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The map label for this gene is yfnH [H]

Identifier: 134299747

GI number: 134299747

Start: 2085636

End: 2086433

Strand: Reverse

Name: yfnH [H]

Synonym: Dred_1897

Alternate gene names: 134299747

Gene position: 2086433-2085636 (Counterclockwise)

Preceding gene: 134299748

Following gene: 134299746

Centisome position: 57.83

GC content: 38.97

Gene sequence:

>798_bases
ATGAAAGTAGTGATTTTATGTGGGGGAAAAGGGACCCGGCTTAAAGAAGAAACGGCTTTCAGACCGAAGCCACTGGTAAC
CGTGGGGAAAAAACCAATACTTTGGCATATCATGAAATATTATTCCCATTACGGTTTCAAAGATTTTATTTTGTGTCTGG
GGTATTTAGGTGAAATGATTAAACAATACTTTATTCAATACGATTTAATGAATAATGACCTAACAATCAGTTTTGACTCA
CGTTCGGAAATACAAATACATAGGAAACAGGATTTGGACTGGCAGGTAACCCTGGCCGATACAGGAATTGAGGCCATGAC
TGGTTGTAGGTTAAAAAGAATAGAAAAATATATTGGTGATGCAGCGGATTTTATGGTCACCTACGGTGACGGTCTTTGTA
ATGTTGATTTAGCTGAACTATATCATTTTCACAGGTCCCATGGTTGCTTAGCCACGGTAACAGGAGTTCGGCCTTTATCT
CGGTTTGGTGAATTGGCTGTGCAAGGGGATACTGTTAAAACCTTTAGTGAAAAAACACAGGTTACCCGTGGTTGGATAAA
TGGTGGTTTTTTTGTCTTTCGTCGAGAAATCTTTAACTATCTAACTAATCAGGATGATTGTGTTTTAGAGCGGGAACCCT
TGGAACATTTAACCATGGATAGTCAATTAAAAGTATTTAAACACAGAGGTTTTTGGCATTGTATGGACACATACCGAGAT
ATGGAGCAGCTAAATAAACTTTGGCAGGTAGGGCATGCTCCCTGGGAGGTTTGGAAAAATGAATCTTTGGCAAAATAA

Upstream 100 bases:

>100_bases
GCATTTCACCGTCGTATGGGTGGTCATTCCAGTGTTCGAATAAGAACGGTGTGGGAGTTTATCAAGAATATGGCTTTCTA
CCGTAAAAGAGGTGTCTTTT

Downstream 100 bases:

>100_bases
AAATGTGCTGATAACCGGATGCTCAGGAATAATTGGCAGTTGGTTGACTCGCAGGCTAGTTGATGAAGGGGCTAATGTGG
TAGGGATTGTTCGGGATCGT

Product: glucose-1-phosphate cytidylyltransferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKVVILCGGKGTRLKEETAFRPKPLVTVGKKPILWHIMKYYSHYGFKDFILCLGYLGEMIKQYFIQYDLMNNDLTISFDS
RSEIQIHRKQDLDWQVTLADTGIEAMTGCRLKRIEKYIGDAADFMVTYGDGLCNVDLAELYHFHRSHGCLATVTGVRPLS
RFGELAVQGDTVKTFSEKTQVTRGWINGGFFVFRREIFNYLTNQDDCVLEREPLEHLTMDSQLKVFKHRGFWHCMDTYRD
MEQLNKLWQVGHAPWEVWKNESLAK

Sequences:

>Translated_265_residues
MKVVILCGGKGTRLKEETAFRPKPLVTVGKKPILWHIMKYYSHYGFKDFILCLGYLGEMIKQYFIQYDLMNNDLTISFDS
RSEIQIHRKQDLDWQVTLADTGIEAMTGCRLKRIEKYIGDAADFMVTYGDGLCNVDLAELYHFHRSHGCLATVTGVRPLS
RFGELAVQGDTVKTFSEKTQVTRGWINGGFFVFRREIFNYLTNQDDCVLEREPLEHLTMDSQLKVFKHRGFWHCMDTYRD
MEQLNKLWQVGHAPWEVWKNESLAK
>Mature_265_residues
MKVVILCGGKGTRLKEETAFRPKPLVTVGKKPILWHIMKYYSHYGFKDFILCLGYLGEMIKQYFIQYDLMNNDLTISFDS
RSEIQIHRKQDLDWQVTLADTGIEAMTGCRLKRIEKYIGDAADFMVTYGDGLCNVDLAELYHFHRSHGCLATVTGVRPLS
RFGELAVQGDTVKTFSEKTQVTRGWINGGFFVFRREIFNYLTNQDDCVLEREPLEHLTMDSQLKVFKHRGFWHCMDTYRD
MEQLNKLWQVGHAPWEVWKNESLAK

Specific function: Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate [H]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=246, Percent_Identity=26.0162601626016, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI11761619, Length=246, Percent_Identity=26.0162601626016, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI133931050, Length=246, Percent_Identity=27.2357723577236, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320148, Length=246, Percent_Identity=27.2357723577236, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355443, Length=244, Percent_Identity=26.6393442622951, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24644084, Length=244, Percent_Identity=26.6393442622951, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 30927; Mature: 30927

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVILCGGKGTRLKEETAFRPKPLVTVGKKPILWHIMKYYSHYGFKDFILCLGYLGEMI
CEEEEEECCCCCCCCHHCCCCCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KQYFIQYDLMNNDLTISFDSRSEIQIHRKQDLDWQVTLADTGIEAMTGCRLKRIEKYIGD
HHHHHHHEEECCCEEEEECCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
AADFMVTYGDGLCNVDLAELYHFHRSHGCLATVTGVRPLSRFGELAVQGDTVKTFSEKTQ
HHHEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHCCEEECCCHHHHHHHHHH
VTRGWINGGFFVFRREIFNYLTNQDDCVLEREPLEHLTMDSQLKVFKHRGFWHCMDTYRD
HHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHHHHHCCHHHHHHHHHH
MEQLNKLWQVGHAPWEVWKNESLAK
HHHHHHHHHCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MKVVILCGGKGTRLKEETAFRPKPLVTVGKKPILWHIMKYYSHYGFKDFILCLGYLGEMI
CEEEEEECCCCCCCCHHCCCCCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KQYFIQYDLMNNDLTISFDSRSEIQIHRKQDLDWQVTLADTGIEAMTGCRLKRIEKYIGD
HHHHHHHEEECCCEEEEECCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
AADFMVTYGDGLCNVDLAELYHFHRSHGCLATVTGVRPLSRFGELAVQGDTVKTFSEKTQ
HHHEEEEECCCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHHCCEEECCCHHHHHHHHHH
VTRGWINGGFFVFRREIFNYLTNQDDCVLEREPLEHLTMDSQLKVFKHRGFWHCMDTYRD
HHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCHHHHHHHHCCHHHHHHHHHH
MEQLNKLWQVGHAPWEVWKNESLAK
HHHHHHHHHCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]