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The map label for this gene is hfq

Identifier: 134299732

GI number: 134299732

Start: 2065750

End: 2065992

Strand: Reverse

Name: hfq

Synonym: Dred_1881

Alternate gene names: 134299732

Gene position: 2065992-2065750 (Counterclockwise)

Preceding gene: 134299733

Following gene: 134299731

Centisome position: 57.26

GC content: 34.16

Gene sequence:

>243_bases
ATGACTAAACCCCAGATAAATTTACAAGATGCCTTTCTGAATCAAGTTAGAAAGGAAAATATCCCTGTTACCATTTTCCT
TATTAATGGTTTTCAATTAAAAGGAATGGTTAAGGGTTTTGATAATTTTACTGTTATTTTGGAAAGTGACGGGAAGCAAC
TGATGGTATACAAACATGCCATTTCTACCATTAGCCCGCTTCGTCCTGTTAATACCTCCTTTTCGGAAAATAAACCGATA
TAA

Upstream 100 bases:

>100_bases
TGTTGCGAATGAAATTATGAAGCAAATGGCAGGAGATTTTTTAACTTTGTAGAAACATTTAAATAAAAATAGAAAATATT
TTCCAATGGAGGGAACCCTC

Downstream 100 bases:

>100_bases
TCAGGCCCAATTGCCCCTCCTGATGGAGGGGCTTCTTGATTTTTGGTCACTATTGCAACCTCCGAGCGTATAATGATAAC
GAGTTATATTTGCCCGGAGG

Product: RNA chaperone Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MTKPQINLQDAFLNQVRKENIPVTIFLINGFQLKGMVKGFDNFTVILESDGKQLMVYKHAISTISPLRPVNTSFSENKPI

Sequences:

>Translated_80_residues
MTKPQINLQDAFLNQVRKENIPVTIFLINGFQLKGMVKGFDNFTVILESDGKQLMVYKHAISTISPLRPVNTSFSENKPI
>Mature_79_residues
TKPQINLQDAFLNQVRKENIPVTIFLINGFQLKGMVKGFDNFTVILESDGKQLMVYKHAISTISPLRPVNTSFSENKPI

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=71, Percent_Identity=52.112676056338, Blast_Score=79, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_DESRM (A4J5Q0)

Other databases:

- EMBL:   CP000612
- RefSeq:   YP_001113228.1
- ProteinModelPortal:   A4J5Q0
- SMR:   A4J5Q0
- STRING:   A4J5Q0
- GeneID:   4958168
- GenomeReviews:   CP000612_GR
- KEGG:   drm:Dred_1881
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   A4J5Q0
- ProtClustDB:   CLSK853598
- BioCyc:   DRED349161:DRED_1881-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9066; Mature: 8935

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPQINLQDAFLNQVRKENIPVTIFLINGFQLKGMVKGFDNFTVILESDGKQLMVYKHA
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCEEEEEEEH
ISTISPLRPVNTSFSENKPI
HHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKPQINLQDAFLNQVRKENIPVTIFLINGFQLKGMVKGFDNFTVILESDGKQLMVYKHA
CCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCEEEEEECCCCEEEEEEEH
ISTISPLRPVNTSFSENKPI
HHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA