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The map label for this gene is spoVK [H]

Identifier: 134299731

GI number: 134299731

Start: 2064686

End: 2065642

Strand: Reverse

Name: spoVK [H]

Synonym: Dred_1880

Alternate gene names: 134299731

Gene position: 2065642-2064686 (Counterclockwise)

Preceding gene: 134299732

Following gene: 134299730

Centisome position: 57.25

GC content: 41.27

Gene sequence:

>957_bases
ATGGTCAAAATTAGTATGTGGAAATATCCGCCTAGGTTTGAACCGCCAAAGCAGGTTGGTATGATAAAAAAACCTTCTTT
ACCAACCAGGCAATCAGTCCAACAGGAGAAATCACAGTTACTGGAAGAAATAGACCGCAAAGCGACCCAAGAGATTTTGG
GAGAATTGGACCAGTTAATCGGCCTTGATAGTGTTAAAAAACTAGTTAGGGAAATTCAAGCCTTTGTGGAGATTCAAAGG
CTTAGACAAAAAGAAAAGTTAATTTTTGAACCCATGGTACTGCATATGATTTTCAAGGGTAATCCTGGTACAGGAAAAAC
CACTGTGGCCAGGATTATTGGTCGACTCTTTAAAGAAATGGCCGTTTTGCCGAAGGGACATCTAATTGAGGTTGAGCGGG
CTGACTTGGTTGGTGAATACATCGGTCATACGGCGGCGAAAACCCGTGATCAAATAAAAAAAGCCATCGGCGGTATTCTT
TTTATTGATGAAGCCTACTCATTAGCCAGAGGCGGCGAAAAGGATTTCGGCAAGGAAGCCATTGATTCTATGGTAACAAG
TATGGAAAACAATAAGGATAATTTAATTATTATCCTGGCGGGTTATCAAGATGAAATGGACTACTTTATGGAAACCAATC
CCGGTTTGCGTTCACGTTTCCCAATACATATTACCTTCCCAGACTATTCCATTGATCAACTAATGGATATTGCTGACCTT
ATGTTAAAACAGCGCCAATATGTATTGGCTCCAATGGCCAGGGAGGAATTATATAAGATTGTTGCGCAGCAGACTCGTAA
ACACGAGCATAGTGGCAATGCCAGGTTAGTTCGTAACTTAATAGAGAGGGCCATGCGAATGCAGGCTGTTCGATTAATAG
CAAGAAAAAAAATAACCAGGCAGGACCTAATGGCTATCAATAAAGAAGACTTGACAGAGGCTCTGGAGGGAATATAA

Upstream 100 bases:

>100_bases
CAATTGCCCCTCCTGATGGAGGGGCTTCTTGATTTTTGGTCACTATTGCAACCTCCGAGCGTATAATGATAACGAGTTAT
ATTTGCCCGGAGGTGCTTCC

Downstream 100 bases:

>100_bases
TACCTTCAGGGCCTAAATCTAATTGACAAAACGGAGGAATTATGCATCTAGATATTTTGGACAAGTTAGCCAATGAAGTA
GAAATGGAAGTACAGTCTGT

Product: ATPase central domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MVKISMWKYPPRFEPPKQVGMIKKPSLPTRQSVQQEKSQLLEEIDRKATQEILGELDQLIGLDSVKKLVREIQAFVEIQR
LRQKEKLIFEPMVLHMIFKGNPGTGKTTVARIIGRLFKEMAVLPKGHLIEVERADLVGEYIGHTAAKTRDQIKKAIGGIL
FIDEAYSLARGGEKDFGKEAIDSMVTSMENNKDNLIIILAGYQDEMDYFMETNPGLRSRFPIHITFPDYSIDQLMDIADL
MLKQRQYVLAPMAREELYKIVAQQTRKHEHSGNARLVRNLIERAMRMQAVRLIARKKITRQDLMAINKEDLTEALEGI

Sequences:

>Translated_318_residues
MVKISMWKYPPRFEPPKQVGMIKKPSLPTRQSVQQEKSQLLEEIDRKATQEILGELDQLIGLDSVKKLVREIQAFVEIQR
LRQKEKLIFEPMVLHMIFKGNPGTGKTTVARIIGRLFKEMAVLPKGHLIEVERADLVGEYIGHTAAKTRDQIKKAIGGIL
FIDEAYSLARGGEKDFGKEAIDSMVTSMENNKDNLIIILAGYQDEMDYFMETNPGLRSRFPIHITFPDYSIDQLMDIADL
MLKQRQYVLAPMAREELYKIVAQQTRKHEHSGNARLVRNLIERAMRMQAVRLIARKKITRQDLMAINKEDLTEALEGI
>Mature_318_residues
MVKISMWKYPPRFEPPKQVGMIKKPSLPTRQSVQQEKSQLLEEIDRKATQEILGELDQLIGLDSVKKLVREIQAFVEIQR
LRQKEKLIFEPMVLHMIFKGNPGTGKTTVARIIGRLFKEMAVLPKGHLIEVERADLVGEYIGHTAAKTRDQIKKAIGGIL
FIDEAYSLARGGEKDFGKEAIDSMVTSMENNKDNLIIILAGYQDEMDYFMETNPGLRSRFPIHITFPDYSIDQLMDIADL
MLKQRQYVLAPMAREELYKIVAQQTRKHEHSGNARLVRNLIERAMRMQAVRLIARKKITRQDLMAINKEDLTEALEGI

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641
- InterPro:   IPR014232 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 36531; Mature: 36531

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKISMWKYPPRFEPPKQVGMIKKPSLPTRQSVQQEKSQLLEEIDRKATQEILGELDQLI
CEEEECCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDSVKKLVREIQAFVEIQRLRQKEKLIFEPMVLHMIFKGNPGTGKTTVARIIGRLFKEM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AVLPKGHLIEVERADLVGEYIGHTAAKTRDQIKKAIGGILFIDEAYSLARGGEKDFGKEA
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCHHHHHH
IDSMVTSMENNKDNLIIILAGYQDEMDYFMETNPGLRSRFPIHITFPDYSIDQLMDIADL
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
MLKQRQYVLAPMAREELYKIVAQQTRKHEHSGNARLVRNLIERAMRMQAVRLIARKKITR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDLMAINKEDLTEALEGI
HHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MVKISMWKYPPRFEPPKQVGMIKKPSLPTRQSVQQEKSQLLEEIDRKATQEILGELDQLI
CEEEECCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDSVKKLVREIQAFVEIQRLRQKEKLIFEPMVLHMIFKGNPGTGKTTVARIIGRLFKEM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AVLPKGHLIEVERADLVGEYIGHTAAKTRDQIKKAIGGILFIDEAYSLARGGEKDFGKEA
HHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCHHHHHH
IDSMVTSMENNKDNLIIILAGYQDEMDYFMETNPGLRSRFPIHITFPDYSIDQLMDIADL
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
MLKQRQYVLAPMAREELYKIVAQQTRKHEHSGNARLVRNLIERAMRMQAVRLIARKKITR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDLMAINKEDLTEALEGI
HHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1787791; 9384377 [H]