLEIASPKLPALYDDI
SKLAKDKTVFLYCWRGGMRSKYAASILNTLGINLYRIQGGYKAYRKHIHAYLDQDLIPHKCIVLHGLTGVGKTIVLNNLN
RFGIPVLDLESIACHRGSAYGKIGLPESPSQKDFESSIVQTLIRAEDKGMVAVECESRRVGKLIVPTSVFNAMSQGYRVL
MYASIEKRVQRIIDEYTKGPDNNIEMLKLSTALLKKSLGNKTVEELNQKIDERKFEEVIPYLLTKYYDPLYKYPDSPNDE
YDLSVDCDDLNEATGIIANWVTSLPEYGIPAKIGGDDGGSRGSFKERKKRKGLLV
>Mature_375_residues
MLKDIFINQALQQNDACFIDLRSEGEFAEGSIPGAINIPLFTNEERAKVGIVYKQVGTEAAKRLGLEIASPKLPALYDDI
SKLAKDKTVFLYCWRGGMRSKYAASILNTLGINLYRIQGGYKAYRKHIHAYLDQDLIPHKCIVLHGLTGVGKTIVLNNLN
RFGIPVLDLESIACHRGSAYGKIGLPESPSQKDFESSIVQTLIRAEDKGMVAVECESRRVGKLIVPTSVFNAMSQGYRVL
MYASIEKRVQRIIDEYTKGPDNNIEMLKLSTALLKKSLGNKTVEELNQKIDERKFEEVIPYLLTKYYDPLYKYPDSPNDE
YDLSVDCDDLNEATGIIANWVTSLPEYGIPAKIGGDDGGSRGSFKERKKRKGLLV

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=337, Percent_Identity=30.8605341246291, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 41911; Mature: 41911

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDIFINQALQQNDACFIDLRSEGEFAEGSIPGAINIPLFTNEERAKVGIVYKQVGTEA
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCEECCCCCCCEEHHHHHHHHHH
AKRLGLEIASPKLPALYDDISKLAKDKTVFLYCWRGGMRSKYAASILNTLGINLYRIQGG
HHHHCCEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCC
YKAYRKHIHAYLDQDLIPHKCIVLHGLTGVGKTIVLNNLNRFGIPVLDLESIACHRGSAY
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEECCHHHCCCEEEHHHHHHHCCCCC
GKIGLPESPSQKDFESSIVQTLIRAEDKGMVAVECESRRVGKLIVPTSVFNAMSQGYRVL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECHHHHHHHHHCCCEEE
MYASIEKRVQRIIDEYTKGPDNNIEMLKLSTALLKKSLGNKTVEELNQKIDERKFEEVIP
EEHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YLLTKYYDPLYKYPDSPNDEYDLSVDCDDLNEATGIIANWVTSLPEYGIPAKIGGDDGGS
HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
RGSFKERKKRKGLLV
CCCHHHHHHHCCCCC
>Mature Secondary Structure
MLKDIFINQALQQNDACFIDLRSEGEFAEGSIPGAINIPLFTNEERAKVGIVYKQVGTEA
CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCEECCCCCCCEEHHHHHHHHHH
AKRLGLEIASPKLPALYDDISKLAKDKTVFLYCWRGGMRSKYAASILNTLGINLYRIQGG
HHHHCCEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCEEEEECCC
YKAYRKHIHAYLDQDLIPHKCIVLHGLTGVGKTIVLNNLNRFGIPVLDLESIACHRGSAY
HHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEECCHHHCCCEEEHHHHHHHCCCCC
GKIGLPESPSQKDFESSIVQTLIRAEDKGMVAVECESRRVGKLIVPTSVFNAMSQGYRVL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECHHHHHHHHHCCCEEE
MYASIEKRVQRIIDEYTKGPDNNIEMLKLSTALLKKSLGNKTVEELNQKIDERKFEEVIP
EEHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YLLTKYYDPLYKYPDSPNDEYDLSVDCDDLNEATGIIANWVTSLPEYGIPAKIGGDDGGS
HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
RGSFKERKKRKGLLV
CCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA