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The map label for this gene is sdhB [H]

Identifier: 134299721

GI number: 134299721

Start: 2053905

End: 2054651

Strand: Reverse

Name: sdhB [H]

Synonym: Dred_1868

Alternate gene names: 134299721

Gene position: 2054651-2053905 (Counterclockwise)

Preceding gene: 134299722

Following gene: 134299720

Centisome position: 56.95

GC content: 42.7

Gene sequence:

>747_bases
ATGAGTAAAATGGTGTCCTTAAAGATTAAACGTCAGTCTGATGTATCCACAGCGGCTTATTGGGAAGAATTTATGATTCC
ATATAAAGAAAAAATGAATGTTATATCTCTTTTAAAGGAGATTCAAAAGAACCCAGTGAATGCCAAGGGAGAAGCAACAA
CACCCGTGGTTTGGGAGTGCAACTGTTTAGAAGAAGTATGCGGCGCTTGTACCATGCTTATTAATGGAAAAGCACGGCAG
GCATGTTCGGCTCTGGTTGACCAGCTTCAGCAACCCATTGTATTAGAACCCTTAAGTAAATTCCCCCTTGTGCGTGATTT
AATGGTTGATCGTTCTATTATGTTTGATCATTTAAAGAAGGTTAAGGCATGGATTCCCATTGATGGAACATACGACCTTG
GTCCGGGACTCCGTATGGCTCAAAGGGTTCAGGAAGACTCCTACCCCATTTCCCGCTGCATGACCTGTGGCTGTTGTTTG
GAAGCTTGCCCCAATGTTAATAGCAAATCAAAATTTATTGGACCAGCTCCGTTGGCCCAAGTTAAACTGTTTAACTCTCA
CCCCACTGGTGCCATGAACCAAGAAGAAAGACTGGATGCCATCATGGGAGTGGGTGGTATCACAGACTGTGGGAATGCAC
AGAATTGTGTAAAGGTATGTCCTAAACAAATCCCGCTGGCTAAAACCATTGCGCAACTAAATAGAGATACAACAATACAT
GGTATAAAAAGATGGTTAGGCAGGTAA

Upstream 100 bases:

>100_bases
ATACTTTCAATGGTCCAGAATTAACCTATGAAGATATAGATACTTCGCTTATTAAGCCAAGGCCGCGGAGATATGATGTT
GATAAAGGGGCGTTGAATAA

Downstream 100 bases:

>100_bases
ATAATAGAATAAAAGGATTTTAAGTTCACTATCCTATGTGAAATTATTCAATACAGGAGGAGTAGCAAGATGAAAAGGAA
GAAAATTACTATTGTGGGTG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSKMVSLKIKRQSDVSTAAYWEEFMIPYKEKMNVISLLKEIQKNPVNAKGEATTPVVWECNCLEEVCGACTMLINGKARQ
ACSALVDQLQQPIVLEPLSKFPLVRDLMVDRSIMFDHLKKVKAWIPIDGTYDLGPGLRMAQRVQEDSYPISRCMTCGCCL
EACPNVNSKSKFIGPAPLAQVKLFNSHPTGAMNQEERLDAIMGVGGITDCGNAQNCVKVCPKQIPLAKTIAQLNRDTTIH
GIKRWLGR

Sequences:

>Translated_248_residues
MSKMVSLKIKRQSDVSTAAYWEEFMIPYKEKMNVISLLKEIQKNPVNAKGEATTPVVWECNCLEEVCGACTMLINGKARQ
ACSALVDQLQQPIVLEPLSKFPLVRDLMVDRSIMFDHLKKVKAWIPIDGTYDLGPGLRMAQRVQEDSYPISRCMTCGCCL
EACPNVNSKSKFIGPAPLAQVKLFNSHPTGAMNQEERLDAIMGVGGITDCGNAQNCVKVCPKQIPLAKTIAQLNRDTTIH
GIKRWLGR
>Mature_247_residues
SKMVSLKIKRQSDVSTAAYWEEFMIPYKEKMNVISLLKEIQKNPVNAKGEATTPVVWECNCLEEVCGACTMLINGKARQA
CSALVDQLQQPIVLEPLSKFPLVRDLMVDRSIMFDHLKKVKAWIPIDGTYDLGPGLRMAQRVQEDSYPISRCMTCGCCLE
ACPNVNSKSKFIGPAPLAQVKLFNSHPTGAMNQEERLDAIMGVGGITDCGNAQNCVKVCPKQIPLAKTIAQLNRDTTIHG
IKRWLGR

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=194, Percent_Identity=25.7731958762887, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1790596, Length=236, Percent_Identity=26.271186440678, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786943, Length=233, Percent_Identity=28.3261802575107, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533915, Length=194, Percent_Identity=27.8350515463918, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322987, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643156, Length=199, Percent_Identity=29.6482412060301, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17137106, Length=199, Percent_Identity=26.1306532663317, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27529; Mature: 27397

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
9.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKMVSLKIKRQSDVSTAAYWEEFMIPYKEKMNVISLLKEIQKNPVNAKGEATTPVVWEC
CCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEC
NCLEEVCGACTMLINGKARQACSALVDQLQQPIVLEPLSKFPLVRDLMVDRSIMFDHLKK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCHHHCHHHHHHHHHHHHHHHHHHH
VKAWIPIDGTYDLGPGLRMAQRVQEDSYPISRCMTCGCCLEACPNVNSKSKFIGPAPLAQ
HHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VKLFNSHPTGAMNQEERLDAIMGVGGITDCGNAQNCVKVCPKQIPLAKTIAQLNRDTTIH
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHCCCHHHHHHHHCCCCHHH
GIKRWLGR
HHHHHHCC
>Mature Secondary Structure 
SKMVSLKIKRQSDVSTAAYWEEFMIPYKEKMNVISLLKEIQKNPVNAKGEATTPVVWEC
CCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEC
NCLEEVCGACTMLINGKARQACSALVDQLQQPIVLEPLSKFPLVRDLMVDRSIMFDHLKK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCHHHCHHHHHHHHHHHHHHHHHHH
VKAWIPIDGTYDLGPGLRMAQRVQEDSYPISRCMTCGCCLEACPNVNSKSKFIGPAPLAQ
HHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VKLFNSHPTGAMNQEERLDAIMGVGGITDCGNAQNCVKVCPKQIPLAKTIAQLNRDTTIH
EEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHCCCHHHHHHHHCCCCHHH
GIKRWLGR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]