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The map label for this gene is ftsK [H]

Identifier: 134299783

GI number: 134299783

Start: 2123966

End: 2126248

Strand: Reverse

Name: ftsK [H]

Synonym: Dred_1934

Alternate gene names: 134299783

Gene position: 2126248-2123966 (Counterclockwise)

Preceding gene: 134299785

Following gene: 134299782

Centisome position: 58.93

GC content: 41.22

Gene sequence:

>2283_bases
TTGGATTTATTAAAGAAATTAAAGAATGATTTAAAATATGAAATCTTTGGCATAGGTTTAATATCAATTGCTGTGCTAGG
ACTGATTAGTTTTGCCAATACACCCTTGGGGGCAATCGGGGGTTTTGTGGGACGCGTATTAAAGGGTCTCTTTGGTACCT
GTGGAGGGGTCGCTTTGATGTTTCTCTTTGGCTTTTTTGGTATAAAGCTTATCATAGACCGAAGGCGTACCCCAGTGAAT
ATTAAAGCCTATGGAGCAATACTATTATTTTTTCTCATCCTAACATCTTTAAGTCTTTTTAGTCCCATAAAAGGTACCTT
TATAGAAATTTTAATGGGAATTACCGATGCGGCTACAGCTGGTACTGGTGGTGGGCTTATTGGCTCAATGCTGGCCTTTT
TGTTAATACAATCCTTCGGAAAAGCAGGTACTTATATTCTATTAACTTCGGGATTTATCGTATCCCTTTTACTGATGACC
AATATTTCTATGGCAGTGCTTGCTCAGAAAACAACCTTTAAGGCCAAGGAATGTGTTGAACACACCGGGAAAAGGTTAAA
TGATTTTTTGTTTACAGAAGTTGAGGAAAGTATGGAGTCAGAAAAACCTAAGGAAAGAACAATTACGCCAGTCATTATTA
ATGGTTCTCAGGATGAGATTGACTTTCCGGTTGTTGATCAAAATAAAGAGGATATGAATAATAAAGAAAAAACAGGTCCC
CTTAATTTTGTTATTAATAAAAGACCCAAAACTACTGTTTTAGAACAAGCGTCTCCCTTAGAACCAGAAAGGGATGAAGC
CGATATCACCTATAGTCAGTTATCTTTGAATGATATGAGCTCATTTAATCTACCACCATTAAGCATACTGTCTCGTCCTA
TGAAGGCAAGTAAAAATATCTCCAGTGCAAAGGATATCACTGATAATATTGCTAAACTGGAAGAGACCTTAGAAAGCTTT
GGGATCAAGGCTAAGGTTACACAGGTGTCCCGTGGTCCAGCCATCACTCGTTATGAAATACAGCCTCCTGCTGGTGTAAA
AGTAAGTCGAATTGTTGGCTTGGCCGATGACATTGCTTTATCTATGGCTGCACCGGATGTCCGTATAGAAGCACCCATAC
CTGGTAAAGCAGCGGTGGGAATTGAGGTTCCCAATAAAGAAATTTCCATGGTTCATATTAGAGACTTACTGGAAGCAAAA
GAATTTAGTAATGCAAGTTCCAGCTTAACGGTGGCTCTGGGCAAGGATATAGCAGGGACGCCGATAATGGCTGATTTGAC
AAAAATGCCGCACCTGCTAATTGCCGGTGCGACCGGGGCGGGAAAAAGTGTTTGTATTAACACGCTGATTTCCAGCATTC
TCTTTAAAGCCACACCAGATGAAGTCAAATTTCTCATGATAGATCCGAAGATGGTTGAACTAGCCACCTATAACGGTATA
CCTCATCTGGTTTCTCCGGTTGTAACCAATCCTAAGAAGGCTGCCACCACACTACGATGGGCCGTCCGGGAGATGGAAAA
GCGATATGAGTTGTTTGCCAAGGCTGGGGTTCGTAATATCACCATGTATAACAACCTGTTTAGTGAAAACGAACCCGGTA
CTGGTCAGAATCGCTTACCTTTAATGGTAGTAATTATTGATGAGTTGGCTGACTTAATGATGGTTGCTCCGGCTGATGTA
GAAGATGCCATATGTCGTTTAGCACAAATGGCTCGGGCTGCTGGCATTCATCTAGTTGTAGCCACACAACGTCCGTCAGT
GGATGTCATTACCGGTTTGATAAAAGCAAACATTCCTTCCAGAATTTCCTTTGCAGTGTCATCCCAGGTGGATTCAAGAA
CCATTCTTGATATGGCAGGGGCAGAGAAGCTATTGGGTAAGGGTGATATGTTGTACTTTCCGGTGGGTGCTTCAAAACCA
ATAAGGGTACAGGGAGCCTTTTTGTCTGATAGGGAAGTGGAGGATGTCGTCTCTTTTTTGAAAAAGCAATCTGAACCTAT
CTATGATGATACGGTGGTTAAAGAAGACCCAAAGGCAAAACAAGAGGCAGAGGTTGAAGATGATCTTTTACCTGAGGCTG
TTCGCATTTTAATAGAAACTGGTCATGCATCAATCTCCATGTTACAGCGTCGACTCCATATTGGGTATGCGAGGGCAGCG
AGGTTAATTGACATAATGGAGAAAAAAGGCATTGTAGGGGGTTATGAGGGTAGTAAACCAAGGACCATTTTAATGACCAT
GGAACAATACATACAAACTTTTAAAGAAAATAAACAAGAGTAA

Upstream 100 bases:

>100_bases
TGTTTTGGTATCCTTTTCTTTATTCGGGAAATTCTCTTATTGCAAGGATAAAAGGGTTTTGGAAATTTCTGTAGTATATA
TTACTTGGAGGTGCCACGCC

Downstream 100 bases:

>100_bases
CTTTATATAATGGTCAACTTGCATAAGTTGACCATTATTGATGTGCATGCTATACTGACTTTGATTAACATTACCTAAAT
ATGCCTAAATGTAGAGTGGC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MDLLKKLKNDLKYEIFGIGLISIAVLGLISFANTPLGAIGGFVGRVLKGLFGTCGGVALMFLFGFFGIKLIIDRRRTPVN
IKAYGAILLFFLILTSLSLFSPIKGTFIEILMGITDAATAGTGGGLIGSMLAFLLIQSFGKAGTYILLTSGFIVSLLLMT
NISMAVLAQKTTFKAKECVEHTGKRLNDFLFTEVEESMESEKPKERTITPVIINGSQDEIDFPVVDQNKEDMNNKEKTGP
LNFVINKRPKTTVLEQASPLEPERDEADITYSQLSLNDMSSFNLPPLSILSRPMKASKNISSAKDITDNIAKLEETLESF
GIKAKVTQVSRGPAITRYEIQPPAGVKVSRIVGLADDIALSMAAPDVRIEAPIPGKAAVGIEVPNKEISMVHIRDLLEAK
EFSNASSSLTVALGKDIAGTPIMADLTKMPHLLIAGATGAGKSVCINTLISSILFKATPDEVKFLMIDPKMVELATYNGI
PHLVSPVVTNPKKAATTLRWAVREMEKRYELFAKAGVRNITMYNNLFSENEPGTGQNRLPLMVVIIDELADLMMVAPADV
EDAICRLAQMARAAGIHLVVATQRPSVDVITGLIKANIPSRISFAVSSQVDSRTILDMAGAEKLLGKGDMLYFPVGASKP
IRVQGAFLSDREVEDVVSFLKKQSEPIYDDTVVKEDPKAKQEAEVEDDLLPEAVRILIETGHASISMLQRRLHIGYARAA
RLIDIMEKKGIVGGYEGSKPRTILMTMEQYIQTFKENKQE

Sequences:

>Translated_760_residues
MDLLKKLKNDLKYEIFGIGLISIAVLGLISFANTPLGAIGGFVGRVLKGLFGTCGGVALMFLFGFFGIKLIIDRRRTPVN
IKAYGAILLFFLILTSLSLFSPIKGTFIEILMGITDAATAGTGGGLIGSMLAFLLIQSFGKAGTYILLTSGFIVSLLLMT
NISMAVLAQKTTFKAKECVEHTGKRLNDFLFTEVEESMESEKPKERTITPVIINGSQDEIDFPVVDQNKEDMNNKEKTGP
LNFVINKRPKTTVLEQASPLEPERDEADITYSQLSLNDMSSFNLPPLSILSRPMKASKNISSAKDITDNIAKLEETLESF
GIKAKVTQVSRGPAITRYEIQPPAGVKVSRIVGLADDIALSMAAPDVRIEAPIPGKAAVGIEVPNKEISMVHIRDLLEAK
EFSNASSSLTVALGKDIAGTPIMADLTKMPHLLIAGATGAGKSVCINTLISSILFKATPDEVKFLMIDPKMVELATYNGI
PHLVSPVVTNPKKAATTLRWAVREMEKRYELFAKAGVRNITMYNNLFSENEPGTGQNRLPLMVVIIDELADLMMVAPADV
EDAICRLAQMARAAGIHLVVATQRPSVDVITGLIKANIPSRISFAVSSQVDSRTILDMAGAEKLLGKGDMLYFPVGASKP
IRVQGAFLSDREVEDVVSFLKKQSEPIYDDTVVKEDPKAKQEAEVEDDLLPEAVRILIETGHASISMLQRRLHIGYARAA
RLIDIMEKKGIVGGYEGSKPRTILMTMEQYIQTFKENKQE
>Mature_760_residues
MDLLKKLKNDLKYEIFGIGLISIAVLGLISFANTPLGAIGGFVGRVLKGLFGTCGGVALMFLFGFFGIKLIIDRRRTPVN
IKAYGAILLFFLILTSLSLFSPIKGTFIEILMGITDAATAGTGGGLIGSMLAFLLIQSFGKAGTYILLTSGFIVSLLLMT
NISMAVLAQKTTFKAKECVEHTGKRLNDFLFTEVEESMESEKPKERTITPVIINGSQDEIDFPVVDQNKEDMNNKEKTGP
LNFVINKRPKTTVLEQASPLEPERDEADITYSQLSLNDMSSFNLPPLSILSRPMKASKNISSAKDITDNIAKLEETLESF
GIKAKVTQVSRGPAITRYEIQPPAGVKVSRIVGLADDIALSMAAPDVRIEAPIPGKAAVGIEVPNKEISMVHIRDLLEAK
EFSNASSSLTVALGKDIAGTPIMADLTKMPHLLIAGATGAGKSVCINTLISSILFKATPDEVKFLMIDPKMVELATYNGI
PHLVSPVVTNPKKAATTLRWAVREMEKRYELFAKAGVRNITMYNNLFSENEPGTGQNRLPLMVVIIDELADLMMVAPADV
EDAICRLAQMARAAGIHLVVATQRPSVDVITGLIKANIPSRISFAVSSQVDSRTILDMAGAEKLLGKGDMLYFPVGASKP
IRVQGAFLSDREVEDVVSFLKKQSEPIYDDTVVKEDPKAKQEAEVEDDLLPEAVRILIETGHASISMLQRRLHIGYARAA
RLIDIMEKKGIVGGYEGSKPRTILMTMEQYIQTFKENKQE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=483, Percent_Identity=48.8612836438923, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 82785; Mature: 82785

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLKKLKNDLKYEIFGIGLISIAVLGLISFANTPLGAIGGFVGRVLKGLFGTCGGVALM
CHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLFGFFGIKLIIDRRRTPVNIKAYGAILLFFLILTSLSLFSPIKGTFIEILMGITDAATA
HHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GTGGGLIGSMLAFLLIQSFGKAGTYILLTSGFIVSLLLMTNISMAVLAQKTTFKAKECVE
CCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HTGKRLNDFLFTEVEESMESEKPKERTITPVIINGSQDEIDFPVVDQNKEDMNNKEKTGP
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCC
LNFVINKRPKTTVLEQASPLEPERDEADITYSQLSLNDMSSFNLPPLSILSRPMKASKNI
EEEEECCCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCHHHHCCC
SSAKDITDNIAKLEETLESFGIKAKVTQVSRGPAITRYEIQPPAGVKVSRIVGLADDIAL
CHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
SMAAPDVRIEAPIPGKAAVGIEVPNKEISMVHIRDLLEAKEFSNASSSLTVALGKDIAGT
EECCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
PIMADLTKMPHLLIAGATGAGKSVCINTLISSILFKATPDEVKFLMIDPKMVELATYNGI
CHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCC
PHLVSPVVTNPKKAATTLRWAVREMEKRYELFAKAGVRNITMYNNLFSENEPGTGQNRLP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCCCC
LMVVIIDELADLMMVAPADVEDAICRLAQMARAAGIHLVVATQRPSVDVITGLIKANIPS
EEEEEHHHHHHHHEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCC
RISFAVSSQVDSRTILDMAGAEKLLGKGDMLYFPVGASKPIRVQGAFLSDREVEDVVSFL
CEEEHHHCCCCCHHHHHHHCHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHH
KKQSEPIYDDTVVKEDPKAKQEAEVEDDLLPEAVRILIETGHASISMLQRRLHIGYARAA
HHCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLIDIMEKKGIVGGYEGSKPRTILMTMEQYIQTFKENKQE
HHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLLKKLKNDLKYEIFGIGLISIAVLGLISFANTPLGAIGGFVGRVLKGLFGTCGGVALM
CHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLFGFFGIKLIIDRRRTPVNIKAYGAILLFFLILTSLSLFSPIKGTFIEILMGITDAATA
HHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
GTGGGLIGSMLAFLLIQSFGKAGTYILLTSGFIVSLLLMTNISMAVLAQKTTFKAKECVE
CCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HTGKRLNDFLFTEVEESMESEKPKERTITPVIINGSQDEIDFPVVDQNKEDMNNKEKTGP
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCC
LNFVINKRPKTTVLEQASPLEPERDEADITYSQLSLNDMSSFNLPPLSILSRPMKASKNI
EEEEECCCCCCHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCHHHHCCC
SSAKDITDNIAKLEETLESFGIKAKVTQVSRGPAITRYEIQPPAGVKVSRIVGLADDIAL
CHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
SMAAPDVRIEAPIPGKAAVGIEVPNKEISMVHIRDLLEAKEFSNASSSLTVALGKDIAGT
EECCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
PIMADLTKMPHLLIAGATGAGKSVCINTLISSILFKATPDEVKFLMIDPKMVELATYNGI
CHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECCCC
PHLVSPVVTNPKKAATTLRWAVREMEKRYELFAKAGVRNITMYNNLFSENEPGTGQNRLP
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCCCC
LMVVIIDELADLMMVAPADVEDAICRLAQMARAAGIHLVVATQRPSVDVITGLIKANIPS
EEEEEHHHHHHHHEECCCCHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCC
RISFAVSSQVDSRTILDMAGAEKLLGKGDMLYFPVGASKPIRVQGAFLSDREVEDVVSFL
CEEEHHHCCCCCHHHHHHHCHHHHHCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHH
KKQSEPIYDDTVVKEDPKAKQEAEVEDDLLPEAVRILIETGHASISMLQRRLHIGYARAA
HHCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLIDIMEKKGIVGGYEGSKPRTILMTMEQYIQTFKENKQE
HHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]